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8IDF
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BU of 8idf by Molmil
Crystal structure of human TUT1 complexed with U6 snRNA
Descriptor: RNA (53-MER), Speckle targeted PIP5K1A-regulated poly(A) polymerase, ZINC ION
Authors:Yamashita, S, Tomita, K.
Deposit date:2023-02-13
Release date:2023-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Mechanism of U6 snRNA oligouridylation by human TUT1.
Nat Commun, 14, 2023
8XHR
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BU of 8xhr by Molmil
Crystal structure of Mycobacterium tuberculosis MenT3 bound with CTP
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Nucleotidyl transferase AbiEii/AbiGii toxin family protein
Authors:Liu, J, Yashiro, Y, Tomita, K.
Deposit date:2023-12-18
Release date:2024-02-28
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3.
Nucleic Acids Res., 52, 2024
3H39
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BU of 3h39 by Molmil
The complex structure of CCA-adding enzyme with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, TRNA nucleotidyl transferase-related protein
Authors:Toh, Y, Tomita, K.
Deposit date:2009-04-16
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.854 Å)
Cite:Mechanism for the definition of elongation and termination by the class II CCA-adding enzyme
Embo J., 28, 2009
3H3A
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BU of 3h3a by Molmil
The complex structure of CCA-adding enzyme with CTP
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, TRNA nucleotidyl transferase-related protein
Authors:Toh, Y, Tomita, K.
Deposit date:2009-04-16
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Mechanism for the definition of elongation and termination by the class II CCA-adding enzyme
Embo J., 28, 2009
3AQK
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BU of 3aqk by Molmil
Structure of bacterial protein (apo form I)
Descriptor: Poly(A) polymerase
Authors:Toh, Y, Takeshita, D, Tomita , K.
Deposit date:2010-11-09
Release date:2011-02-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Mechanism for the alteration of the substrate specificities of template-independent RNA polymerases
Structure, 19, 2011
3AQN
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BU of 3aqn by Molmil
Complex structure of bacterial protein (apo form II)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Poly(A) polymerase
Authors:Toh, Y, Takeshita, D, Tomita , K.
Deposit date:2010-11-09
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mechanism for the alteration of the substrate specificities of template-independent RNA polymerases
Structure, 19, 2011
3AQL
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BU of 3aql by Molmil
Structure of bacterial protein (apo form II)
Descriptor: GLYCEROL, MAGNESIUM ION, Poly(A) polymerase
Authors:Toh, Y, Takeshita, D, Tomita , K.
Deposit date:2010-11-09
Release date:2011-02-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanism for the alteration of the substrate specificities of template-independent RNA polymerases
Structure, 19, 2011
4WC3
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BU of 4wc3 by Molmil
Structure of tRNA-processing enzyme complex 1
Descriptor: Poly A polymerase, RNA 76-mer
Authors:Yamashita, S, Tomita, K.
Deposit date:2014-09-04
Release date:2015-04-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
4WC0
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BU of 4wc0 by Molmil
tRNA-processing enzyme with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Poly A polymerase
Authors:Yamashita, S, Tomita, K.
Deposit date:2014-09-04
Release date:2015-04-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
4WC2
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BU of 4wc2 by Molmil
Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, Poly A polymerase, ...
Authors:Yamashita, S, Tomita, K.
Deposit date:2014-09-04
Release date:2015-04-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
4WC1
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BU of 4wc1 by Molmil
Structure of tRNA-processing enzyme with CTP
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Poly A polymerase
Authors:Yamashita, S, Tomita, K.
Deposit date:2014-09-04
Release date:2015-04-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
4WC7
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BU of 4wc7 by Molmil
Structure of tRNA-processing enzyme complex 5
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Poly A polymerase, RNA (75-MER)
Authors:Yamashita, S, Tomita, K.
Deposit date:2014-09-04
Release date:2015-04-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
4X0A
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BU of 4x0a by Molmil
Structure of tRNA-processing enzyme complex 6
Descriptor: Poly A polymerase, RNA (73-MER)
Authors:Yamashita, S, Tomita, K.
Deposit date:2014-11-21
Release date:2015-04-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.505 Å)
Cite:Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
4X0B
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BU of 4x0b by Molmil
Structure of tRNA-processing enzyme complex 7
Descriptor: Poly A polymerase, RNA (77-MER)
Authors:Yamashita, S, Tomita, K.
