Loading
PDBj
メニューPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3CST
DownloadVisualize
BU of 3cst by Molmil
Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor E5E2
分子名称: Methylated Ruthenium Pyridocarbazole, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者Xie, P, Marmorstein, R.
登録日2008-04-10
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.
Acs Chem.Biol., 3, 2008
3CSF
DownloadVisualize
BU of 3csf by Molmil
Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor DW2
分子名称: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, RU-PYRIDOCARBAZOLE-2
著者Xie, P, Marmorstein, R.
登録日2008-04-09
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.
Acs Chem.Biol., 3, 2008
3Q4C
DownloadVisualize
BU of 3q4c by Molmil
Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292
分子名称: Serine/threonine-protein kinase B-raf, [(1,2,3,4,5,6-eta)-(1S,2R,3R,4R,5S,6S)-1-carboxycyclohexane-1,2,3,4,5,6-hexayl](chloro)(3-methyl-5,7-dioxo-6,7-dihydro-5H-pyrido[2,3-a]pyrrolo[3,4-c]carbazol-12-ide-kappa~2~N~1~,N~12~)ruthenium(1+)
著者Xie, P, Streu, C, Qin, J, Pregman, H, Pagano, N, Meggers, E, Marmorstein, R.
登録日2010-12-23
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase.
Biochemistry, 48, 2009
1AGN
DownloadVisualize
BU of 1agn by Molmil
X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE
分子名称: ACETATE ION, HUMAN SIGMA ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Hurley, T.D, Xie, P.
登録日1996-06-04
公開日1997-03-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity.
J.Biol.Chem., 272, 1997
4E26
DownloadVisualize
BU of 4e26 by Molmil
BRAF in complex with an organic inhibitor 7898734
分子名称: 5-chloro-7-[(R)-furan-2-yl(pyridin-2-ylamino)methyl]quinolin-8-ol, Serine/threonine-protein kinase B-raf
著者Qin, J, Xie, P, Ventocilla, C, Zhou, G, Vultur, A, Chen, Q, Herlyn, M, Winkler, J, Marmorstein, R.
登録日2012-03-07
公開日2012-05-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Identification of a Novel Family of BRAF(V600E) Inhibitors.
J.Med.Chem., 55, 2012
1ZMS
DownloadVisualize
BU of 1zms by Molmil
LMP1 Protein binds to TRAF3 as a structural CD40
分子名称: Latent membrane protein 1, TNF receptor associated factor 3
著者Wu, S.D, Xie, P, Welsh, K, Li, C, Ni, C.-Z, Zhu, X, Reed, J.C, Satterthwait, A.C, Bishop, G.A, Ely, K.R.
登録日2005-05-10
公開日2005-07-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献LMP1 protein from the Epstein Barr virus is a structural CD40 decoy in B lymphocytes fro binding to TRAF3
J.Biol.Chem., 39, 2005
3KVQ
DownloadVisualize
BU of 3kvq by Molmil
Crystal structure of VEGFR2 extracellular domain D7
分子名称: Vascular endothelial growth factor receptor 2
著者Yang, Y, Opatowsky, Y, Xie, P, Schlessinger, J.
登録日2009-11-30
公開日2010-02-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
Proc.Natl.Acad.Sci.USA, 107, 2010
1CW3
DownloadVisualize
BU of 1cw3 by Molmil
HUMAN MITOCHONDRIAL ALDEHYDE DEHYDROGENASE COMPLEXED WITH NAD+ AND MN2+
分子名称: MAGNESIUM ION, MANGANESE (II) ION, MITOCHONDRIAL ALDEHYDE DEHYDROGENASE, ...
著者Ni, L, Zhou, J, Hurley, T.D, Weiner, H.
登録日1999-08-25
公開日1999-08-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Human liver mitochondrial aldehyde dehydrogenase: three-dimensional structure and the restoration of solubility and activity of chimeric forms.
Protein Sci., 8, 1999
1AG8
DownloadVisualize
BU of 1ag8 by Molmil
ALDEHYDE DEHYDROGENASE FROM BOVINE MITOCHONDRIA
分子名称: ALDEHYDE DEHYDROGENASE
著者Steinmetz, C.G, Hurley, T.D.
登録日1997-04-03
公開日1997-10-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.
Structure, 5, 1997
1A4Z
DownloadVisualize
BU of 1a4z by Molmil
ALDEHYDE DEHYDROGENASE FROM BOVINE MITOCHONDRIA COMPLEX WITH NAD (REDUCED) AND SAMARIUM (III)
分子名称: ALDEHYDE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SAMARIUM (III) ION
著者Steinmetz, C.G, Hurley, T.D.
登録日1998-02-10
公開日1998-04-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.
Structure, 5, 1997
5MTW
DownloadVisualize
BU of 5mtw by Molmil
Mycobacterium tuberculosis Rv1957 SecB-like chaperone in complex with a ChAD peptide from Rv1956 HigA1 antitoxin
分子名称: Antitoxin HigA1, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Guillet, V, Mourey, L.
登録日2017-01-10
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural insights into chaperone addiction of toxin-antitoxin systems.
Nat Commun, 10, 2019

227344

件を2024-11-13に公開中

PDB statisticsPDBj update infoContact PDBjnumon