8J1Z
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6IGO
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6IGT
| MPZL1 mutant - V145G, Q146K, P147T and G148S | 分子名称: | Myelin protein zero-like protein 1 | 著者 | Yu, T. | 登録日 | 2018-09-26 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | 主引用文献 | Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1 Biochem. Biophys. Res. Commun., 506, 2018
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6IGW
| MPZL1 mutant - S86G, V145G, Q146K,P147T,G148S | 分子名称: | Myelin protein zero-like protein 1 | 著者 | Yu, T. | 登録日 | 2018-09-26 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.979 Å) | 主引用文献 | Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1 Biochem. Biophys. Res. Commun., 506, 2018
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8W51
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8KIE
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2MLK
| Three-dimensional structure of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae | 分子名称: | RstA | 著者 | Fang, P, Chen, S, Cheng, Y, Chang, C, Yu, T, Huang, T. | 登録日 | 2014-03-02 | 公開日 | 2014-07-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element. Nucleic Acids Res., 42, 2014
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4Y3I
| PAS-GAF fragment from Deinococcus radiodurans BphP assembled with BV - Y307S, low dose | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome | 著者 | Li, F, Burgie, E.S, Yu, T, Heroux, A, Schatz, G.C, Vierstra, R.D, Orville, A.M. | 登録日 | 2015-02-10 | 公開日 | 2015-05-20 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome. J.Am.Chem.Soc., 137, 2015
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4Y5F
| PAS-GAF fragment from Deinococcus radiodurans BphP assembled with BV - Y307S, high dose | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | 著者 | Li, F, Burgie, E.S, Yu, T, Heroux, A, Schatz, G.C, Vierstra, R.D, Orville, A.M. | 登録日 | 2015-02-11 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome. J.Am.Chem.Soc., 137, 2015
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6INE
| Crystal Structure of human ASH1L-MRG15 complex | 分子名称: | GLYCEROL, Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ... | 著者 | Hou, P, Huang, C, Liu, C.P, Yu, T, Yin, Y, Zhu, B, Xu, R.M. | 登録日 | 2018-10-25 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding. Structure, 27, 2019
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8A6M
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4CXP
| Structure of bifunctional endonuclease (AtBFN2) from Arabidopsis thaliana in complex with sulfate | 分子名称: | ENDONUCLEASE 2, PENTAETHYLENE GLYCOL, SULFATE ION, ... | 著者 | Yu, T.-F, Maestre-Reyna, M, Ko, C.-Y, Ko, T.-P, Sun, Y.-J, Lin, T.-Y, Shaw, J.-F, Wang, A.H.-J. | 登録日 | 2014-04-08 | 公開日 | 2014-07-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Structural Insights of the Ssdna Binding Site in the Multifunctional Endonuclease Atbfn2 from Arabidopsis Thaliana. Plos One, 9, 2014
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4CWM
| High-glycosylation crystal structure of the bifunctional endonuclease (AtBFN2) from Arabidopsis thaliana | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDONUCLEASE 2, ZINC ION, ... | 著者 | Yu, T.-F, Maestre-Reyna, M, Ko, C.-Y, Ko, T.-P, Sun, Y.-J, Lin, T.-Y, Shaw, J.-F, Wang, A.H.-J. | 登録日 | 2014-04-03 | 公開日 | 2014-07-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural Insights of the Ssdna Binding Site in the Multifunctional Endonuclease Atbfn2 from Arabidopsis Thaliana. Plos One, 9, 2014
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4CXO
| bifunctional endonuclease in complex with ssDNA | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ENDONUCLEASE 2, SULFATE ION, ... | 著者 | Yu, T.-F, Maestre-Reyna, M, Ko, C.-Y, Ko, T.-P, Sun, Y.-J, Lin, T.-Y, Shaw, J.-F, Wang, A.H.-J. | 登録日 | 2014-04-08 | 公開日 | 2014-07-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural Insights of the Ssdna Binding Site in the Multifunctional Endonuclease Atbfn2 from Arabidopsis Thaliana. Plos One, 9, 2014
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4CXV
| Structure of bifunctional endonuclease (AtBFN2) in complex with phosphate. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDONUCLEASE 2, ... | 著者 | Yu, T.-F, Maestre-Reyna, M, Ko, C.-Y, Ko, T.-P, Sun, Y.-J, Lin, T.-Y, Shaw, J.-F, Wang, A.H.-J. | 登録日 | 2014-04-09 | 公開日 | 2014-07-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Insights of the Ssdna Binding Site in the Multifunctional Endonuclease Atbfn2 from Arabidopsis Thaliana. Plos One, 9, 2014
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3MYG
| Aurora A Kinase complexed with SCH 1473759 | 分子名称: | 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol, Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL | 著者 | Hruza, A, Prosis, W, Ramanathan, L. | 登録日 | 2010-05-10 | 公開日 | 2010-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core. ACS Med Chem Lett, 1, 2010
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7YDG
| Crystal structure of human SARS2 catalytic domain with a disease related mutation | 分子名称: | Serine--tRNA ligase, mitochondrial | 著者 | Wu, S, Li, P, Zhou, X.L, Fang, P. | 登録日 | 2022-07-04 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease. Nucleic Acids Res., 50, 2022
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7YDF
| Crystal structure of human SARS2 catalytic domain | 分子名称: | Serine--tRNA ligase, mitochondrial | 著者 | Wu, S, Li, P, Zhou, X.L, Fang, P. | 登録日 | 2022-07-04 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease. Nucleic Acids Res., 50, 2022
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2W4P
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7N8T
| Crystal Structure of AMP-bound Human JNK2 | 分子名称: | ADENOSINE MONOPHOSPHATE, HEXAETHYLENE GLYCOL, Mitogen-activated protein kinase 9 | 著者 | Li, L, Gurbani, D, Westover, K.D. | 登録日 | 2021-06-15 | 公開日 | 2022-06-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. J.Med.Chem., 66, 2023
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2W4C
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2W4D
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3H42
| Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody | 分子名称: | Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ... | 著者 | Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E. | 登録日 | 2009-04-17 | 公開日 | 2009-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc.Natl.Acad.Sci.USA, 106, 2009
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8ELC
| Human JNK2 bound to covalent inhibitor YL2056 | 分子名称: | 4-(dimethylamino)-N-{4-[(3S)-3-({4-[(8R)-2-phenylpyrazolo[1,5-a]pyridin-3-yl]pyrimidin-2-yl}amino)pyrrolidine-1-carbonyl]phenyl}butanamide, Mitogen-activated protein kinase 9 | 著者 | Li, L, Gurbani, D, Westover, K.D. | 登録日 | 2022-09-23 | 公開日 | 2023-06-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.072 Å) | 主引用文献 | Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. J.Med.Chem., 66, 2023
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3O7L
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