Deposit date:2014-11-21
Release date:2015-04-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
6LMI
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BU of 6lmi by Molmil
Crystal structure of HIV-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-6-methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid
Descriptor: (2S)-2-[2-(3,4-dihydro-2H-chromen-6-yl)-4-(3,4-dimethylphenyl)-3,6-dimethyl-5-(methylsulfonylamino)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, Integrase catalytic, ...
Authors:Sugiyama, S, Iwaki, T, Tamura, Y, Tomita, K, Matsuoka, E, Arita, S, Seki, T, Yoshinaga, T, Kawasuji, T.
Deposit date:2019-12-25
Release date:2020-09-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold.
Bioorg.Med.Chem., 28, 2020
6LMQ
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BU of 6lmq by Molmil
Crystal structure of HIV-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)-6-methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid
Descriptor: (2S)-2-[2-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)-4-(3,4-dimethylphenyl)-3,6-dimethyl-5-(methylsulfonylamino)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, Integrase catalytic, SULFATE ION, ...
Authors:Sugiyama, S, Iwaki, T, Tamura, Y, Tomita, K, Matsuoka, E, Arita, S, Seki, T, Yoshinaga, T, Kawasuji, T.
Deposit date:2019-12-26
Release date:2020-09-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold.
Bioorg.Med.Chem., 28, 2020
6M1U
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BU of 6m1u by Molmil
Crystal structure of the vertebrate conserved region (VCR) of human METTL16
Descriptor: RNA N6-adenosine-methyltransferase METTL16,RNA N6-adenosine-methyltransferase METTL16
Authors:Aoyama, T, Yamashita, S, Tomita, K.
Deposit date:2020-02-26
Release date:2020-04-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.791 Å)
Cite:Mechanistic insights into m6A modification of U6 snRNA by human METTL16.
Nucleic Acids Res., 48, 2020
6L8U
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BU of 6l8u by Molmil
Crystal structure of human BCDIN3D in complex with SAH
Descriptor: RNA 5'-monophosphate methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Liu, Y, Martinez, A, Yamashita, S, Tomita, K.
Deposit date:2019-11-07
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.925 Å)
Cite:Crystal structure of human cytoplasmic tRNAHis-specific 5'-monomethylphosphate capping enzyme.
Nucleic Acids Res., 48, 2020
5Y0R
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BU of 5y0r by Molmil
Crystal structure of Thermotoga maritima TmcAL (apo, form I)
Descriptor: TmTmcAL(SeMet)
Authors:Yamashita, S, Tomita, K.
Deposit date:2017-07-18
Release date:2018-07-18
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis.
Nat. Chem. Biol., 14, 2018
5Y0N
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BU of 5y0n by Molmil
Crystal structure of Bacillus subtilis TmcAL bound with ATP (SeMet derivative)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, UPF0348 protein B4417_3650
Authors:Yamashita, S, Tomita, K.
Deposit date:2017-07-18
Release date:2018-07-18
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis.
Nat. Chem. Biol., 14, 2018
3AGP
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BU of 3agp by Molmil
Structure of viral polymerase form I
Descriptor: CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ...
Authors:Takeshita, D, Tomita, K.
Deposit date:2010-04-06
Release date:2010-09-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts
Proc.Natl.Acad.Sci.USA, 107, 2010
3AGQ
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BU of 3agq by Molmil
Structure of viral polymerase form II
Descriptor: Elongation factor Ts, Elongation factor Tu 1, LINKER, ...
Authors:Takeshita, D, Tomita, K.
Deposit date:2010-04-06
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts
Proc.Natl.Acad.Sci.USA, 107, 2010
5Y0Q
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BU of 5y0q by Molmil
Crystal structure of BsTmcAL bound with AMPCPP
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, UPF0348 protein B4417_3650
Authors:Yamashita, S, Tomita, K.
Deposit date:2017-07-18
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis.
Nat. Chem. Biol., 14, 2018
3AVT
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BU of 3avt by Molmil
Structure of viral RNA polymerase complex 1
Descriptor: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ...
Authors:Takeshita, D, Tomita, K.
Deposit date:2011-03-08
Release date:2012-01-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.607 Å)
Cite:Molecular basis for RNA polymerization by Q beta replicase
Nat.Struct.Mol.Biol., 19, 2012
5Y0O
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BU of 5y0o by Molmil
Crystal structure of apo BsTmcAL
Descriptor: UPF0348 protein B4417_3650
Authors:Yamashita, S, Tomita, K.
Deposit date:2017-07-18
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis.
Nat. Chem. Biol., 14, 2018

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