1OEU
 
 | | Oxidation state of protein tyrosine phosphatase 1B | | Descriptor: | MAGNESIUM ION, PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1 | | Authors: | van Montfort, R.L.M, Congreve, M, Tisi, D, Carr, R, Jhoti, H. | | Deposit date: | 2003-03-31 | | Release date: | 2003-06-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B.
Nature, 423, 2003
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1PTY
 | | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO PHOSPHOTYROSINE MOLECULES | | Descriptor: | MAGNESIUM ION, O-PHOSPHOTYROSINE, PROTEIN TYROSINE PHOSPHATASE 1B | | Authors: | Zhao, Y, Puius, Y.A, Sullivan, M, Lawrence, D, Almo, S.C, Zhang, Z.-Y. | | Deposit date: | 1997-01-16 | | Release date: | 1998-01-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.
Proc.Natl.Acad.Sci.USA, 94, 1997
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3HB1
 | | Crystal structure of ed-eya2 complexed with Alf3 | | Descriptor: | ALUMINUM FLUORIDE, Eyes absent homolog 2 (Drosophila), MAGNESIUM ION | | Authors: | Jung, S.K, Jeong, D.G, Ryu, S.E, Kim, S.J. | | Deposit date: | 2009-05-03 | | Release date: | 2009-12-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Faseb J., 24, 2010
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3HB0
 | | Structure of edeya2 complexed with bef3 | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Eyes absent homolog 2 (Drosophila), MAGNESIUM ION | | Authors: | Jung, S.K, Jeong, D.G, Ryu, S.E, Kim, S.J. | | Deposit date: | 2009-05-03 | | Release date: | 2009-12-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Faseb J., 24, 2010
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1SUG
 | | 1.95 A structure of apo protein tyrosine phosphatase 1B | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Protein-tyrosine phosphatase, ... | | Authors: | Pedersen, A.K, Peters, G.H, Moller, K.B, Iversen, L.F, Kastrup, J.S. | | Deposit date: | 2004-03-26 | | Release date: | 2004-09-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Water-molecule network and active-site flexibility of apo protein tyrosine phosphatase 1B.
Acta Crystallogr.,Sect.D, 60, 2004
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1BZC
 | | HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH TPI | | Descriptor: | 4-CARBAMOYL-4-{[6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBONYL]-AMINO}-BUTYRIC ACID, PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE) | | Authors: | Groves, M.R, Yao, Z.J, Jr Burke, T.R, Barford, D. | | Deposit date: | 1998-10-27 | | Release date: | 1999-02-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
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1BZH
 | | Cyclic peptide inhibitor of human PTP1B | | Descriptor: | PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B INHIBITOR), PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B) | | Authors: | Groves, M.R, Yao, Z.J, Burke Jr, T.R, Barford, D. | | Deposit date: | 1998-10-28 | | Release date: | 1999-02-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
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