7YVR
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![BU of 7yvr by Molmil](/molmil-images/mine/7yvr) | Crystal Structure of L-Threonine Aldolase from Neptunomonas marina | Descriptor: | GLYCEROL, L-threonine aldolase | Authors: | He, Y.Z, Wang, J, Yan, W.P, Zhang, Y, Feng, Y. | Deposit date: | 2022-08-19 | Release date: | 2023-05-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery and Engineering of the L-Threonine Aldolase from Neptunomonas marine for the Efficient Synthesis of beta-Hydroxy-alpha-amino Acids via C-C Formation Acs Catalysis, 2023
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8HDS
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![BU of 8hds by Molmil](/molmil-images/mine/8hds) | Cyanophage Pam3 portal-adaptor | Descriptor: | Pam3 adaptor protein, Pam3 portal protein | Authors: | Yang, F, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2022-11-06 | Release date: | 2023-01-18 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Fine structure and assembly pattern of a minimal myophage Pam3. Proc.Natl.Acad.Sci.USA, 120, 2023
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8HDT
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![BU of 8hdt by Molmil](/molmil-images/mine/8hdt) | |
8HDW
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![BU of 8hdw by Molmil](/molmil-images/mine/8hdw) | Cyanophage Pam3 Sheath-tube | Descriptor: | Pam3 sheath protein, pam3 tube | Authors: | Yang, F, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2022-11-06 | Release date: | 2023-01-18 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Fine structure and assembly pattern of a minimal myophage Pam3. Proc.Natl.Acad.Sci.USA, 120, 2023
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8HDR
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![BU of 8hdr by Molmil](/molmil-images/mine/8hdr) | Cyanophage Pam3 neck | Descriptor: | Pam3 adaptor protein, Pam3 connector protein, Pam3 sheath protein, ... | Authors: | Yang, F, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2022-11-06 | Release date: | 2023-02-01 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Fine structure and assembly pattern of a minimal myophage Pam3. Proc.Natl.Acad.Sci.USA, 120, 2023
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5H3R
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![BU of 5h3r by Molmil](/molmil-images/mine/5h3r) | Crystal Structure of mutant MarR C80S from E.coli complexed with operator DNA | Descriptor: | DNA (5'-D(*CP*AP*TP*AP*CP*TP*TP*GP*CP*CP*TP*GP*GP*GP*CP*AP*AP*TP*AP*TP*T)-3'), DNA (5'-D(*GP*AP*AP*TP*AP*TP*TP*GP*CP*CP*CP*AP*GP*GP*CP*AP*AP*GP*TP*AP*T)-3'), Multiple antibiotic resistance protein MarR | Authors: | Zhu, R, Lou, H, Hao, Z. | Deposit date: | 2016-10-26 | Release date: | 2017-08-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Structural characterization of the DNA-binding mechanism underlying the copper(II)-sensing MarR transcriptional regulator. J. Biol. Inorg. Chem., 22, 2017
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6PPA
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![BU of 6ppa by Molmil](/molmil-images/mine/6ppa) | Crystal structure of the unliganded bromodomain of human BRD7 | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 7, PHOSPHATE ION | Authors: | Chan, A, Karim, M.R, Zhu, J, Schonbrunn, E. | Deposit date: | 2019-07-05 | Release date: | 2020-03-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains. J.Med.Chem., 63, 2020
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3ML9
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![BU of 3ml9 by Molmil](/molmil-images/mine/3ml9) | |
3ML8
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![BU of 3ml8 by Molmil](/molmil-images/mine/3ml8) | |
2E0H
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![BU of 2e0h by Molmil](/molmil-images/mine/2e0h) | |
7RGW
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![BU of 7rgw by Molmil](/molmil-images/mine/7rgw) | |
6XK9
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![BU of 6xk9 by Molmil](/molmil-images/mine/6xk9) | Cereblon in complex with DDB1, CC-90009, and GSPT1 | Descriptor: | 2-(4-chlorophenyl)-N-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)-2,2-difluoroacetamide, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | Authors: | Clayton, T.L, Tran, E.T, Zhu, J, Pagarigan, B.E, Matyskiela, M.E, Chamberlain, P.P. | Deposit date: | 2020-06-25 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.64 Å) | Cite: | CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells. Blood, 137, 2021
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6W7Z
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![BU of 6w7z by Molmil](/molmil-images/mine/6w7z) | RNF12 RING domain in complex with Ube2d2 | Descriptor: | E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Middleton, A.J, Day, C.L. | Deposit date: | 2020-03-19 | Release date: | 2020-05-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. J.Mol.Biol., 432, 2020
