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7NCH
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BU of 7nch by Molmil
Type 1B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCK
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BU of 7nck by Molmil
Type 3 alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 5
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCA
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BU of 7nca by Molmil
Type 1A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
8BQU
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BU of 8bqu by Molmil
Molecular basis of ZP3/ZP1 heteropolymerization: crystal structure of a native vertebrate egg coat filament
Descriptor: Choriogenin H, Zona pellucida sperm-binding protein 3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Bokhove, M, de Sanctis, D, Yasumasu, S, Jovine, L.
Deposit date:2022-11-21
Release date:2024-03-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat.
Cell, 187, 2024
1UKX
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BU of 1ukx by Molmil
Solution structure of the RWD domain of mouse GCN2
Descriptor: GCN2 eIF2alpha kinase
Authors:Nameki, N, Yoneyama, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-09-03
Release date:2004-08-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the RWD domain of the mouse GCN2 protein.
Protein Sci., 13, 2004
7Y4A
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BU of 7y4a by Molmil
Crystal structure of human ELMO1 RBD-RhoG complex
Descriptor: Engulfment and cell motility protein 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Tsuda, K, Kukimoto-Niino, M, Shirouzu, M.
Deposit date:2022-06-14
Release date:2023-03-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Targeting Ras-binding domain of ELMO1 by computational nanobody design.
Commun Biol, 6, 2023
1UA7
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BU of 1ua7 by Molmil
Crystal Structure Analysis of Alpha-Amylase from Bacillus Subtilis complexed with Acarbose
Descriptor: 4,6-dideoxy-alpha-D-xylo-hexopyranose-(1-4)-alpha-D-glucopyranose, 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, Alpha-amylase, ...
Authors:Kagawa, M, Fujimoto, Z, Momma, M, Takase, K, Mizuno, H.
Deposit date:2003-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of Bacillus subtilis alpha-amylase in complex with acarbose
J.BACTERIOL., 185, 2003
1GOB
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BU of 1gob by Molmil
COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION
Descriptor: RIBONUCLEASE H
Authors:Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S.
Deposit date:1993-05-10
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
1GOC
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BU of 1goc by Molmil
COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION
Descriptor: RIBONUCLEASE H
Authors:Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S.
Deposit date:1993-05-10
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
1GOA
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BU of 1goa by Molmil
COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION
Descriptor: RIBONUCLEASE H
Authors:Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S.
Deposit date:1993-05-10
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
7Y6L
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BU of 7y6l by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab816
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab816 heavy chain, Ab816 light chain, ...
Authors:Uchikubo, T, Shirouzu, M.
Deposit date:2022-06-21
Release date:2023-06-21
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
7Y6N
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BU of 7y6n by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab803
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab803 heavy chain, Ab803 light chain, ...
Authors:Uchikubo, T, Shirouzu, M.
Deposit date:2022-06-21
Release date:2023-06-21
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
1N27
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BU of 1n27 by Molmil
Solution structure of the PWWP domain of mouse Hepatoma-derived growth factor, related protein 3
Descriptor: Hepatoma-derived growth factor, related protein 3
Authors:Nameki, N, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-10-22
Release date:2003-12-23
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the PWWP domain of the hepatoma-derived growth factor family.
Protein Sci., 14, 2005
6OQ5
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BU of 6oq5 by Molmil
Structure of the full-length Clostridium difficile toxin B in complex with 3 VHHs
Descriptor: 5D, 7F, E3, ...
Authors:Chen, P, Lam, K, Jin, R.
Deposit date:2019-04-25
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.87 Å)
Cite:Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
6OQ6
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BU of 6oq6 by Molmil
Structure of the pore forming fragment of Clostridium difficile toxin B in complex with VHH 5D
Descriptor: 5D, Toxin B
Authors:Chen, P, Lam, K, Jin, R.
Deposit date:2019-04-25
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
6OQ8
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BU of 6oq8 by Molmil
Structure of the GTD domain of Clostridium difficile toxin B in complex with VHH 7F
Descriptor: 7F, Toxin B
Authors:Chen, P, Lam, K, Jin, R.
