8IO5
 
 | | Herg1a-herg1b closed state 2 | | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | | 著者 | Zhang, M.F. | | 登録日 | 2023-03-10 | | 公開日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of Herg1a-herg1b open state
To Be Published
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8IOB
 | | Herg1a-herg1b closed state 1 | | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | | 著者 | Zhang, M.F. | | 登録日 | 2023-03-10 | | 公開日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of Herg1a-herg1b closed state 1
To Be Published
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5F17
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8IFU
 | | HcCCR in NaCl | | 分子名称: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, HcCCR, RETINAL, ... | | 著者 | Zhang, M.F. | | 登録日 | 2023-02-19 | | 公開日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.37 Å) | | 主引用文献 | Structure of HcCCR
To Be Published
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8IO4
 | | Herg1a-herg1b open state | | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | | 著者 | Zhang, M.F. | | 登録日 | 2023-03-10 | | 公開日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of Herg1a-herg1b open state
To Be Published
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7XTK
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7XYM
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7V2J
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 33 | | 分子名称: | Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-4-methoxy-benzenesulfonamide | | 著者 | Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y. | | 登録日 | 2021-08-09 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia.
Acta Pharmacol.Sin., 43, 2022
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7V1U
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZJ12 | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide | | 著者 | Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y. | | 登録日 | 2021-08-06 | | 公開日 | 2022-08-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia.
Acta Pharmacol.Sin., 43, 2022
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5EYI
 | | Structure of PRRSV apo-NSP11 at 2.16A | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, Non-structural protein 11, ... | | 著者 | Zhang, M.F, Chen, Z. | | 登録日 | 2015-11-25 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Structural Biology of the Arterivirus nsp11 Endoribonucleases.
J. Virol., 91, 2017
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5HBZ
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5HC1
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8GRO
 | | AtOSCA3.1 contracted state | | 分子名称: | CSC1-like protein ERD4 | | 著者 | Zhang, M.F. | | 登録日 | 2022-09-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
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8GSO
 | | AtOSCA3.1 channel extended state | | 分子名称: | CSC1-like protein ERD4 | | 著者 | Zhang, M.F. | | 登録日 | 2022-09-06 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
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8GRN
 | | AtOSCA1.1 extended state | | 分子名称: | Protein OSCA1, [1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE | | 著者 | Zhang, M.F. | | 登録日 | 2022-09-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
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8GRS
 | | human TMEM63A | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CSC1-like protein 1 | | 著者 | Zhang, M.F. | | 登録日 | 2022-09-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
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7YJ0
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7YIG
 | | Human KCNH5 pre-open state 2 | | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | | 著者 | Zhang, M.F. | | 登録日 | 2022-07-16 | | 公開日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
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7YIF
 | | Human KCNH5 pre-open state 1 | | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | | 著者 | Zhang, M.F. | | 登録日 | 2022-07-16 | | 公開日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
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7YIE
 | | Human KCNH5-closed state 2 | | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | | 著者 | Zhang, M.F. | | 登録日 | 2022-07-16 | | 公開日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
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7YID
 | | Human KCNH5 closed state 1 | | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | | 著者 | Zhang, M.F. | | 登録日 | 2022-07-16 | | 公開日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
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7YIH
 | | Human KCNH5 open state | | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | | 著者 | Zhang, M.F. | | 登録日 | 2022-07-16 | | 公開日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
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7YIJ
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7DHS
 | | Crystal Structure Analysis of the BRD4 | | 分子名称: | 6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1R)-1-phenylethyl]benzo[cd]indol-2-one, Bromodomain-containing protein 4 | | 著者 | Wu, T, Xiang, Q, Wang, C, Wu, C, Zhang, C, Zhang, M, Liu, Z, Zhang, Y, Xiao, L, Xu, Y. | | 登録日 | 2020-11-17 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Y06014 is a selective BET inhibitor for the treatment of prostate cancer.
Acta Pharmacol.Sin., 42, 2021
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