3ZN1
| LSD1-CoREST in complex with PRLYLV peptide | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ... | Authors: | Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A. | Deposit date: | 2013-02-13 | Release date: | 2013-06-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase. Acs Chem.Biol., 8, 2013
|
|
4B64
| A. fumigatus ornithine hydroxylase (SidA) bound to NADP and Lysine | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ... | Authors: | Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A. | Deposit date: | 2012-08-09 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases. Biochemistry, 51, 2012
|
|
4BBY
| MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE | Descriptor: | ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A. | Deposit date: | 2012-09-28 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4BJY
| Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Platinum derivative | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, ... | Authors: | Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. | Deposit date: | 2013-04-21 | Release date: | 2013-07-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
|
|
2YG6
| Structure-based redesign of cofactor binding in Putrescine Oxidase: P15I-A394C double mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PUTRESCINE OXIDASE, ... | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-based redesign of cofactor binding in putrescine oxidase. Biochemistry, 50, 2011
|
|
2YG7
| Structure-based redesign of cofactor binding in Putrescine Oxidase: A394C-A396T-Q431G Triple mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PUTRESCINE OXIDASE | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase. Biochemistry, 50, 2011
|
|
4AP3
| Oxidized steroid monooxygenase bound to NADP | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, STEROID MONOOXYGENASE, ... | Authors: | Franceschini, S, van Beek, H.L, Martinoli, C, Pennetta, A, Fraaije, M.W, Mattevi, A. | Deposit date: | 2012-03-30 | Release date: | 2012-05-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Exploring the Structural Basis of Substrate Preferences in Baeyer-Villiger Monooxygenases: Insight from Steroid Monooxygenase. J.Biol.Chem., 287, 2012
|
|
2YG3
| Structure-based redesign of cofactor binding in Putrescine Oxidase: wild type enzyme | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PUTRESCINE OXIDASE, ... | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase. Biochemistry, 50, 2011
|
|
4BCA
| MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Tyr578Phe mutant | Descriptor: | ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, CHLORIDE ION, ... | Authors: | Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A. | Deposit date: | 2012-10-01 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
2XLS
| Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: Asn78Lys mutant | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Orru, R, Fraaije, M.W, Mattevi, A. | Deposit date: | 2010-07-21 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Joint-Functions of Protein Residues and Nadp(H) in Oxygen-Activation by Flavin-Containing Monooxygenase J.Biol.Chem., 285, 2010
|
|
1DZN
| Asp170Ser mutant of vanillyl-alcohol oxidase | Descriptor: | 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol, FLAVIN-ADENINE DINUCLEOTIDE, VANILLYL-ALCOHOL OXIDASE | Authors: | Van Den heuvel, R.H.H, Fraaije, M.W, Van Berkel, W.J.H, Mattevi, A. | Deposit date: | 2000-03-05 | Release date: | 2000-03-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Asp170 is Crucial for the Redox Properties of Vanillyl-Alcohol Oxidase J.Biol.Chem., 275, 2000
|
|
1E0Y
| Structure of the D170S/T457E double mutant of vanillyl-alcohol oxidase | Descriptor: | ALPHA,ALPHA,ALPHA-TRIFLUORO-P-CRESOL, FLAVIN-ADENINE DINUCLEOTIDE, VANILLYL-ALCOHOL OXIDASE | Authors: | Van Der heuvel, R.H.H, Van Berkel, W.J.H, Mattevi, A. | Deposit date: | 2000-04-11 | Release date: | 2000-04-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Inversion of Stereospecificity in Vanillyl-Alcohol Oxidase Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
2Y48
| Crystal structure of LSD1-CoREST in complex with a N-terminal SNAIL peptide | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC DEMETHYLASE 1A, REST COREPRESSOR 1, ... | Authors: | Baron, R, Binda, C, Tortorici, M, McCammon, J.A, Mattevi, A. | Deposit date: | 2011-01-05 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase Lsd1-Corest Complex. Structure, 19, 2011
|
|
2XLP
| Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: Asn78Ser mutant | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Orru, R, Fraaije, M.W, Mattevi, A. | Deposit date: | 2010-07-21 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Joint functions of protein residues and NADP(H) in oxygen activation by flavin-containing monooxygenase. J. Biol. Chem., 285, 2010
|
|
2XLT
| Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: complex with 3-Acetylpyridine adenine dinucleotide phosphate (APADP) | Descriptor: | 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Orru, R, Fraaije, M.W, Mattevi, A. | Deposit date: | 2010-07-21 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Joint functions of protein residues and NADP(H) in oxygen activation by flavin-containing monooxygenase. J. Biol. Chem., 285, 2010
|
|
1E8G
| |
2XLR
| |
2XLU
| Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: complex with thioNADP | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Orru, R, Fraaije, M.W, Mattevi, A. | Deposit date: | 2010-07-21 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Joint-Functions of Protein Residues and Nadp(H) in Oxygen-Activation by Flavin-Containing Monooxygenase J.Biol.Chem., 285, 2010
|
|
2YG4
| Structure-based redesign of cofactor binding in Putrescine Oxidase: wild type bound to Putrescine | Descriptor: | 4-HYDROXYBUTAN-1-AMINIUM, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase. Biochemistry, 50, 2011
|
|
2YG5
| Structure-based redesign of cofactor binding in Putrescine Oxidase: A394C mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PUTRESCINE OXIDASE, ... | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase. Biochemistry, 50, 2011
|
|
4AP1
| Oxidized steroid monooxygenase bound to NADP | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, STEROID MONOOXYGENASE, ... | Authors: | Franceschini, S, van Beek, H.L, Martinoli, C, Pennetta, A, Fraaije, M.W, Mattevi, A. | Deposit date: | 2012-03-30 | Release date: | 2012-05-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Exploring the Structural Basis of Substrate Preferences in Baeyer-Villiger Monooxygenases: Insight from Steroid Monooxygenase. J.Biol.Chem., 287, 2012
|
|
4CRT
| Crystal structure of human monoamine oxidase B in complex with the multi-target inhibitor ASS234 | Descriptor: | (E)-N-methyl-N-[[1-methyl-5-[3-[1-(phenylmethyl)piperidin-4-yl]propoxy]indol-2-yl]methyl]prop-1-en-1-amine, AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Esteban, G, Allan, J, Samadi, A, Mattevi, A, Unzeta, M, Marco-Contelles, J, Binda, C, Ramsay, R.R. | Deposit date: | 2014-02-28 | Release date: | 2014-04-02 | Last modified: | 2014-05-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Kinetic and Structural Analysis of the Irreversible Inhibition of Human Monoamine Oxidases by Ass234, a Multi-Target Compound Designed for Use in Alzheimer'S Disease. Biochim.Biophys.Acta, 1844, 2014
|
|
4BJZ
| Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Native data | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, ... | Authors: | Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. | Deposit date: | 2013-04-21 | Release date: | 2013-07-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
|
|
4BK1
| Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: H213S mutant in complex with 3-hydroxybenzoate | Descriptor: | 3-HYDROXYBENZOIC ACID, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. | Deposit date: | 2013-04-21 | Release date: | 2013-07-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
|
|
4BK2
| Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Q301E mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, PROBABLE SALICYLATE MONOOXYGENASE | Authors: | Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. | Deposit date: | 2013-04-21 | Release date: | 2013-07-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
|
|