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Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-108
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ...
Authors:	Regan, M.C, Furukawa, H.
Deposit date:	2023-02-01
Release date:	2023-03-01
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. Acs Chem Neurosci, 14, 2023

Crystal structure of the NMDA receptor GluN1 ligand binding domain in complex with 1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one
Descriptor:	1-sulfanyl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one, GLYCEROL, Glutamate receptor ionotropic, ...
Authors:	Steffensen, T.B, Tabrizi, F.M, Gajhede, M, Kastrup, J.S.
Deposit date:	2013-04-27
Release date:	2013-10-09
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. J.Biol.Chem., 288, 2013

Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam
Descriptor:	1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2
Authors:	Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M.
Deposit date:	2005-08-04
Release date:	2005-10-25
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Mechanism of positive allosteric modulators acting on AMPA receptors. J.Neurosci., 25, 2005