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6S9L
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BU of 6s9l by Molmil
Designed Armadillo Repeat protein Lock1 bound to (KR)4KLSF target
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, KR4KLSF Lock1, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-LEU-SER-PHE
Authors:Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A.
Deposit date:2019-07-15
Release date:2020-02-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
6S9O
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BU of 6s9o by Molmil
Designed Armadillo Repeat protein internal Lock1 fused to target peptide KRKRKLKFKR
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, designed Armadillo repeat protein with internal Lock1 fused to target peptide KRKRKLKFKR
Authors:Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A.
Deposit date:2019-07-15
Release date:2020-02-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
6S9P
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BU of 6s9p by Molmil
Designed Armadillo Repeat protein internal Lock2 fused to target peptide KRKAKITWKR
Descriptor: 1,2-ETHANEDIOL, internal Lock2 fused to target peptide KRKAKITWKR
Authors:Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A.
Deposit date:2019-07-15
Release date:2020-02-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
6S9M
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BU of 6s9m by Molmil
Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKITW
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKITW, ...
Authors:Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A.
Deposit date:2019-07-15
Release date:2020-02-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
3MOR
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BU of 3mor by Molmil
Crystal structure of Cathepsin B from Trypanosoma Brucei
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Cathepsin B-like cysteine protease, ...
Authors:Cupelli, K, Stehle, T.
Deposit date:2010-04-23
Release date:2011-11-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:In vivo protein crystallization opens new routes in structural biology.
Nat.Methods, 9, 2012
4FE1
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BU of 4fe1 by Molmil
Improving the Accuracy of Macromolecular Structure Refinement at 7 A Resolution
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
Authors:Fromme, R, Adams, P.D, Fromme, P, Levitt, M, Schroeder, G.F, Brunger, A.T.
Deposit date:2012-05-29
Release date:2012-08-15
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (4.9228 Å)
Cite:Improving the accuracy of macromolecular structure refinement at 7 A resolution.
Structure, 20, 2012
8U29
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BU of 8u29 by Molmil
Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ...
Authors:Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-05
Release date:2023-12-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
8U0T
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BU of 8u0t by Molmil
PRD-0038 RBD bound to Rhinolophus alcyone ACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, PRD-0038, ...
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-08-29
Release date:2023-12-06
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
9DB3
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BU of 9db3 by Molmil
Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus. FCoV-23 S long with Do in swung-out conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FCoV-23 S long with Do in swung-out conformation, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-08-23
Release date:2025-07-09
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics
Nature, 2025
9DBZ
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BU of 9dbz by Molmil
Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus. FCoV-23 S long with Do in mixed conformations (global refinement).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITOLEIC ACID, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-08-24
Release date:2025-07-09
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics
Nature, 2025
9DAZ
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BU of 9daz by Molmil
Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus. Complex of fAPN with FCoV-23 RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-08-23
Release date:2025-07-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics
Nature, 2025
9DB1
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BU of 9db1 by Molmil
Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus. FCoV-23 S Do in proximal conformation (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-08-23
Release date:2025-07-09
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics
Nature, 2025
9DBE
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BU of 9dbe by Molmil
Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus. FCoV-23 S long domain 0 in swung-out conformation (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-08-23
Release date:2025-07-09
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics
Nature, 2025
9DB0
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BU of 9db0 by Molmil
Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus. FCoV-23 S short
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITOLEIC ACID, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-08-23
Release date:2025-07-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics
Nature, 2025
8VQ9
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BU of 8vq9 by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQB
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BU of 8vqb by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQA
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BU of 8vqa by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8F54
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BU of 8f54 by Molmil
Top-down design of protein architectures with reinforcement learning
Descriptor: RC_I_1
Authors:Borst, A.J, Baker, D.
Deposit date:2022-11-11
Release date:2023-05-10
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
8F4X
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BU of 8f4x by Molmil
Top-down design of protein architectures with reinforcement learning
Descriptor: RC_I_1-H11
Authors:Borst, A.J, Baker, D.
Deposit date:2022-11-11
Release date:2023-05-10
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
8F53
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BU of 8f53 by Molmil
Top-down design of protein architectures with reinforcement learning
Descriptor: RC_I_2
Authors:Borst, A.J, Baker, D.
Deposit date:2022-11-11
Release date:2023-05-10
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
7P3I
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BU of 7p3i by Molmil
Crystal structure of human CD40/TNFRSF5 in complex with the anti-CD40 DARPin protein
Descriptor: Darpin, SODIUM ION, Tumor necrosis factor receptor superfamily member 5
Authors:Malvezzi, F, Mangold, S, Hospodarsch, T, Reichen, C, Iss, C, Lammens, A, Krapp, S, Domke, C.
Deposit date:2021-07-07
Release date:2022-04-06
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:A Multispecific Anti-CD40 DARPin Construct Induces Tumor-Selective CD40 Activation and Tumor Regression.
Cancer Immunol Res, 10, 2022
2RU4
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BU of 2ru4 by Molmil
Designed Armadillo Repeat Protein Self-ASsembled Complex (YIIM2-MAII)
Descriptor: Armadillo Repeat Protein, C-terminal fragment, MAII, ...
Authors:Zerbe, O, Christen, M.T, Plueckthun, A, Watson, R.P.
Deposit date:2013-11-22
Release date:2014-07-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Spontaneous self-assembly of engineered armadillo repeat protein fragments into a folded structure
Structure, 22, 2014
2RU5
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BU of 2ru5 by Molmil
Designed Armadillo Repeat Protein Fragment (MAII)
Descriptor: Armadillo repeat protein C-terminal fragment
Authors:Zerbe, O, Christen, M.T, Plueckthun, A, Watson, R.P.
Deposit date:2013-11-23
Release date:2014-07-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Spontaneous self-assembly of engineered armadillo repeat protein fragments into a folded structure
Structure, 22, 2014
2N0X
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BU of 2n0x by Molmil
Three dimensional structure of EPI-X4, a human albumin-derived peptide that regulates innate immunity through the CXCR4/CXCL12 chemotactic axis and antagonizes HIV-1 entry
Descriptor: Serum albumin
Authors:Perez-Castells, J, Canales, A, Jimenez-Barbero, J, Gimenez-Gallego, G.
Deposit date:2015-03-18
Release date:2015-04-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Discovery and characterization of an endogenous CXCR4 antagonist.
Cell Rep, 11, 2015
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