Deposit date:2019-04-25
Release date:2019-07-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
6OQ7
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BU of 6oq7 by Molmil
Structure of the GTD domain of Clostridium difficile toxin B in complex with VHH E3
Descriptor: E3, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Chen, P, Lam, K, Jin, R.
Deposit date:2019-04-25
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
5JGD
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BU of 5jgd by Molmil
Crystal structure of human TAK1/TAB1 fusion protein in complex with ligand 12
Descriptor: N-(2-isopropoxy-3-(4-methylpiperazine-1-carbonyl)phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide, TAK1 kinase - TAB1 chimera fusion protein
Authors:Irie, M, Nakamura, M, Fukami, T.A, Matsuura, T, Morishima, K.
Deposit date:2016-04-20
Release date:2016-07-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Discovery of a potent and highly selective transforming growth factor beta receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD)
Bioorg.Med.Chem., 24, 2016
4Y59
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BU of 4y59 by Molmil
Crystal structure of ALiS1-Streptavidin complex
Descriptor: 2-[3-(trifluoromethyl)phenyl]furo[3,2-c]pyridin-4(5H)-one, Streptavidin
Authors:Sugiyama, S, Terai, T, Kohno, M, Ishida, H, Nagano, T.
Deposit date:2015-02-11
Release date:2015-09-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport
J.Am.Chem.Soc., 137, 2015
5JGA
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BU of 5jga by Molmil
Crystal structure of human TAK1/TAB1 fusion protein in complex with ligand 11c
Descriptor: N-[5-(4-methylpiperazine-1-carbonyl)[1,1'-biphenyl]-2-yl]-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide, TAK1 kinase - TAB1 chimera fusion protein
Authors:Irie, M, Nakamura, M, Fukami, T.A, Matsuura, T, Morishima, K.
Deposit date:2016-04-19
Release date:2016-07-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of a potent and highly selective transforming growth factor beta receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD)
Bioorg.Med.Chem., 24, 2016
4Y5D
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BU of 4y5d by Molmil
CRYSTAL STRUCTURE OF ALiS2-STREPTAVIDIN COMPLEX
Descriptor: 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, DIMETHYL SULFOXIDE, HEXAETHYLENE GLYCOL, ...
Authors:Sugiyama, S, Terai, T, Kohno, M, Ishida, H, Nagano, T.
Deposit date:2015-02-11
Release date:2015-09-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport
J.Am.Chem.Soc., 137, 2015
5JGB
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BU of 5jgb by Molmil
Crystal structure of human TAK1/TAB1 fusion protein in complex with ligand 10
Descriptor: N-(2-methoxy-4-{[3-(4-methylpiperazin-1-yl)propyl]carbamoyl}phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide, TAK1 kinase - TAB1 chimera fusion protein
Authors:Irie, M, Nakamura, M, Fukami, T.A, Matsuura, T, Morishima, K.
Deposit date:2016-04-20
Release date:2016-07-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of a potent and highly selective transforming growth factor beta receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD)
Bioorg.Med.Chem., 24, 2016
2RPP
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BU of 2rpp by Molmil
Solution structure of Tandem zinc finger domain 12 in Muscleblind-like protein 2
Descriptor: Muscleblind-like protein 2, ZINC ION
Authors:Abe, C, Dang, W, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-06-24
Release date:2009-05-12
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the RNA binding domain in the human muscleblind-like protein 2
Protein Sci., 18, 2009
2RR4
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BU of 2rr4 by Molmil
Complex structure of the zf-CW domain and the H3K4me3 peptide
Descriptor: Histone H3, ZINC ION, Zinc finger CW-type PWWP domain protein 1
Authors:He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2010-03-24
Release date:2010-09-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insight into the zinc finger CW domain as a histone modification reader
Structure, 18, 2010
7VBM
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BU of 7vbm by Molmil
The mouse nucleosome structure containing H3mm18 aided by PL2-6 scFv
Descriptor: DNA (126-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
Authors:Hirai, S, Takizawa, Y, Kujirai, T, Kurumizaka, H.
Deposit date:2021-08-31
Release date:2022-01-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant.
Nucleic Acids Res., 50, 2022

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