3F1N
| Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with internally bound ethylene glycol. | Descriptor: | 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | Authors: | Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H. | Deposit date: | 2008-10-28 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.479 Å) | Cite: | Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor. Proc.Natl.Acad.Sci.USA, 106, 2009
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3H7W
| Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains with the artificial ligand THS017 | Descriptor: | 2-nitro-N-(thiophen-3-ylmethyl)-4-(trifluoromethyl)aniline, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | Authors: | Key, J.M, Scheuermann, T.H, Anderson, P.C, Daggett, V, Gardner, K.H. | Deposit date: | 2009-04-28 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B J.Am.Chem.Soc., 131, 2009
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3H82
| Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains with the artificial ligand THS020 | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(furan-2-ylmethyl)-2-nitro-4-(trifluoromethyl)aniline | Authors: | Key, J.M, Scheuermann, T.H, Anderson, P.C, Daggett, V, Gardner, K.H. | Deposit date: | 2009-04-28 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B J.Am.Chem.Soc., 131, 2009
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4PKY
| ARNT/HIF transcription factor/coactivator complex | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, SULFATE ION, ... | Authors: | Tomchick, D.R, Partch, C.L, Gardner, K.H. | Deposit date: | 2014-05-15 | Release date: | 2015-02-11 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Coiled-coil Coactivators Play a Structural Role Mediating Interactions in Hypoxia-inducible Factor Heterodimerization. J.Biol.Chem., 290, 2015
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4R38
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4R39
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4R3A
| Erythrobacter litoralis EL346 blue-light activated histidine kinase | Descriptor: | Blue-light-activated histidine kinase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Tomchick, D.R, Rivera-Cancel, G, Gardner, K.H. | Deposit date: | 2014-08-14 | Release date: | 2014-12-03 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation. Proc.Natl.Acad.Sci.USA, 111, 2014
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4LPZ
| ARNT transcription factor/coactivator complex | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Transforming acidic coiled-coil-containing protein 3 | Authors: | Guo, Y, Scheuermann, T.H, Gardner, K.H. | Deposit date: | 2013-07-16 | Release date: | 2014-07-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization. J.Biol.Chem., 290, 2015
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1P97
| NMR structure of the C-terminal PAS domain of HIF2a | Descriptor: | Endothelial PAS domain protein 1 | Authors: | Erbel, P.J, Card, P.B, Karakuzu, O, Bruick, R.K, Gardner, K.H. | Deposit date: | 2003-05-09 | Release date: | 2004-01-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis for PAS domain heterodimerization in the basic helix-loop-helix-PAS transcription factor hypoxia-inducible factor. Proc.Natl.Acad.Sci.USA, 100, 2003
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2KB2
| BlrP1 BLUF | Descriptor: | BlrP1, FLAVIN MONONUCLEOTIDE | Authors: | Wu, Q, Gardner, K.H. | Deposit date: | 2008-11-19 | Release date: | 2009-04-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and insight into blue light-induced changes in the BlrP1 BLUF domain Biochemistry, 48, 2009
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3P7N
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3MZI
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