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6B9H
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BU of 6b9h by Molmil
Complex of Hook Domain with a Dynein Light Intermediate Chain Peptide
Descriptor: Cytoplasmic dynein 1 light intermediate chain 1, Protein Hook homolog 3
Authors:Lee, I.G, Dominguez, R.
Deposit date:2017-10-10
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity.
Nat Commun, 9, 2018
6BCY
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BU of 6bcy by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T360
Descriptor: 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BD1
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BU of 6bd1 by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at S366
Descriptor: 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, Insulin receptor substrate protein of 53 kDa, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6C1D
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BU of 6c1d by Molmil
High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C1G
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BU of 6c1g by Molmil
High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C1H
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BU of 6c1h by Molmil
High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BQT
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BU of 6bqt by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360
Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2017-11-28
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
3E5H
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BU of 3e5h by Molmil
Crystal Structure of Rab28 GTPase in the Active (GppNHp-bound) Form
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Lee, S.H, Baek, K, Li, Y, Dominguez, R.
Deposit date:2008-08-13
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Large nucleotide-dependent conformational change in Rab28.
Febs Lett., 582, 2008
6UHC
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BU of 6uhc by Molmil
CryoEM structure of human Arp2/3 complex with bound NPFs
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:Zimmet, A, van Eeuwen, T, Dominguez, R.
Deposit date:2019-09-27
Release date:2020-07-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.
Sci Adv, 6, 2020
1TN4
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BU of 1tn4 by Molmil
FOUR CALCIUM TNC
Descriptor: CALCIUM ION, TROPONIN C
Authors:Love, M.L, Dominguez, R, Houdusse, A, Cohen, C.
Deposit date:1997-09-18
Release date:1998-04-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily.
Structure, 5, 1997
1S70
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BU of 1s70 by Molmil
Complex between protein ser/thr phosphatase-1 (delta) and the myosin phosphatase targeting subunit 1 (MYPT1)
Descriptor: 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130), MANGANESE (II) ION, Serine/threonine protein phosphatase PP1-beta (or delta) catalytic subunit, ...
Authors:Kerff, F, Terrak, M, Dominguez, R.
Deposit date:2004-01-28
Release date:2004-06-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of protein phosphatase 1 regulation
Nature, 429, 2004
3T62
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BU of 3t62 by Molmil
Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin
Descriptor: Chymotrypsinogen A, Kunitz-type proteinase inhibitor SHPI-1, SULFATE ION
Authors:Garcia-Fernandez, R, Dominguez, R, Oberthuer, D, Pons, T, Gonzalez-Gonzalez, Y, Chavez, M.A, Betzel, C, Redecke, L.
Deposit date:2011-07-28
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into chymotrypsin inhibition by the Kunitz-type inhibitor-1 from the marine invertebrate Stichodactyla helianthus
To be Published
1M45
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BU of 1m45 by Molmil
CRYSTAL STRUCTURE OF MLC1P BOUND TO IQ2 OF MYO2P, A CLASS V MYOSIN
Descriptor: IQ2 Motif from MYO2P, A Class V Myosin, Myosin light chain
Authors:Terrak, M, Dominguez, R.
Deposit date:2002-07-02
Release date:2003-02-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications
Embo J., 22, 2003
1M46
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BU of 1m46 by Molmil
CRYSTAL STRUCTURE OF MLC1P BOUND TO IQ4 OF MYO2P, A CLASS V MYOSIN
Descriptor: IQ4 Motif from MYO2P, A Class V Myosin, Myosin light chain
Authors:Terrak, M, Dominguez, R.
Deposit date:2002-07-02
Release date:2002-11-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications
Embo J., 22, 2003
4JS0
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BU of 4js0 by Molmil
Complex of Cdc42 with the CRIB-PR domain of IRSp53
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Brain-specific angiogenesis inhibitor 1-associated protein 2, Cell division control protein 42 homolog, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2013-03-22
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.
