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8IO5
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BU of 8io5 by Molmil
Herg1a-herg1b closed state 2
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Zhang, M.F.
登録日2023-03-10
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of Herg1a-herg1b open state
To Be Published
8IOB
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BU of 8iob by Molmil
Herg1a-herg1b closed state 1
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Zhang, M.F.
登録日2023-03-10
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of Herg1a-herg1b closed state 1
To Be Published
5F17
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BU of 5f17 by Molmil
Structure of EAV NSP11 K170A mutant at 3.19A
分子名称: Non-structural protein 11
著者Zhang, M.F, Chen, Z.Z.
登録日2015-11-30
公開日2016-11-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of EAV NSP11 K170A mutant at 3.19A
To Be Published
8IFU
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BU of 8ifu by Molmil
HcCCR in NaCl
分子名称: (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, HcCCR, RETINAL, ...
著者Zhang, M.F.
登録日2023-02-19
公開日2024-02-28
実験手法ELECTRON MICROSCOPY (2.37 Å)
主引用文献Structure of HcCCR
To Be Published
8IO4
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BU of 8io4 by Molmil
Herg1a-herg1b open state
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Zhang, M.F.
登録日2023-03-10
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of Herg1a-herg1b open state
To Be Published
7XTK
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BU of 7xtk by Molmil
Cryo-EM structure of SLC19A1
分子名称: Reduced folate transporter
著者Zhang, M.F, Shan, Y.Y.
登録日2022-05-17
公開日2023-06-21
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structure of human SLC19A1.
To Be Published
7XYM
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BU of 7xym by Molmil
The pre-fusion structure of Thogotovirus dhori envelope glycoprotein
分子名称: Envelope glycoprotein
著者Shan, Y.Y, Zhang, M.F, Pei, D.Q.
登録日2022-06-01
公開日2023-07-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Pre- and post-fusion class III glycoprotein structures reveal viral fusion mechanism
To Be Published
7V2J
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BU of 7v2j by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 33
分子名称: Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-4-methoxy-benzenesulfonamide
著者Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y.
登録日2021-08-09
公開日2022-08-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia.
Acta Pharmacol.Sin., 43, 2022
7V1U
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BU of 7v1u by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZJ12
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide
著者Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y.
登録日2021-08-06
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia.
Acta Pharmacol.Sin., 43, 2022
5EYI
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BU of 5eyi by Molmil
Structure of PRRSV apo-NSP11 at 2.16A
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, Non-structural protein 11, ...
著者Zhang, M.F, Chen, Z.
登録日2015-11-25
公開日2016-10-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural Biology of the Arterivirus nsp11 Endoribonucleases.
J. Virol., 91, 2017
5HBZ
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BU of 5hbz by Molmil
Structure of EAV NSP11 K170A mutant at 3.10A
分子名称: Non-structural protein 11
著者Zhang, M.F, Chen, Z.Z.
登録日2016-01-04
公開日2016-10-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Biology of the Arterivirus nsp11 Endoribonucleases.
J. Virol., 91, 2017
5HC1
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BU of 5hc1 by Molmil
Structure of EAV NSP11 H141A mutant at 3.10A
分子名称: Non-structural protein 11
著者Zhang, M.F, Chen, Z.Z.
登録日2016-01-04
公開日2016-10-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Biology of the Arterivirus nsp11 Endoribonucleases.
J. Virol., 91, 2017
8GRO
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BU of 8gro by Molmil
AtOSCA3.1 contracted state
分子名称: CSC1-like protein ERD4
著者Zhang, M.F.
登録日2022-09-02
公開日2023-06-14
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
8GSO
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BU of 8gso by Molmil
AtOSCA3.1 channel extended state
分子名称: CSC1-like protein ERD4
著者Zhang, M.F.
登録日2022-09-06
公開日2023-06-14
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
8GRN
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BU of 8grn by Molmil
AtOSCA1.1 extended state
分子名称: Protein OSCA1, [1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE
著者Zhang, M.F.
登録日2022-09-02
公開日2023-06-14
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
8GRS
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BU of 8grs by Molmil
human TMEM63A
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CSC1-like protein 1
著者Zhang, M.F.
登録日2022-09-02
公開日2023-06-14
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
7YJ0
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BU of 7yj0 by Molmil
Structural basis of oxepinone formation by a flavin-monooxygenase VibO
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, VibO
著者Zhang, M.F, Pan, L.F.
登録日2022-07-18
公開日2023-05-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献A flavin-monooxygenase catalyzing oxepinone formation and the complete biosynthesis of vibralactone.
Nat Commun, 14, 2023
7YIG
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BU of 7yig by Molmil
Human KCNH5 pre-open state 2
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIF
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BU of 7yif by Molmil
Human KCNH5 pre-open state 1
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIE
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BU of 7yie by Molmil
Human KCNH5-closed state 2
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YID
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BU of 7yid by Molmil
Human KCNH5 closed state 1
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIH
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BU of 7yih by Molmil
Human KCNH5 open state
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIJ
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BU of 7yij by Molmil
Human KCNH5 pore dilation but the non-conducting state
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7DHS
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BU of 7dhs by Molmil
Crystal Structure Analysis of the BRD4
分子名称: 6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1R)-1-phenylethyl]benzo[cd]indol-2-one, Bromodomain-containing protein 4
著者Wu, T, Xiang, Q, Wang, C, Wu, C, Zhang, C, Zhang, M, Liu, Z, Zhang, Y, Xiao, L, Xu, Y.
登録日2020-11-17
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Y06014 is a selective BET inhibitor for the treatment of prostate cancer.
Acta Pharmacol.Sin., 42, 2021

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件を2024-06-12に公開中

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