5CJH
| Crystal Structure of Eukaryotic Oxoiron MagKatG2 at pH 8.5 | Descriptor: | Catalase-peroxidase 2, HYDROXIDE ION, Peroxidized Heme | Authors: | Gasselhuber, B, Obinger, C, Fita, I, Carpena, X. | Deposit date: | 2015-07-14 | Release date: | 2015-09-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Eukaryotic Catalase-Peroxidase: The Role of the Trp-Tyr-Met Adduct in Protein Stability, Substrate Accessibility, and Catalysis of Hydrogen Peroxide Dismutation. Biochemistry, 54, 2015
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5DOU
| Crystal Structure of Human Carbamoyl phosphate synthetase I (CPS1), ligand-bound form | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | de Cima, S, Polo, L.M, Fita, I, Rubio, V. | Deposit date: | 2015-09-11 | Release date: | 2015-12-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis. Sci Rep, 5, 2015
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5DOT
| Crystal Structure of Human Carbamoyl phosphate synthetase I (CPS1), apo form | Descriptor: | 1,2-ETHANEDIOL, Carbamoyl-phosphate synthase [ammonia], mitochondrial, ... | Authors: | Polo, L.M, de Cima, S, Fita, I, Rubio, V. | Deposit date: | 2015-09-11 | Release date: | 2015-12-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis. Sci Rep, 5, 2015
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1A3R
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5C1V
| CRYSTAL STRUCTURE ANALYSIS OF CATALYTIC SUBUNIT OF HUMAN CALCINEURIN | Descriptor: | FE (III) ION, PHOSPHATE ION, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, ... | Authors: | Guasch, A, Fita, I, Perez-Luque, R, Aparicio, D, Aranguren-Ibanez, A, Perez-Riba, M. | Deposit date: | 2015-06-15 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization. Plos One, 10, 2015
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1GG9
| CRYSTAL STRUCTURE OF CATALASE HPII FROM ESCHERICHIA COLI, HIS128ASN VARIANT. | Descriptor: | CATALASE HPII, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Melik-Adamyan, W.R, Bravo, J, Carpena, X, Switala, J, Mate, M.J, Fita, I, Loewen, P.C. | Deposit date: | 2000-08-11 | Release date: | 2000-08-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Substrate flow in catalases deduced from the crystal structures of active site variants of HPII from Escherichia coli. Proteins, 44, 2001
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3F9P
| Crystal structure of myeloperoxidase from human leukocytes | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Carpena, X, Fita, I, Obinger, C. | Deposit date: | 2008-11-14 | Release date: | 2009-07-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Essential role of proximal histidine-asparagine interaction in Mammalian peroxidases. J.Biol.Chem., 284, 2009
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2O4I
| Structure of TREX1 in complex with DNA | Descriptor: | 5'-D(*GP*CP*TP*AP*GP*GP*CP*AP*GP*GP*AP*AP*CP*CP*CP*CP*TP*CP*CP*TP*CP*CP*CP*CP*T)-3', Three prime repair exonuclease 1 | Authors: | Brucet, M, Macias, M.J, Fita, I, Celada, A. | Deposit date: | 2006-12-04 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains. J.Biol.Chem., 282, 2007
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2O4G
| Structure of TREX1 in complex with a nucleotide | Descriptor: | MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, Three prime repair exonuclease 1 | Authors: | Brucet, M, Macias, M.J, Fita, I, Celada, A. | Deposit date: | 2006-12-04 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains. J.Biol.Chem., 282, 2007
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2OBY
| Crystal structure of Human P53 inducible oxidoreductase (TP53I3,PIG3) | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative quinone oxidoreductase | Authors: | Porte, S, Valencia, E, Farres, J, Fita, I, Pike, A.C.W, Shafqat, N, Debreczeni, J, Johansson, C, Haroniti, A, Gileadi, O, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, von Delft, F, Oppermann, U, Pares, X. | Deposit date: | 2006-12-20 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human P53 inducible oxidoreductase (TP53I3, PIG3) To be Published
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2PMP
| Structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from the isoprenoid biosynthetic pathway of Arabidopsis thaliana | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CHLORIDE ION, CYTIDINE-5'-MONOPHOSPHATE, ... | Authors: | Calisto, B.M, Perez-Gil, J, Querol-Audi, J, Fita, I, Imperial, S. | Deposit date: | 2007-04-23 | Release date: | 2007-09-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Biosynthesis of isoprenoids in plants: Structure of the 2C-methyl-D-erithrytol 2,4-cyclodiphosphate synthase from Arabidopsis thaliana. Comparison with the bacterial enzymes. Protein Sci., 16, 2007
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3DPR
| Human rhinovirus 2 bound to a concatamer of the VLDL receptor module V3 | Descriptor: | CALCIUM ION, LAURIC ACID, LDL-receptor class A 3, ... | Authors: | Querol-Audi, J, Pous, J, Fita, I, Verdaguer, N. | Deposit date: | 2008-07-09 | Release date: | 2009-04-07 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition Febs Lett., 583, 2009
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3FRO
