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5M5S
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BU of 5m5s by Molmil
Clathrin heavy chain N-terminal domain bound to amphiphysin clathrin-box motif
Descriptor: Amphiphysin, Clathrin heavy chain 1, GLYCEROL
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-22
Release date:2016-11-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5V
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BU of 5m5v by Molmil
Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large antigen (clade 2)
Descriptor: Clathrin heavy chain 1, GLYCEROL, Large delta antigen
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-22
Release date:2016-11-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5U
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BU of 5m5u by Molmil
Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large antigen (clade 1)
Descriptor: Clathrin heavy chain 1, GLYCEROL, Large delta antigen
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-22
Release date:2016-11-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
6I2M
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BU of 6i2m by Molmil
Crystal structure of vaccinia virus protein A55 BTB-Back domain in complex with human Cullin-3 N-terminus
Descriptor: Cullin-3, Kelch repeat and BTB domain-containing protein A55
Authors:Gao, G, Graham, S.C.
Deposit date:2018-11-01
Release date:2019-01-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of cullin-3 (Cul3) ubiquitin ligase subversion by vaccinia virus protein A55.
J.Biol.Chem., 294, 2019
3ZED
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BU of 3zed by Molmil
X-ray structure of the birnavirus VP1-VP3 complex
Descriptor: CAPSID PROTEIN VP3, GLYCEROL, POTASSIUM ION, ...
Authors:Bahar, M.W, Sarin, L.P, Graham, S.C, Pang, J, Bamford, D.H, Stuart, D.I, Grimes, J.M.
Deposit date:2012-12-04
Release date:2013-01-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a Vp1-Vp3 Complex Suggests How Birnaviruses Package the Vp1 Polymerase.
J.Virol., 87, 2013
3ZR5
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BU of 3zr5 by Molmil
STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Deane, J.E, Graham, S.C, Kim, N.N, Stein, P.E, Mcnair, R, Cachon-Gonzalez, M.B, Cox, T.M, Read, R.J.
Deposit date:2011-06-14
Release date:2011-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
3ZYK
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BU of 3zyk by Molmil
Structure of CALM (PICALM) ANTH domain
Descriptor: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN
Authors:Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
Deposit date:2011-08-23
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3ZYM
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BU of 3zym by Molmil
Structure of CALM (PICALM) in complex with VAMP8
Descriptor: GLYCEROL, PHOSPHATE ION, PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN, ...
Authors:Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
Deposit date:2011-08-23
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3ZR6
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BU of 3zr6 by Molmil
STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE IN COMPLEX WITH GALACTOSE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Deane, J.E, Graham, S.C, Kim, N.N, Stein, P.E, Mcnair, R, Cachon-Gonzalez, M.B, Cox, T.M, Read, R.J.
Deposit date:2011-06-14
Release date:2011-09-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
4BBB
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BU of 4bbb by Molmil
THE STRUCTURE OF VACCINIA VIRUS N1 Q61Y MUTANT
Descriptor: N1L
Authors:Maluquer de Motes, C, Cooray, S, McGourty, K, Ren, H, Bahar, M.W, Stuart, D.I, Grimes, J.M, Graham, S.C, Smith, G.L.
Deposit date:2012-09-21
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
4BBD
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BU of 4bbd by Molmil
THE STRUCTURE OF VACCINIA VIRUS N1 R58Y MUTANT
Descriptor: N1L
Authors:Maluquer de Motes, C, Cooray, S, McGourty, K, Ren, H, Bahar, M.W, Stuart, D.I, Grimes, J.M, Graham, S.C, Smith, G.L.
Deposit date:2012-09-21
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
4BBC
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BU of 4bbc by Molmil
THE STRUCTURE OF VACCINIA VIRUS N1 R71Y MUTANT
Descriptor: N1L
Authors:Maluquer de Motes, C, Cooray, S, McGourty, K, Ren, H, Bahar, M.W, Stuart, D.I, Grimes, J.M, Graham, S.C, Smith, G.L.
Deposit date:2012-09-21
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
3ZYL
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BU of 3zyl by Molmil
Structure of a truncated CALM (PICALM) ANTH domain
Descriptor: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN
Authors:Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
Deposit date:2011-08-23
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
4CCC
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BU of 4ccc by Molmil
STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH 4NBDG: ENZYME-SUBSTRATE COMPLEX
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitrophenyl beta-D-galactopyranoside, ...
Authors:Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E.
Deposit date:2013-10-21
Release date:2013-12-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
4CCE
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BU of 4cce by Molmil
STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME- PRODUCT COMPLEX
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E.
Deposit date:2013-10-21
Release date:2013-12-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
2VT1
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BU of 2vt1 by Molmil
Crystal structure of the cytoplasmic domain of Spa40, the specificity switch for the Shigella flexneri Type III Secretion System
Descriptor: SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAS
Authors:Deane, J.E, Graham, S.C, Mitchell, E.P, Flot, D, Johnson, S, Lea, S.M.
Deposit date:2008-05-08
Release date:2008-05-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Spa40, the Specificity Switch for the Shigella Flexneri Type III Secretion System
Mol.Microbiol., 69, 2008
3P5J
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BU of 3p5j by Molmil
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Bubeck, D, Graham, S.C, Jones, E.Y.
Deposit date:2010-10-08
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
2VSC
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BU of 2vsc by Molmil
Structure of the immunoglobulin-superfamily ectodomain of human CD47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, MAGNESIUM ION
Authors:Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N.
Deposit date:2008-04-22
Release date:2008-08-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
3P87
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BU of 3p87 by Molmil
Structure of human PCNA bound to RNASEH2B PIP box peptide
Descriptor: Proliferating cell nuclear antigen, Ribonuclease H2 subunit B
Authors:Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
Deposit date:2010-10-13
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
2WNG
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BU of 2wng by Molmil
complete extracellular structure of human signal regulatory protein (SIRP) alpha
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1
Authors:Hatherley, D, Graham, S.C, Harlos, K, Stuart, D.I, Barclay, A.N.
Deposit date:2009-07-09
Release date:2009-07-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution.
J.Biol.Chem., 284, 2009
2X46
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BU of 2x46 by Molmil
Crystal Structure of SeMet Arg r 1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALLERGEN ARG R 1
Authors:Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I.
Deposit date:2010-01-28
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick
To be Published
3P83
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BU of 3p83 by Molmil
Structure of the PCNA:RNase HII complex from Archaeoglobus fulgidus.
Descriptor: DNA polymerase sliding clamp, Ribonuclease HII
Authors:Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
Deposit date:2010-10-13
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
2WFO
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BU of 2wfo by Molmil
Crystal structure of Machupo virus envelope glycoprotein GP1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN 1
Authors:Bowden, T.A, Crispin, M, Graham, S.C, Harvey, D.J, Grimes, J.M, Jones, E.Y, Stuart, D.I.
Deposit date:2009-04-09
Release date:2009-06-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Unusual Molecular Architecture of the Machupo Virus Attachment Glycoprotein.
J.Virol., 83, 2009
2X45
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BU of 2x45 by Molmil
Crystal Structure of Arg r 1 in complex with histamine
Descriptor: ALLERGEN ARG R 1, HISTAMINE
Authors:Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I.
Deposit date:2010-01-28
Release date:2011-02-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick
To be Published
3P56
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BU of 3p56 by Molmil
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Bubeck, D, Graham, S.C, Jones, E.Y.
Deposit date:2010-10-08
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.06 Å)
Cite:The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011

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