8PVV
| Archaeoglobus fulgidus AfAgo complex with AfAgo-N protein (fAfAgo) bound with 30 nt RNA guide and 51 nt DNA target | 分子名称: | Archaeoglobus fulgidus AfAgo-N protein, DNA (51-MER), MAGNESIUM ION, ... | 著者 | Manakova, E.N, Zaremba, M, Pocevicuite, R, Golovinas, E, Sasnauskas, G, Zagorskaite, E, Silanskas, A. | 登録日 | 2023-07-18 | 公開日 | 2024-01-24 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein. Nucleic Acids Res., 52, 2024
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3ZI5
| Crystal STRUCTURE OF RESTRICTION ENDONUCLEASE BFII C-TERMINAL RECOGNITION DOMAIN IN COMPLEX WITH COGNATE DNA | 分子名称: | 5'-D(*AP*GP*CP*AP*CP*TP*GP*GP*GP*TP*CP*GP)-3', 5'-D(*CP*GP*AP*CP*CP*CP*AP*GP*TP*GP*CP*TP)-3', RESTRICTION ENDONUCLEASE | 著者 | Golovenko, D, Manakova, E, Zakrys, L, Zaremba, M, Sasnauskas, G, Grazulis, S, Siksnys, V. | 登録日 | 2013-01-03 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural Insight Into the Specificity of the B3 DNA-Binding Domains Provided by the Co-Crystal Structure of the C-Terminal Fragment of Bfii Restriction Enzyme Nucleic Acids Res., 42, 2014
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6XUP
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6XU0
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8QG0
| Archaeoglobus fulgidus AfAgo complex with AfAgo-N protein (fAfAgo) bound with 17 nt RNA guide and 17 nt DNA target | 分子名称: | AfAgo-N protein, DNA target 17 nt, Piwi protein, ... | 著者 | Manakova, E.N, Zaremba, M, Pocevicuite, R, Golovinas, E, Zagorskaite, E, Silanskas, A. | 登録日 | 2023-09-05 | 公開日 | 2024-01-24 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | 主引用文献 | The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein. Nucleic Acids Res., 52, 2024
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4ABT
| Crystal structure of Type IIF restriction endonuclease NgoMIV with cognate uncleaved DNA | 分子名称: | 5'-D(*TP*GP*CP*GP*CP*CP*GP*GP*CP*GP*CP)-3', CALCIUM ION, TYPE-2 RESTRICTION ENZYME NGOMIV | 著者 | Manakova, E.N, Grazulis, S, Zaremba, M, Tamulaitiene, G, Golovenko, D, Siksnys, V. | 登録日 | 2011-12-11 | 公開日 | 2011-12-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structure of Type Iif Restriction Endonuclease Ngomiv with Cognate Uncleaved DNA To be Published
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6F1S
| C-terminal domain of CglI restriction endonuclease H subunit | 分子名称: | 1,2-ETHANEDIOL, CglIIR protein, FORMIC ACID | 著者 | Tamulaitiene, G, Grigaitis, R, Zaremba, M, Silanskas, A. | 登録日 | 2017-11-23 | 公開日 | 2018-02-14 | 最終更新日 | 2019-01-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor. Nucleic Acids Res., 46, 2018
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8OLJ
| Crystal structure of Archaeoglobus fulgidus AfAgo-N protein representing N-L1-L2 domains | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETIC ACID, Archaeoglobus fulgidus AfAgo-N protein representing N-L1-L2 domains, ... | 著者 | Manakova, E.N, Zaremba, M, Grazulis, S. | 登録日 | 2023-03-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein. Nucleic Acids Res., 52, 2024
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8OLD
| Crystal structure of Archaeoglobus fulgidus AfAgo-N protein representing N-L1-L2 domains | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Archaeoglobus fulgidus AfAgo-N protein representing N-L1-L2 domains, CACODYLATE ION, ... | 著者 | Manakova, E.N, Zaremba, M, Grazulis, S. | 登録日 | 2023-03-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein. Nucleic Acids Res., 52, 2024
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8OK9
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4RCT
| Crystal structure of R-protein of NgoAVII restriction endonuclease | 分子名称: | Restriction endonuclease R.NgoVII | 著者 | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | 登録日 | 2014-09-17 | 公開日 | 2014-12-24 | 最終更新日 | 2014-12-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII. Nucleic Acids Res., 42, 2014
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4RD5
| Crystal structure of R.NgoAVII restriction endonuclease B3 domain with cognate DNA | 分子名称: | DNA (5'-D(*CP*CP*CP*TP*AP*AP*GP*CP*GP*GP*CP*AP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*TP*TP*GP*CP*CP*GP*CP*TP*TP*AP*GP*G)-3'), Restriction endonuclease R.NgoVII | 著者 | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | 登録日 | 2014-09-18 | 公開日 | 2014-12-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII. Nucleic Acids Res., 42, 2014
