7D5Z
 
 | | Crystal structure of EBV gH/gL bound with neutralizing antibody 1D8 | | 分子名称: | Envelope glycoprotein H, Envelope glycoprotein L, heavy chain of 1D8, ... | | 著者 | Zhu, Q, Shan, S, Yu, J, Wang, X, Zhang, L, Zeng, M. | | 登録日 | 2020-09-28 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | A Neutralizing Antibody Targeting a New Site of Vulnerability on Epstein-Barr Virus gH/gL Protects against Dual-Tropic Infection
To Be Published
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8Y4C
 | | BA.2.86 S-trimer in complex with Nab XGv280 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, XGv280 Heavy chain, ... | | 著者 | Zhu, Q, Liu, P. | | 登録日 | 2024-01-30 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Enhancing RBD exposure and S1 shedding by an extremely conserved SARS-CoV-2 NTD epitope.
Signal Transduct Target Ther, 9, 2024
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8Y4A
 | | BA.2.86 S-trimer in complex with Nab XG2v046 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Zhu, Q, Liu, P. | | 登録日 | 2024-01-30 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Enhancing RBD exposure and S1 shedding by an extremely conserved SARS-CoV-2 NTD epitope.
Signal Transduct Target Ther, 9, 2024
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2JTB
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7BYR
 | | BD23-Fab in complex with the S ectodomain trimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab23-Fab-Heavy Chain, ... | | 著者 | Zhu, Q, Wang, G, Xiao, J. | | 登録日 | 2020-04-24 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells.
Cell, 182, 2020
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5WRR
 | | Crystal structure of Fam20A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pseudokinase FAM20A | | 著者 | Zhu, Q. | | 登録日 | 2016-12-03 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | | 主引用文献 | Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding
Elife, 6, 2017
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5WRS
 | | Crystal Structure of Fam20A in complex with ATP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhu, Q. | | 登録日 | 2016-12-03 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding
Elife, 6, 2017
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5YH3
 | | The structure of hFam20C and hFam20A complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Extracellular serine/threonine protein kinase FAM20C, Pseudokinase FAM20A | | 著者 | Zhu, Q, Xiao, J. | | 登録日 | 2017-09-27 | | 公開日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
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2DHS
 | | Solution Structure of Nucleic Acid Binding Protein CUGBP1ab and its Binding Study with DNA and RNA | | 分子名称: | CUG triplet repeat RNA-binding protein 1 | | 著者 | Xia, Y.L, Jun, K.Y, Zhu, Q, Han, X.G, Zhang, H, Timchenko, L, Swanson, M, Gao, X.L. | | 登録日 | 2006-03-25 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Nucleic Acid Binding Protein CUGBP1ab and its Binding Study with DNA and RNA
To be Published
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1SOC
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7YK6
 | | Cryo-EM structure of the compound 4-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | | 分子名称: | 1-[2-(4-chlorophenyl)ethyl]-3-[(7-ethyl-5-oxidanyl-1H-indol-3-yl)methylideneamino]guanidine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Liu, H, Xu, H.E, Yang, D.H, Wang, M.W. | | 登録日 | 2022-07-21 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
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7YK7
 | | Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Xu, H.E, Yang, D.H, Liu, H, Wang, M.W. | | 登録日 | 2022-07-21 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
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7YJ4
 | | Cryo-EM structure of the INSL5-bound human relaxin family peptidereceptor 4 (RXFP4)-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Liu, H, Xu, H.E, Yang, D.H, Wang, M.W. | | 登録日 | 2022-07-19 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
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7CHF
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7CHH
 | | Cryo-EM structure of the SARS-CoV-2 S-6P in complex with BD-368-2 Fabs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BD-368-2 Fab heavy chain, ... | | 著者 | Xiao, J, Zhu, Q, Wang, G. | | 登録日 | 2020-07-05 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
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7CHE
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7CHB
 | | Crystal structure of the SARS-CoV-2 RBD in complex with BD-236 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BD-236 Fab heavy chain, BD-236 Fab light chain, ... | | 著者 | Xiao, J, Zhu, Q. | | 登録日 | 2020-07-05 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
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2SOC
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5VRT
 | | Nonheme Iron Replacement in a Biosynthetic Nitric Oxide Reductase Model Performing O2 Reduction to Water: Co-bound FeBMb | | 分子名称: | COBALT (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Reed, J, Shi, Y, Zhu, Q, Chakraborty, S, Mirs, E.N, Petrik, I.D, Bhagi-Damodaran, A, Ross, M, Moenne-Loccoz, P, Zhang, Y, Lu, Y. | | 登録日 | 2017-05-11 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | | 主引用文献 | Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism.
J. Am. Chem. Soc., 139, 2017
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5VNU
 | | Nonheme Iron Replacement in a Biosynthetic Nitric Oxide Reductase Model Performing O2 Reduction to Water: Mn-bound FeBMb | | 分子名称: | MANGANESE (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Reed, J, Shi, Y, Zhu, Q, Chakraborty, S, Mirs, E.N, Petrik, I.D, Bhagi-Damodaran, A, Ross, M, Moenne-Loccoz, P, Zhang, Y, Lu, Y. | | 登録日 | 2017-05-01 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.584 Å) | | 主引用文献 | Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism.
J. Am. Chem. Soc., 139, 2017
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5GZA
 | | protein O-mannose kinase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose, 4-METHYL-2H-CHROMEN-2-ONE, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Xiao, J. | | 登録日 | 2016-09-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of protein O-mannose kinase reveals a unique active site architecture
Elife, 5, 2016
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7WQ5
 | | Crystal structure of Arabidopsis transcriptional factor WRINKLED1 with dsDNA | | 分子名称: | AMMONIUM ION, DNA (5'-D(P*GP*TP*GP*GP*AP*CP*GP*AP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*GP*AP*AP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*TP*TP*CP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*TP*CP*GP*TP*CP*CP*AP*C)-3'), ... | | 著者 | Zhu, Q, Gao, Y.G. | | 登録日 | 2022-01-24 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Molecular basis of the key regulator WRINKLED1 in plant oil biosynthesis.
Sci Adv, 8, 2022
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5UDD
 | | Crystal Structure of RSV F B9320 Bound to MEDI8897 | | 分子名称: | Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, MEDI8897 Fab Light Chain, ... | | 著者 | McLellan, J.S. | | 登録日 | 2016-12-26 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
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5UDE
 | | Crystal Structure of RSV F B9320 DS-Cav1 | | 分子名称: | Fusion glycoprotein F0, SULFATE ION | | 著者 | McLellan, J.S. | | 登録日 | 2016-12-26 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
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5UDC
 | | Crystal Structure of RSV F A2 Bound to MEDI8897 | | 分子名称: | CHLORIDE ION, Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, ... | | 著者 | McLellan, J.S. | | 登録日 | 2016-12-26 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
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