2KXQ
 
 | | Solution Structure of Smurf2 WW2 and WW3 bound to Smad7 PY motif containing peptide | | 分子名称: | E3 ubiquitin-protein ligase SMURF2, Smad7 PY motif containing peptide | | 著者 | Chong, A, Lin, H, Wrana, J, Forman-Kay, J.D. | | 登録日 | 2010-05-11 | | 公開日 | 2010-10-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.
Proc.Natl.Acad.Sci.USA, 107, 2010
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6UUO
 | | Crystal structure of BRAF kinase domain bound to the PROTAC P4B | | 分子名称: | N-(3-{5-[(1-acetylpiperidin-4-yl)(methyl)amino]-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl}-2,4-difluorophenyl)propane-1-sulfonamide, Serine/threonine-protein kinase B-raf | | 著者 | Maisonneuve, P, Posternak, G, Kurinov, I, Sicheri, F. | | 登録日 | 2019-10-30 | | 公開日 | 2020-06-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.288 Å) | | 主引用文献 | Functional characterization of a PROTAC directed against BRAF mutant V600E.
Nat.Chem.Biol., 16, 2020
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3RZ3
 | | Human Cdc34 E2 in complex with CC0651 inhibitor | | 分子名称: | 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, Ubiquitin-conjugating enzyme E2 R1 | | 著者 | Ceccarelli, D.F, Webb, D.R, Sicheri, F. | | 登録日 | 2011-05-11 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | An allosteric inhibitor of the human cdc34 ubiquitin conjugating enzyme
Cell(Cambridge,Mass.), 145, 2011
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