8UM3
 
 | | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z203039992 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 6-chlorotetrazolo[1,5-b]pyridazine, ... | | Authors: | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | | Deposit date: | 2023-10-17 | | Release date: | 2023-11-01 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.925 Å) | | Cite: | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z203039992
To Be Published
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5A0E
 | | Crystal structure of cyclophilin D in complex with CsA analogue, JW47. | | Descriptor: | JW47, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL | | Authors: | Warne, J, Pryce, G, Hill, J, Shi, X, Lenneras, F, Puentes, F, Kip, M, Hilditch, L, Walker, P, Simone, M, Chan, A.W.E, Towers, G, Coker, A.R, Duchen, M, Szabadkai, G, Baker, D, Selwood, D.L. | | Deposit date: | 2015-04-19 | | Release date: | 2015-12-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects Against Neuro-Degeneration in Experimental Multiple Sclerosis.
J.Biol.Chem., 291, 2016
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9FQR
 | | 96-nm repeat of axonemal doublet microtubules from bovine sperm | | Descriptor: | A-kinase anchoring protein 14, ATP6V1F neighbor, Actin, ... | | Authors: | Leung, M.R, Sun, C, Zeng, J, Anderson, J.R, Niu, Q, Huang, W, Noteborn, W.E.M, Brown, A, Zeev-Ben-Mordehai, T, Zhang, R. | | Deposit date: | 2024-06-21 | | Release date: | 2025-03-26 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Structural diversity of axonemes across mammalian motile cilia.
Nature, 637, 2025
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8V7R
 | | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z56772132 | | Descriptor: | (5R)-5-[2-(4-methoxyphenyl)ethyl]-5-methylimidazolidine-2,4-dione, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | | Authors: | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | | Deposit date: | 2023-12-04 | | Release date: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z56772132
To Be Published
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8V7U
 | | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z729726784 | | Descriptor: | 1,2-ETHANEDIOL, 2-cyclopentyl-N-(3-methyl-1,2,4-oxadiazol-5-yl)acetamide, DIMETHYL SULFOXIDE, ... | | Authors: | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | | Deposit date: | 2023-12-04 | | Release date: | 2023-12-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z729726784
To Be Published
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8CPM
 | | Human apoferritin after 405 nm laser exposure | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.81 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPX
 | | Human apoferritin after 488 nm laser exposure in presence of rsEGFP2 | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.76 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPV
 | | Human apoferritin | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.76 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPS
 | | Human apoferritin | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.82 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPW
 | | Human apoferritin after 405 nm + 488 nm laser exposure in presence of rsEGFP2 | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.79 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPU
 | | Human apoferritin after 561 nm laser exposure | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.76 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPT
 | | Human apoferritin after 488 nm laser exposure | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.79 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8PN6
 | | Crystal Structure of co-expressed NS2B-NS3 Protease from Zika Virus | | Descriptor: | Genome polyprotein, Serine protease subunit NS2B | | Authors: | Ni, X, Fairhead, M, Balcomb, B.H, Aschenbrenner, J.C, Ferreira, L.M, Godoy, A.S, Lithgo, R.M, MacLean, E.M, Marples, P.G, Thompson, W, Tomlinson, C.W.E, Szommer, T, Wild, C, Wright, N.D, Koekemoer, L, Fearon, D, Walsh, M.A, von Delft, F. | | Deposit date: | 2023-06-29 | | Release date: | 2023-08-16 | | Last modified: | 2024-08-14 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Crystal Structure of co-expressed NS2B-NS3 Protease from Zika Virus
To Be Published
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8R5J
 | | Crystal structure of MERS-CoV main protease | | Descriptor: | Non-structural protein 11 | | Authors: | Balcomb, B.H, Fairhead, M, Koekemoer, L, Lithgo, R.M, Aschenbrenner, J.C, Chandran, A.V, Godoy, A.S, Lukacik, P, Marples, P.G, Mazzorana, M, Ni, X, Strain-Damerell, C, Thompson, W, Tomlinson, C.W.E, Wild, C, Winokan, M, Fearon, D, Walsh, M.A, von Delft, F. | | Deposit date: | 2023-11-16 | | Release date: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.898 Å) | | Cite: | Crystal structure of MERS-CoV main protease
To Be Published
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8POA
 | | Structure of Coxsackievirus A16 (G-10) 2A protease | | Descriptor: | GLYCEROL, Protease 2A, ZINC ION | | Authors: | Lithgo, R.M, Fairhead, M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Godoy, A.S, Marples, P.G, Ni, X, Tomlinson, C.W.E, Thompson, W, Wild, C, Fearon, D, Walsh, M.A, von Delft, F. | | Deposit date: | 2023-07-04 | | Release date: | 2023-08-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals.
Biorxiv, 2024
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7A9Z
 | | Structural comparison of cellular retinoic acid binding protein I and II in the presence and absence of natural and synthetic ligands | | Descriptor: | 4-[2-(5,5,8,8-tetramethyl-6,7-dihydroquinoxalin-2-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 1 | | Authors: | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | | Deposit date: | 2020-09-02 | | Release date: | 2021-02-17 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands.
Acta Crystallogr D Struct Biol, 77, 2021
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7NGJ
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7NGD
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7AA1
 | | Structural comparison of cellular retinoic acid binding proteins I and II in the presence and absence of natural and synthetic ligands | | Descriptor: | 4-[2-(5,5,8,8-tetramethyl-6,7-dihydroquinoxalin-2-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2 | | Authors: | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | | Deposit date: | 2020-09-02 | | Release date: | 2021-02-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands.
Acta Crystallogr D Struct Biol, 77, 2021
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7NGS
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7NGX
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7NGO
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7NGK
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7NGT
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7NGU
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