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CryoEM structure of DH270.6-CH848.0526.25
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.0526.25 gp120, CH848.0526.25 gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-01
Release date:	2023-04-19
Last modified:	2023-05-31
Method:	ELECTRON MICROSCOPY (3.9 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SB2

CryoEM structure of DH270.I2-CH848.10.17
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-02
Release date:	2023-04-19
Last modified:	2023-05-31
Method:	ELECTRON MICROSCOPY (3.5 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SB0

CryoEM structure of DH270.I4.6-CH848.10.17
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-02
Release date:	2023-04-19
Last modified:	2023-05-31
Method:	ELECTRON MICROSCOPY (4.2 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SB1

CryoEM structure of DH270.I3-CH848.10.17
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17.SOSIP gp41, ...
Authors:	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:	2023-04-02
Release date:	2023-04-19
Last modified:	2023-05-31
Method:	ELECTRON MICROSCOPY (4.3 Å)
Cite:	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8CSA

Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 3-RBD-Down conformation (S-GSAS-D614G-K417N-E484K-N501Y)
Descriptor:	Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2022-05-12
Release date:	2022-07-20
Last modified:	2024-01-31
Method:	ELECTRON MICROSCOPY (3.84 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity Science, 2021

6VTU

DH717.1 Fab monomer in complex with man9 glycan
Descriptor:	DH717.1 heavy chain, DH717.1 light chain, GLYCEROL, ...
Authors:	Fera, D, Bronkema, N.
Deposit date:	2020-02-13
Release date:	2020-12-30
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.61 Å)
Cite:	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7SG4

Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-10-04
Release date:	2021-11-10
Last modified:	2022-02-09
Method:	ELECTRON MICROSCOPY (3.43 Å)
Cite:	A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice. Sci Transl Med, 14, 2022

6X2A

SARS-CoV-2 u1S2q 1-RBD Up Spike Protein Trimer
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2020-05-20
Release date:	2020-05-27
Last modified:	2021-08-04
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6X29

SARS-CoV-2 rS2d Down State Spike Protein Trimer
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2020-05-20
Release date:	2020-05-27
Last modified:	2020-10-21
Method:	ELECTRON MICROSCOPY (2.7 Å)
Cite:	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6X2B

SARS-CoV-2 u1S2q 2-RBD Up Spike Protein Trimer
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2020-05-20
Release date:	2020-05-27
Last modified:	2021-08-04
Method:	ELECTRON MICROSCOPY (3.6 Å)
Cite:	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6X2C

SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer
Descriptor:	Spike glycoprotein
Authors:	Henderson, R, Acharya, P.
Deposit date:	2020-05-20
Release date:	2020-05-27
Last modified:	2021-07-07
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6XRJ

Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
Descriptor:	DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
Authors:	Manne, K, Nicely, N.I, Acharya, P.
Deposit date:	2020-07-13
Release date:	2020-12-30
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (3.15 Å)
Cite:	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7LYK

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 2-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.65 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYQ

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.34 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYL

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.72 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYO

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.32 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYP

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (4.05 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYN

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.32 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7KDI

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer fully cleaved by furin without the P986-P987 stabilizing mutations (S-RRAR-D614G)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2020-10-08
Release date:	2020-11-04
Last modified:	2021-03-31
Method:	ELECTRON MICROSCOPY (3.26 Å)
Cite:	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDH

SARS-CoV-2 RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2020-10-08
Release date:	2020-11-04
Last modified:	2021-03-31
Method:	ELECTRON MICROSCOPY (3.33 Å)
Cite:	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDG

SARS-CoV-2 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2020-10-08
Release date:	2020-11-04
Last modified:	2021-03-31
Method:	ELECTRON MICROSCOPY (3.01 Å)
Cite:	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDL

SARS-CoV-2 D614G 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2020-10-08
Release date:	2020-11-04
Last modified:	2021-03-31
Method:	ELECTRON MICROSCOPY (2.96 Å)
Cite:	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDJ

SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer fully cleaved by furin without the P986-P987 stabilizing mutations (S-RRAR-D614G)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2020-10-08
Release date:	2020-11-04
Last modified:	2021-03-31
Method:	ELECTRON MICROSCOPY (3.49 Å)
Cite:	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDK

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2020-10-08
Release date:	2020-11-04
Last modified:	2021-03-31
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KEB

SARS-CoV-2 D614G 1RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2020-10-10
Release date:	2020-11-04
Last modified:	2021-03-31
Method:	ELECTRON MICROSCOPY (3.48 Å)
Cite:	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

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