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5V3P
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BU of 5v3p by Molmil
Human A20 OTU domain (I325N) with acetamidylated C103
Descriptor: Tumor necrosis factor alpha-induced protein 3
Authors:Langley, D.B, Christ, D, Grey, S.
Deposit date:2017-03-07
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Nat.Immunol., 20, 2019
6DSI
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BU of 6dsi by Molmil
Anti recombinant prolactin receptor scFv
Descriptor: Anti-TN-C scFv
Authors:Langley, D.B, Rouet, R, Christ, D.
Deposit date:2018-06-14
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Anti recombinant prolactin receptor scFv
To Be Published
6DN0
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BU of 6dn0 by Molmil
Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.
Descriptor: FORMIC ACID, Human Variable Heavy Chain of Herceptin containing VH mutation K30D, Human Variable Light Chain of Herceptin containing VL mutation S52D
Authors:Langley, D.B, Roome, B, Christ, D.
Deposit date:2018-06-05
Release date:2019-06-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Retrofitting antibodies with stabilizing mutations
To Be Published
6D9I
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BU of 6d9i by Molmil
Pekin duck egg lysozyme isoform II (DEL-II)
Descriptor: CHLORIDE ION, Lysozyme, MAGNESIUM ION
Authors:Langley, D.B, Christ, D.
Deposit date:2018-04-30
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structure of duck egg lysozyme isoform II (DEL-II).
BMC Struct. Biol., 18, 2018
4QY8
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BU of 4qy8 by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30
Descriptor: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-07-24
Release date:2015-06-03
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.353 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4QXT
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BU of 4qxt by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with FC27-MSP2 14-30
Descriptor: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-07-22
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4R3S
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BU of 4r3s by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 11-23
Descriptor: FV FRAGMENT(MAB6D8) HEAVY CHAIN, FV FRAGMENT(MAB6D8) LIGHT CHAIN, Merozoite surface protein
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-08-18
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate
Sci Rep, 5, 2015
4QYO
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BU of 4qyo by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 14-22
Descriptor: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-07-24
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.208 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
5TBD
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BU of 5tbd by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222
Descriptor: Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2
Authors:Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S.
Deposit date:2016-09-12
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.
J. Mol. Biol., 429, 2017
5VJO
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BU of 5vjo by Molmil
Complex between HyHEL10 Fab fragment heavy chain mutant I29F and Pekin duck egg lysozyme isoform I (DEL-I)
Descriptor: CHLORIDE ION, HyHEL10 heavy chain Fab fragment carrying I29F mutation., HyHEL10 light chain Fab fragment, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2017-04-19
Release date:2018-04-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
Science, 360, 2018
4K28
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BU of 4k28 by Molmil
2.15 Angstrom resolution crystal structure of a shikimate dehydrogenase family protein from Pseudomonas putida KT2440 in complex with NAD+
Descriptor: MANGANESE (II) ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ...
Authors:Garcia, C, Peek, J, Petit, P, Christendat, D.
Deposit date:2013-04-08
Release date:2013-04-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Insights into the function of RifI2: structural and biochemical investigation of a new shikimate dehydrogenase family protein.
Biochim.Biophys.Acta, 1834, 2013
3BPX
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BU of 3bpx by Molmil
Crystal Structure of MarR
Descriptor: 2-HYDROXYBENZOIC ACID, SODIUM ION, Transcriptional regulator
Authors:Saridakis, V, Shahinas, D, Xu, X, Christendat, D.
Deposit date:2007-12-19
Release date:2008-05-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum.
J.Mol.Biol., 377, 2008
3BPV
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BU of 3bpv by Molmil
Crystal Structure of MarR
Descriptor: Transcriptional regulator
Authors:Saridakis, V, Shahinas, D, Xu, X, Christendat, D.
Deposit date:2007-12-19
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum.
J.Mol.Biol., 377, 2008
2G5C
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BU of 2g5c by Molmil
Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, prephenate dehydrogenase
Authors:Sun, W, Singh, S, Zhang, R, Turnbull, J.L, Christendat, D.
Deposit date:2006-02-22
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus: Insights into the Catalytic Mechanism
J.Biol.Chem., 281, 2006
2GPT
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BU of 2gpt by Molmil
Crystal structure of Arabidopsis Dehydroquinate dehydratase-shikimate dehydrogenase in complex with tartrate and shikimate
Descriptor: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-dehydroquinate dehydratase/ shikimate 5-dehydrogenase, L(+)-TARTARIC ACID, ...
Authors:Singh, S.A, Christendat, D.
Deposit date:2006-04-18
Release date:2006-06-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Arabidopsis dehydroquinate dehydratase-shikimate dehydrogenase and implications for metabolic channeling in the shikimate pathway
Biochemistry, 45, 2006
1KUU
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BU of 1kuu by Molmil
CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD
Descriptor: conserved protein
Authors:Saridakis, V, Christendat, D, Thygesen, A, Arrowsmith, C.H, Edwards, A.M, Pai, E.F.