Nat.Struct.Mol.Biol., 21, 2014
4L79
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BU of 4l79 by Molmil
Crystal Structure of nucleotide-free Myosin 1b residues 1-728 with bound Calmodulin
Descriptor: Calmodulin, MAGNESIUM ION, Unconventional myosin-Ib
Authors:Shuman, H, Zwolak, A, Dominguez, R, Ostap, E.M.
Deposit date:2013-06-13
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning.
Proc.Natl.Acad.Sci.USA, 111, 2014
4J7O
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BU of 4j7o by Molmil
Structure of the N-terminal Repeat Domain of Rickettsia Sca2
Descriptor: GLYCEROL, Putative surface cell antigen sca2
Authors:Madasu, Y, Dominguez, R.
Deposit date:2013-02-13
Release date:2013-07-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.175 Å)
Cite:Rickettsia Sca2 has evolved formin-like activity through a different molecular mechanism.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K17
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BU of 4k17 by Molmil
Crystal Structure of mouse CARMIL residues 1-668
Descriptor: CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, Leucine-rich repeat-containing protein 16A, ...
Authors:Zwolak, A, Dominguez, R.
Deposit date:2013-04-04
Release date:2013-10-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.895 Å)
Cite:CARMIL leading edge localization depends on a non-canonical PH domain and dimerization.
Nat Commun, 4, 2013
2D1K
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BU of 2d1k by Molmil
Ternary complex of the WH2 domain of mim with actin-dnase I
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chereau, D, Kerff, F, Dominguez, R.
Deposit date:2005-08-26
Release date:2006-09-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the actin-binding function of missing-in-metastasis
Structure, 15, 2007
2D1L
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BU of 2d1l by Molmil
Structure of F-actin binding domain IMD of MIM (Missing In Metastasis)
Descriptor: Metastasis suppressor protein 1
Authors:Lee, S.H, Kerff, F, Chereau, D, Ferron, F, Dominguez, R.
Deposit date:2005-08-27
Release date:2006-09-12
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for the actin-binding function of missing-in-metastasis
Structure, 15, 2007
2EYN
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BU of 2eyn by Molmil
Crystal structure of the actin-binding domain of human alpha-actinin 1 at 1.8 Angstrom resolution
Descriptor: Alpha-actinin 1
Authors:Borrego-Diaz, E, Kerff, F, Lee, S.H, Ferron, F, Li, Y, Dominguez, R.
Deposit date:2005-11-09
Release date:2006-08-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the actin-binding domain of alpha-actinin 1: Evaluating two competing actin-binding models.
J.Struct.Biol., 155, 2006
2EYI
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BU of 2eyi by Molmil
Crystal structure of the actin-binding domain of human alpha-actinin 1 at 1.7 Angstrom resolution
Descriptor: Alpha-actinin 1
Authors:Borrego-Diaz, E, Kerff, F, Lee, S.H, Ferron, F, Li, Y, Dominguez, R.
Deposit date:2005-11-09
Release date:2006-08-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the actin-binding domain of alpha-actinin 1: Evaluating two competing actin-binding models.
J.Struct.Biol., 155, 2006
4Z8G
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BU of 4z8g by Molmil
Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2 (TL1 ABS2)
Descriptor: NICKEL (II) ION, Tropomodulin-1, Leiomodin-1 chimera (TP1 ABS2)
Authors:Boczkowska, M, Rebowski, G, Dominguez, R.
Deposit date:2015-04-08
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
4Z79
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BU of 4z79 by Molmil
Leiomodin-1 Actin-Binding Site 2 (ABS2)
Descriptor: CHLORIDE ION, GLYCEROL, Leiomodin-1 Actin-Binding Site 2 (ABS2), ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2015-04-06
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
4Z94
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BU of 4z94 by Molmil
Actin Complex With a Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2015-04-09
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015

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