8H69
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![BU of 8h69 by Molmil](/molmil-images/mine/8h69) | Cryo-EM structure of influenza RNA polymerase | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3'), ... | Authors: | Li, H, Wu, Y, Liang, H, Liu, Y. | Deposit date: | 2022-10-16 | Release date: | 2023-06-28 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles. Nat.Struct.Mol.Biol., 30, 2023
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8CPE
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3BYU
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![BU of 3byu by Molmil](/molmil-images/mine/3byu) | co-crystal structure of Lck and aminopyrimidine reverse amide 23 | Descriptor: | 2-methyl-N-{4-methyl-3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)carbamoyl]phenyl}-3-(trifluoromethyl)benzamide, Proto-oncogene tyrosine-protein kinase LCK | Authors: | Huang, X. | Deposit date: | 2008-01-16 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation. J.Med.Chem., 51, 2008
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5VX1
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![BU of 5vx1 by Molmil](/molmil-images/mine/5vx1) | Bak L100A | Descriptor: | Bcl-2 homologous antagonist/killer | Authors: | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | Deposit date: | 2017-05-23 | Release date: | 2017-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.224 Å) | Cite: | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWZ
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![BU of 5vwz by Molmil](/molmil-images/mine/5vwz) | Bak in complex with Bim-h3Pc | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, AMMONIUM ION, Bcl-2 homologous antagonist/killer, ... | Authors: | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | Deposit date: | 2017-05-23 | Release date: | 2017-11-15 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (1.622 Å) | Cite: | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWY
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5VX3
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![BU of 5vx3 by Molmil](/molmil-images/mine/5vx3) | Bcl-xL in complex with Bim-h3Pc-RT | Descriptor: | 1,2-ETHANEDIOL, Bcl-2-like protein 1, Bcl-2-like protein 11 | Authors: | Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. | Deposit date: | 2017-05-23 | Release date: | 2017-11-15 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (1.945 Å) | Cite: | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWV
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![BU of 5vwv by Molmil](/molmil-images/mine/5vwv) | Bak core latch dimer in complex with Bim-BH3 - Cubic | Descriptor: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11, ... | Authors: | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | Deposit date: | 2017-05-23 | Release date: | 2017-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.897 Å) | Cite: | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VX2
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![BU of 5vx2 by Molmil](/molmil-images/mine/5vx2) | Mcl-1 in complex with Bim-h3Pc-RT | Descriptor: | 1,2-ETHANEDIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1 chimera | Authors: | Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. | Deposit date: | 2017-05-23 | Release date: | 2017-11-15 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (1.851 Å) | Cite: | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWW
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![BU of 5vww by Molmil](/molmil-images/mine/5vww) | Bak core latch dimer in complex with Bim-RT - Tetragonal | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BROMIDE ION, Bcl-2 homologous antagonist/killer, ... | Authors: | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | Deposit date: | 2017-05-23 | Release date: | 2017-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5WWN
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![BU of 5wwn by Molmil](/molmil-images/mine/5wwn) | Crystal structure of Tsr1 | Descriptor: | Ribosome biogenesis protein TSR1, SULFATE ION | Authors: | Ye, K, Wang, B. | Deposit date: | 2017-01-03 | Release date: | 2017-06-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
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5WXM
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![BU of 5wxm by Molmil](/molmil-images/mine/5wxm) | Crystal structure of the Imp3 and Mpp10 complex | Descriptor: | SULFATE ION, U3 small nucleolar RNA-associated protein MPP10, U3 small nucleolar ribonucleoprotein protein IMP3 | Authors: | Ye, K, Zheng, S. | Deposit date: | 2017-01-07 | Release date: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
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5WWO
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![BU of 5wwo by Molmil](/molmil-images/mine/5wwo) | Crystal structure of Enp1 | Descriptor: | Essential nuclear protein 1, Protein LTV1 | Authors: | Ye, K, Zhang, W. | Deposit date: | 2017-01-03 | Release date: | 2017-06-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
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5WYJ
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![BU of 5wyj by Molmil](/molmil-images/mine/5wyj) | Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... | Authors: | Ye, K, Zhu, X, Sun, Q. | Deposit date: | 2017-01-13 | Release date: | 2017-03-29 | Last modified: | 2019-10-09 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome. Elife, 6, 2017
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5WWM
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![BU of 5wwm by Molmil](/molmil-images/mine/5wwm) | Crystal structure of the TPR domain of Rrp5 | Descriptor: | SULFATE ION, rRNA biogenesis protein RRP5 | Authors: | Ye, K, Chen, X. | Deposit date: | 2017-01-03 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.809 Å) | Cite: | Correction: Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
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5WYL
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5WYK
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![BU of 5wyk by Molmil](/molmil-images/mine/5wyk) | Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... | Authors: | Ye, K, Zhu, X, Sun, Q. | Deposit date: | 2017-01-13 | Release date: | 2017-03-29 | Last modified: | 2017-05-17 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome. Elife, 6, 2017
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5WY3
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5WXL
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![BU of 5wxl by Molmil](/molmil-images/mine/5wxl) | Crystal structure of the Rrs1 and Rpf2 complex | Descriptor: | Regulator of ribosome biosynthesis, Ribosome biogenesis protein RPF2 | Authors: | Ye, K, Zheng, S. | Deposit date: | 2017-01-07 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular architecture of the 90S small subunit pre-ribosome Elife, 6, 2017
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7AXK
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![BU of 7axk by Molmil](/molmil-images/mine/7axk) | Crystal structure of the hPXR-LBD in complex with estradiol and endosulfan | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ESTRADIOL, GLYCEROL, ... | Authors: | Huet, T, Delfosse, V, Bourguet, W. | Deposit date: | 2020-11-09 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AXI
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![BU of 7axi by Molmil](/molmil-images/mine/7axi) | Crystal structure of the hPXR-LBD in complex with estradiol and cis-chlordane | Descriptor: | (+)cis-chlordane, (-)cis-chlordane, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | Authors: | Huet, T, Delfosse, V, Bourguet, W. | Deposit date: | 2020-11-09 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AXF
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1ZY3
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![BU of 1zy3 by Molmil](/molmil-images/mine/1zy3) | |
4QMF
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![BU of 4qmf by Molmil](/molmil-images/mine/4qmf) | Structure of the Krr1 and Faf1 complex from Saccharomyces cerevisiae | Descriptor: | KRR1 small subunit processome component, Protein FAF1 | Authors: | Zheng, S, Ye, K. | Deposit date: | 2014-06-16 | Release date: | 2014-07-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Interaction between ribosome assembly factors Krr1 and Faf1 is essential for formation of small ribosomal subunit in yeast J.Biol.Chem., 289, 2014
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7AL2
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![BU of 7al2 by Molmil](/molmil-images/mine/7al2) | |