Deposit date:2002-01-22
Release date:2002-05-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD
PROTEINS: STRUCT.,FUNCT.,GENET., 48, 2002
5HMQ
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BU of 5hmq by Molmil
xylose isomerase-like TIM barrel/4-hydroxyphenylpyruvate dioxygenase fusion protein
Descriptor: 4-hydroxyphenylpyruvate dioxygenase, MAGNESIUM ION
Authors:Peek, J, Christendat, D.
Deposit date:2016-01-16
Release date:2016-10-19
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.371 Å)
Cite:Structure of a putative xylose isomerase-like TIM barrel/4-hydroxyphenylpyruvate dioxygenase fusion protein from Pseudomonas putida at 2.4 Angstroms resolution.
To Be Published
3GGP
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BU of 3ggp by Molmil
Crystal structure of prephenate dehydrogenase from A. aeolicus in complex with hydroxyphenyl propionate and NAD+
Descriptor: CHLORIDE ION, HYDROXYPHENYL PROPIONIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Sun, W, Shahinas, D, Kimber, M.S, Christendat, D.
Deposit date:2009-03-01
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
3GGG
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BU of 3ggg by Molmil
The crystal structure of A. aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Prephenate dehydrogenase, TYROSINE
Authors:Sun, W, Shahinas, D, Christendat, D.
Deposit date:2009-02-27
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
3GGO
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BU of 3ggo by Molmil
Crystal structure of prephenate dehydrogenase from A. aeolicus with HPP and NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, Prephenate dehydrogenase
Authors:Sun, W, Shahinas, D, Christendat, D.
Deposit date:2009-03-01
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
1K3R
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BU of 1k3r by Molmil
Crystal Structure of the Methyltransferase with a Knot from Methanobacterium thermoautotrophicum
Descriptor: conserved protein MT0001
Authors:Zarembinski, T.I, Kim, Y, Peterson, K, Christendat, D, Dharamsi, A, Arrowsmith, C.H, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2001-10-03
Release date:2002-05-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Deep trefoil knot implicated in RNA binding found in an archaebacterial protein.
Proteins, 50, 2003
1L3I
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BU of 1l3i by Molmil
MT0146, THE PRECORRIN-6Y METHYLTRANSFERASE (CBIT) HOMOLOG FROM M. THERMOAUTOTROPHICUM, ADOHCY BINARY COMPLEX
Descriptor: Precorrin-6y methyltransferase/putative decarboxylase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Keller, J.P, Smith, P.M, Benach, J, Christendat, D, deTitta, G, Hunt, J.F.
Deposit date:2002-02-27
Release date:2002-11-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Crystal Structure of Mt0146/CbiT Suggests that the Putative Precorrin-8W Decarboxylase is a Methyltransferase
Structure, 10, 2002
1L3B
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BU of 1l3b by Molmil
MT0146, THE PRECORRIN-6Y METHYLTRANSFERASE (CBIT) HOMOLOG FROM M. THERMOAUTOTROPHICUM, C2 SPACEGROUP W/ LONG CELL
Descriptor: Precorrin-6y methyltransferase/putative decarboxylase
Authors:Keller, J.P, Smith, P.M, Benach, J, Christendat, D, deTitta, G, Hunt, J.F.
Deposit date:2002-02-26
Release date:2002-11-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The Crystal Structure of Mt0146/CbiT Suggests that the Putative Precorrin-8W Decarboxylase is a Methyltransferase
Structure, 10, 2002
1KYT
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BU of 1kyt by Molmil
Crystal Structure of Thermoplasma acidophilum 0175 (APC014)
Descriptor: CALCIUM ION, hypothetical protein TA0175
Authors:Kim, Y, Joachimiak, A, Edwards, A, Xu, X, Pennycooke, M, Gu, J, Cheung, F, Christendat, D, Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-02-05
Release date:2003-01-21
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Thermoplasma acidophilum 0175 (APC014)
To be published
1LXJ
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BU of 1lxj by Molmil
X-RAY STRUCTURE OF YBL001c NORTHEAST STRUCTURAL GENOMICS (NESG) CONSORTIUM TARGET YTYst72
Descriptor: HYPOTHETICAL 11.5KDA PROTEIN IN HTB2-NTH2 INTERGENIC REGION, SULFATE ION
Authors:Tao, X, Khayat, R, Christendat, D, Savchenko, A, Xu, X, Edwards, A, Arrowsmith, C.H, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-06-05
Release date:2003-07-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:CRYSTAL STRUCTURES OF MTH1187 AND ITS YEAST ORTHOLOG YBL001C
Proteins, 52, 2003

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