6O5M
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![BU of 6o5m by Molmil](/molmil-images/mine/6o5m) | Tubulin-RB3_SLD-TTL in complex with compound 10bb | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | Deposit date: | 2019-03-04 | Release date: | 2019-07-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin. J.Med.Chem., 62, 2019
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6IEB
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![BU of 6ieb by Molmil](/molmil-images/mine/6ieb) | Structure of RVFV Gn and human monoclonal antibody R15 | Descriptor: | NSmGnGc, R15 H chain, R15 L chain | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | Deposit date: | 2018-09-13 | Release date: | 2019-04-10 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (2.409 Å) | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus. Nat Microbiol, 4, 2019
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6IEA
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![BU of 6iea by Molmil](/molmil-images/mine/6iea) | Structure of RVFV Gn and human monoclonal antibody R13 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NSmGnGc, ... | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | Deposit date: | 2018-09-13 | Release date: | 2019-04-10 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus. Nat Microbiol, 4, 2019
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6IEK
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![BU of 6iek by Molmil](/molmil-images/mine/6iek) | Structure of RVFV Gn and human monoclonal antibody R12 | Descriptor: | Heavy chain of Fab R12, Light chain of Fab R12, NSmGnGc | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | Deposit date: | 2018-09-14 | Release date: | 2019-04-10 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus. Nat Microbiol, 4, 2019
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6IEC
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![BU of 6iec by Molmil](/molmil-images/mine/6iec) | Structure of RVFV Gn and human monoclonal antibody R17 | Descriptor: | NSmGnGc, R17 H chain, R17 L chain | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | Deposit date: | 2018-09-13 | Release date: | 2019-04-10 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus. Nat Microbiol, 4, 2019
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6L69
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![BU of 6l69 by Molmil](/molmil-images/mine/6l69) | Crystal structure of CYP154C2 from Streptomyces avermitilis | Descriptor: | Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Xu, L.H, Fushinobu, S. | Deposit date: | 2019-10-28 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Regio- and stereoselective hydroxylation of testosterone by a novel cytochrome P450 154C2 from Streptomyces avermitilis. Biochem.Biophys.Res.Commun., 522, 2020
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7VH0
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![BU of 7vh0 by Molmil](/molmil-images/mine/7vh0) | MT2-remalteon-Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, Melatonin receptor type 1B, ... | Authors: | Wang, Q.G, Lu, Q.Y. | Deposit date: | 2021-09-20 | Release date: | 2022-03-02 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
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7VGY
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![BU of 7vgy by Molmil](/molmil-images/mine/7vgy) | Melatonin receptor1-2-Iodomelatonin-Gicomplex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, Q.G, Lu, Q.Y. | Deposit date: | 2021-09-20 | Release date: | 2022-03-02 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
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7VGZ
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![BU of 7vgz by Molmil](/molmil-images/mine/7vgz) | MT1-remalteon-Gi complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, Q.G, Lu, Q.Y. | Deposit date: | 2021-09-20 | Release date: | 2022-03-02 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
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7VY5
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![BU of 7vy5 by Molmil](/molmil-images/mine/7vy5) | Coxsackievirus B3 (VP3-234Q) incubation with CD55 at pH7.4 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-13 | Release date: | 2022-01-19 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VXZ
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![BU of 7vxz by Molmil](/molmil-images/mine/7vxz) | |
7VYL
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![BU of 7vyl by Molmil](/molmil-images/mine/7vyl) | |
7VYK
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7VXH
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![BU of 7vxh by Molmil](/molmil-images/mine/7vxh) | Coxsackievirus B3 full particle at pH7.4 (VP3-234Q) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-12 | Release date: | 2022-01-19 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VYM
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7VY0
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![BU of 7vy0 by Molmil](/molmil-images/mine/7vy0) | Coxsackievirus B3 full particle at pH7.4 (VP3-234N) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-13 | Release date: | 2022-01-19 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VY6
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![BU of 7vy6 by Molmil](/molmil-images/mine/7vy6) | Coxsackievirus B3(VP3-234N) incubate with CD55 at pH7.4 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-13 | Release date: | 2022-01-19 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7W14
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![BU of 7w14 by Molmil](/molmil-images/mine/7w14) | |
7W17
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![BU of 7w17 by Molmil](/molmil-images/mine/7w17) | Coxsackievirus B3 full particle at pH7.4 (VP3-234E) | Descriptor: | PALMITIC ACID, VP1, VP2, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-19 | Release date: | 2022-01-19 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YTJ
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![BU of 7ytj by Molmil](/molmil-images/mine/7ytj) | Cryo-EM structure of VTC complex | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, INOSITOL HEXAKISPHOSPHATE, PHOSPHATE ION, ... | Authors: | Guan, Z.Y, Chen, J, Liu, R.W, Chen, Y.K, Xing, Q, Du, Z.M, Liu, Z. | Deposit date: | 2022-08-15 | Release date: | 2023-02-22 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex. Nat Commun, 14, 2023
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6K0B
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![BU of 6k0b by Molmil](/molmil-images/mine/6k0b) | cryo-EM structure of archaeal Ribonuclease P with mature tRNA | Descriptor: | 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ... | Authors: | Wan, F, Lan, P, Wu, J, Lei, M. | Deposit date: | 2019-05-05 | Release date: | 2019-06-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme. Nat Commun, 10, 2019
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6K0A
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![BU of 6k0a by Molmil](/molmil-images/mine/6k0a) | cryo-EM structure of an archaeal Ribonuclease P | Descriptor: | 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ... | Authors: | Wan, F, Lan, P, Wu, J, Lei, M. | Deposit date: | 2019-05-05 | Release date: | 2019-06-19 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme. Nat Commun, 10, 2019
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3TJC
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![BU of 3tjc by Molmil](/molmil-images/mine/3tjc) | Co-crystal structure of jak2 with thienopyridine 8 | Descriptor: | 4-amino-N-methyl-2-[4-(morpholin-4-yl)phenyl]thieno[3,2-c]pyridine-7-carboxamide, Tyrosine-protein kinase JAK2 | Authors: | Huang, X. | Deposit date: | 2011-08-24 | Release date: | 2011-11-30 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of potent and highly selective thienopyridine janus kinase 2 inhibitors. J.Med.Chem., 54, 2011
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3TJD
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![BU of 3tjd by Molmil](/molmil-images/mine/3tjd) | co-crystal structure of Jak2 with thienopyridine 19 | Descriptor: | 4-amino-2-[4-(tert-butylsulfamoyl)phenyl]-N-methylthieno[3,2-c]pyridine-7-carboxamide, Tyrosine-protein kinase JAK2 | Authors: | Huang, X. | Deposit date: | 2011-08-24 | Release date: | 2011-11-30 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Discovery of potent and highly selective thienopyridine janus kinase 2 inhibitors. J.Med.Chem., 54, 2011
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4WSI
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![BU of 4wsi by Molmil](/molmil-images/mine/4wsi) | Crystal Structure of PALS1/Crb complex | Descriptor: | MAGUK p55 subfamily member 5, Protein crumbs | Authors: | Wei, Z, Li, Y, Zhang, M. | Deposit date: | 2014-10-28 | Release date: | 2014-11-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex. Proc.Natl.Acad.Sci.USA, 111, 2014
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