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4RDM
| Crystal structure of R.NgoAVII restriction endonuclease B3 domain with cognate DNA | 分子名称: | DNA (5'-D(*CP*CP*TP*AP*AP*GP*CP*GP*GP*CP*AP*AP*TP*CP*C)-3)', DNA (5'-D(*GP*GP*GP*AP*TP*TP*GP*CP*CP*GP*CP*TP*TP*AP*G)-3)', Restriction endonuclease R.NgoVII, ... | 著者 | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | 登録日 | 2014-09-19 | 公開日 | 2014-12-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII. Nucleic Acids Res., 42, 2014
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6T5T
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6TUO
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7BB5
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4ZSF
| Crystal structure of pre-specific restriction endonuclease BsaWI-DNA complex | 分子名称: | BsaWI endonuclease, CALCIUM ION, DNA, ... | 著者 | Tamulaitiene, G, Rutkauskas, M, Grazulis, S, Siksnys, V. | 登録日 | 2015-05-13 | 公開日 | 2015-10-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI. Nucleic Acids Res., 43, 2015
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3BM3
| Restriction endonuclease PspGI-substrate DNA complex | 分子名称: | CITRIC ACID, DNA (5'-D(*CP*AP*TP*CP*CP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*CP*TP*GP*GP*AP*T)-3'), ... | 著者 | Szczepanowski, R.H, Carpenter, M, Czapinska, H, Tamulaitis, G, Siksnys, V, Bhagwat, A, Bochtler, M. | 登録日 | 2007-12-12 | 公開日 | 2008-09-16 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A direct crystallographic demonstration that Type II restriction endonuclease PspGI flips nucleotides To be Published
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5DWB
| Crystal structure of specific restriction endonuclease AgeI-DNA complex | 分子名称: | DNA (5'-D(*TP*TP*CP*GP*AP*CP*CP*GP*GP*TP*CP*GP*A*)-3'), Type-2 restriction enzyme AgeI | 著者 | Tamulaitiene, G, Jovaisaite, V, Grazulis, S, Siksnys, V. | 登録日 | 2015-09-22 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA. Nucleic Acids Res., 45, 2017
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5DWA
| Crystal structure of pre-specific restriction endonuclease AgeI-DNA complex | 分子名称: | DNA (5'-D(*TP*CP*GP*AP*CP*CP*GP*GP*TP*CP*G*)-3'), Type-2 restriction enzyme AgeI | 著者 | Tamulaitiene, G, Jovaisaite, V, Grazulis, S, Siksnys, V. | 登録日 | 2015-09-22 | 公開日 | 2016-10-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA. Nucleic Acids Res., 45, 2017
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5DWC
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8BTO
| Helical structure of BcThsA in complex with 1''-3'gcADPR | 分子名称: | (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, NAD(+) hydrolase ThsA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Tamulaitiene, G, Sasnauskas, G, Sabonis, D. | 登録日 | 2022-11-29 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Activation of Thoeris antiviral system via SIR2 effector filament assembly. Nature, 627, 2024
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8BTN
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8BTP
| Helical structure of BcThsA in complex with 1''-3'gc(etheno)ADPR | 分子名称: | (1S,3S,4R,5R,7R,15R,16S,17R)-5-imidazo[2,1-f]purin-3-yl-10,12-bis(oxidanyl)-10,12-bis(oxidanylidene)-2,6,9,11,13,18-hexaoxa-10$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{3,7}]octadecane-4,16,17-triol, ETHENO-NAD, NAD(+) hydrolase ThsA | 著者 | Tamulaitiene, G, Sasnauskas, G, Sabonis, D. | 登録日 | 2022-11-29 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Activation of Thoeris antiviral system via SIR2 effector filament assembly. Nature, 627, 2024
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3V21
| Crystal structure of Type IIF restriction endonuclease Bse634I with cognate DNA | 分子名称: | DNA (5'-D(*TP*TP*CP*GP*AP*CP*CP*GP*GP*TP*CP*GP*A)-3'), Endonuclease Bse634IR | 著者 | Manakova, E.N, Grazulis, S, Golovenko, D, Tamulaitiene, G. | 登録日 | 2011-12-11 | 公開日 | 2012-04-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease. Nucleic Acids Res., 40, 2012
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