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8KHD
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![BU of 8khd by Molmil](/molmil-images/mine/8khd) | The interface structure of Omicron RBD binding to 5817 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817, Light chain of 5817, ... | Authors: | Cao, L, Wang, X. | Deposit date: | 2023-08-21 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain. Cell Rep, 43, 2024
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8KHC
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![BU of 8khc by Molmil](/molmil-images/mine/8khc) | SARS-CoV-2 Omicron spike in complex with 5817 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817 Fab, ... | Authors: | Cao, L, Wang, X. | Deposit date: | 2023-08-21 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain. Cell Rep, 43, 2024
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3HIZ
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![BU of 3hiz by Molmil](/molmil-images/mine/3hiz) | Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Amzel, L.M, Vogelstein, B, Gabelli, S.B, Mandelker, D. | Deposit date: | 2009-05-20 | Release date: | 2009-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Proc.Natl.Acad.Sci.USA, 106, 2009
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3HHM
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![BU of 3hhm by Molmil](/molmil-images/mine/3hhm) | Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin | Descriptor: | (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... | Authors: | Amzel, L.M, Vogelstein, B, Gabelli, S.B, Mandelker, D. | Deposit date: | 2009-05-15 | Release date: | 2009-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Proc.Natl.Acad.Sci.USA, 106, 2009
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3IEJ
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![BU of 3iej by Molmil](/molmil-images/mine/3iej) | Pyrazole-based Cathepsin S Inhibitors with Arylalkynes as P1 Binding Elements | Descriptor: | 2-[3-{4-chloro-3-[(4-chlorophenyl)ethynyl]phenyl}-1-(3-morpholin-4-ylpropyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-2-oxoethanol, Cathepsin S | Authors: | Bembenek, S. | Deposit date: | 2009-07-22 | Release date: | 2009-10-06 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements. Bioorg.Med.Chem.Lett., 19, 2009
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7RTC
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![BU of 7rtc by Molmil](/molmil-images/mine/7rtc) | |
4JBA
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![BU of 4jba by Molmil](/molmil-images/mine/4jba) | |
3NGB
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![BU of 3ngb by Molmil](/molmil-images/mine/3ngb) | |
6W9A
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![BU of 6w9a by Molmil](/molmil-images/mine/6w9a) | RNF12 RING domain in complex with Ube2e2 | Descriptor: | E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 E2, ... | Authors: | Middleton, A.J, Day, C.L. | Deposit date: | 2020-03-22 | Release date: | 2020-05-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. J.Mol.Biol., 432, 2020
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8GN6
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![BU of 8gn6 by Molmil](/molmil-images/mine/8gn6) | Crystallization of Sialidase from Porphyromonas gingivalis | Descriptor: | Sialidase, UNKNOWN LIGAND | Authors: | Dong, W.B. | Deposit date: | 2022-08-23 | Release date: | 2023-04-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and enzymatic characterization of the sialidase SiaPG from Porphyromonas gingivalis. Acta Crystallogr.,Sect.F, 79, 2023
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6BKD
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![BU of 6bkd by Molmil](/molmil-images/mine/6bkd) | Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3D | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3D heavy chain, Fab AR3D light chain, ... | Authors: | Tzarum, N, Wilson, I.A, Law, M. | Deposit date: | 2017-11-08 | Release date: | 2018-12-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies. Sci Adv, 5, 2019
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3LRS
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![BU of 3lrs by Molmil](/molmil-images/mine/3lrs) | Structure of PG16, an antibody with broad and potent neutralization of HIV-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PG-16 Heavy Chain Fab, PG-16 Light Chain Fab | Authors: | Pancera, M, Kwong, P.D. | Deposit date: | 2010-02-11 | Release date: | 2010-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1. J.Virol., 84, 2010
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