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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic Gain-of-Function K659M Mutation Identified in Cervical Cancer.
Descriptor:	CITRATE ANION, Fibroblast growth factor receptor 2, MAGNESIUM ION, ...
Authors:	Chen, H, Mohammadi, M.
Deposit date:	2013-02-15
Release date:	2013-08-07
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.2972 Å)
Cite:	Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep, 4, 2013

HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
Descriptor:	FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION
Authors:	Lee, C.-H, Kuriyan, J.
Deposit date:	1996-06-29
Release date:	1997-01-11
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell(Cambridge,Mass.), 85, 1996

COCRYSTAL STRUCTURE OF UREA-SUBSTITUTED PHOSPHOPEPTIDE COMPLEX
Descriptor:	4-[3-CARBOXYMETHYL-3-(4-PHOSPHONOOXY-BENZYL)-UREIDO]-4-[(3-CYCLOHEXYL-PROPYL)-METHYL-CARBAMOYL]BUTYRIC ACID, PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN
Authors:	Holland, D.R, Rubin, J.R.
Deposit date:	1997-09-18
Release date:	1998-02-25
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand. J.Med.Chem., 40, 1997

SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE
Descriptor:	PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR, SHC
Authors:	Zhou, M.-M, Meadows, R.P, Logan, T.M, Yoon, H.S, Wade, W.R, Ravichandran, K.S, Burakoff, S.J, Feisk, S.W.
Deposit date:	1996-03-27
Release date:	1997-05-15
Last modified:	2022-03-02
Method:	SOLUTION NMR
Cite:	Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor. Proc.Natl.Acad.Sci.USA, 92, 1995