| Crystal structure of Pyrococcus abyssi glycogen synthase with open and closed conformations | Descriptor: | 1,5-anhydro-D-fructose, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GlgA glycogen synthase, ... | Authors: | Diaz, A, Guinovart, J.J, Fita, I, Ferrer, J.C. | Deposit date: | 2009-01-08 | Release date: | 2010-01-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Lyase activity of glycogen synthase: Is an elimination/addition mechanism a possible reaction pathway for retaining glycosyltransferases? IUBMB Life, 64, 2012
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3OB6
| Structure of AdiC(N101A) in the open-to-out Arg+ bound conformation | Descriptor: | ARGININE, AdiC arginine:agmatine antiporter | Authors: | Carpena, X, Kowalczyk, L, Ratera, M, Valencia, E, Vazquez-lbar, J.L, Fita, I, Palacin, M. | Deposit date: | 2010-08-06 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular basis of substrate-induced permeation by an amino acid antiporter. Proc.Natl.Acad.Sci.USA, 108, 2011
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3P9P
| Structure of I274V variant of E. coli KatE | Descriptor: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE 17R, 18S, ... | Authors: | Loewen, P.C, Jha, V, Louis, S, Chelikani, P, Carpena, X, Fita, I. | Deposit date: | 2010-10-18 | Release date: | 2010-12-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli. Biochemistry, 50, 2011
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3P9Q
| Structure of I274C variant of E. coli KatE | Descriptor: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE 17R, 18S, ... | Authors: | Loewen, P.C, Jha, V, Louis, S, Chelikani, P, Carpena, X, Fita, I. | Deposit date: | 2010-10-18 | Release date: | 2010-12-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli. Biochemistry, 50, 2011
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3P9S
| Structure of I274A variant of E. coli KatE | Descriptor: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE 17R, 18S, ... | Authors: | Loewen, P.C, Jha, V, Louis, S, Chelikani, P, Carpena, X, Fita, I. | Deposit date: | 2010-10-18 | Release date: | 2010-12-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli. Biochemistry, 50, 2011
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3P9R
| Structure of I274G variant of E. coli KatE | Descriptor: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase HPII | Authors: | Loewen, P.C, Jha, V, Louis, S, Chelikani, P, Carpena, X, Fita, I. | Deposit date: | 2010-10-18 | Release date: | 2010-12-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli. Biochemistry, 50, 2011
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2BUF
| Arginine Feed-Back Inhibitable Acetylglutamate Kinase | Descriptor: | ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Ramon-Maiques, S, Fernandez-Murga, M.L, Vagin, A, Fita, I, Rubio, V. | Deposit date: | 2005-06-12 | Release date: | 2005-12-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural Bases of Feed-Back Control of Arginine Biosynthesis, Revealed by the Structure of Two Hexameric N-Acetylglutamate Kinases, from Thermotoga Maritima and Pseudomonas Aeruginosa J.Mol.Biol., 356, 2006
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5OBU
| Mycoplasma genitalium DnaK deletion mutant lacking SBDalpha in complex with AMPPNP. | Descriptor: | Chaperone protein DnaK, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Adell, M, Calisto, B, Fita, I, Martinelli, L. | Deposit date: | 2017-06-29 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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5OBW
| Mycoplasma genitalium DnaK-NBD in complex with ATP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ... | Authors: | Adell, M, Calisto, B, Fita, I, Martinelli, L. | Deposit date: | 2017-06-29 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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5OBY
| Mycoplasma genitalium DnaK-NBD in complex with AMP-PNP | Descriptor: | Chaperone protein DnaK, GLYCEROL, MAGNESIUM ION, ... | Authors: | Adell, M, Calisto, B, Fita, I, Martinelli, L. | Deposit date: | 2017-06-29 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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5OBV
| Mycoplasma genitalium DnaK deletion mutant lacking SBDalpha in complex with ADP and Pi. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein DnaK, PHOSPHATE ION | Authors: | Adell, M, Calisto, B, Fita, I, Martinelli, L. | Deposit date: | 2017-06-29 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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5OBX
| Mycoplasma genitalium DnaK-NBD | Descriptor: | Chaperone protein DnaK, GLYCEROL, SULFATE ION, ... | Authors: | Adell, M, Calisto, B, Fita, I, Martinelli, L. | Deposit date: | 2017-06-29 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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2DH3
| Crystal Structure of human ED-4F2hc | Descriptor: | 4F2 cell-surface antigen heavy chain, ZINC ION | Authors: | Fort, J, Fita, I, Palacin, M. | Deposit date: | 2006-03-21 | Release date: | 2007-03-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane. J.Biol.Chem., 282, 2007
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