7QWD
 
 | |
7QWE
 | |
7QWA
 | |
7QWB
 | |
8BFD
 | | Racemic structure of PK-7 (310HD-U2U5) | | 分子名称: | 310HD-U2U5, D-310HD-U2U5, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kumar, P, Paterson, N.G, Woolfson, D.N. | | 登録日 | 2022-10-25 | | 公開日 | 2022-11-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | De novo design of discrete, stable 3 10 -helix peptide assemblies.
Nature, 607, 2022
|
|
8BFE
 | | A dimeric de novo coiled-coil assembly: PK-2 (CC-TypeN-LaUbUcLd) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CC-TypeN-LaUbUcLd, ... | | 著者 | Kumar, P, Paterson, N.G, Woolfson, D.N. | | 登録日 | 2022-10-25 | | 公開日 | 2022-11-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | De novo design of discrete, stable 3 10 -helix peptide assemblies.
Nature, 607, 2022
|
|
1EYM
 | | FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX | | 分子名称: | FK506 BINDING PROTEIN | | 著者 | Rollins, C.T, Rivera, V.M, Woolfson, D.N, Keenan, T, Hatada, M, Adams, S.E, Andrade, L.J, Yaeger, D, van Schravendijk, M.R, Holt, D.A, Gilman, M, Clackson, T. | | 登録日 | 2000-05-07 | | 公開日 | 2000-08-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A ligand-reversible dimerization system for controlling protein-protein interactions.
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
6EIK
 | | A de novo designed heptameric coiled coil CC-Hept-I24E | | 分子名称: | CC-Hept-I24E, FORMIC ACID, GLYCEROL | | 著者 | Rhys, G.G, Burton, A.J, Dawson, W.M, Thomas, F, Woolfson, D.N. | | 登録日 | 2017-09-19 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | De Novo-Designed alpha-Helical Barrels as Receptors for Small Molecules.
ACS Synth Biol, 7, 2018
|
|
6EIZ
 | | A de novo designed hexameric coiled coil CC-Hex2 with farnesol bound in the channel. | | 分子名称: | (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, CC-Hex2 | | 著者 | Rhys, G.G, Burton, A.J, Dawson, W.M, Thomas, F, Woolfson, D.N. | | 登録日 | 2017-09-19 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | De Novo-Designed alpha-Helical Barrels as Receptors for Small Molecules.
ACS Synth Biol, 7, 2018
|
|
9GF4
 | | CC-Hept-IV-hen2 variant peptide with Hendecad repeat substitution | | 分子名称: | CC-Hept-IV-hen2, GLYCEROL, SODIUM ION | | 著者 | Kurgan, K.W, Martin, F.J.O, Woolfson, D.N. | | 登録日 | 2024-08-08 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Exchange, promiscuity, and orthogonality in de novo designed coiled-coil peptide assemblies.
Chem Sci, 16, 2025
|
|
9GF2
 | | CC-Hex-hen2 variant peptide with Hendecad repeat substitution | | 分子名称: | CC-Hex2-hen2, PENTAETHYLENE GLYCOL | | 著者 | Kurgan, K.W, Martin, F.J.O, Woolfson, D.N. | | 登録日 | 2024-08-08 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Exchange, promiscuity, and orthogonality in de novo designed coiled-coil peptide assemblies.
Chem Sci, 16, 2025
|
|
9F5A
 | |
1SIF
 | | Crystal structure of a multiple hydrophobic core mutant of ubiquitin | | 分子名称: | ubiquitin | | 著者 | Benitez-Cardoza, C.G, Stott, K, Hirshberg, M, Went, H.M, Woolfson, D.N, Jackson, S.E. | | 登録日 | 2004-02-29 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Exploring sequence/folding space: folding studies on multiple hydrophobic core mutants of ubiquitin
Biochemistry, 43, 2004
|
|
2G0K
 | |
2G0L
 | | Solution Structure of Neocarzinostatin Apo-Protein with bound Flavone | | 分子名称: | 2-PHENYL-4H-CHROMEN-4-ONE, NEOCARZINOSTATIN | | 著者 | Muskett, F.W, Stoneman, R.G, Caddick, S, Woolfson, D.N. | | 登録日 | 2006-02-13 | | 公開日 | 2006-03-28 | | 最終更新日 | 2024-11-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synthetic Ligands for Apo-Neocarzinostatin
J.Am.Chem.Soc., 128, 2006
|
|
6YB1
 | | Crystal structure of an antiparallel octameric transmembrane coiled coil K2-CCTM-VbIc | | 分子名称: | GLYCINE, K2-CCTM-VbIc, NONAETHYLENE GLYCOL | | 著者 | Kratochvil, H.T, Liu, L, Scott, A.J, Woolfson, D.N, DeGrado, W.F. | | 登録日 | 2020-03-15 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Constructing ion channels from water-soluble alpha-helical barrels.
Nat.Chem., 13, 2021
|
|
6YAZ
 | |
6YB2
 | |
6YB0
 | |
7A1T
 | | A collapsed hexameric state of a de novo coiled-coil assembly: CC-Type2-(GgLaId)4-W19BrPhe. | | 分子名称: | ACETATE ION, CADMIUM ION, CC-Type2-(GgLaId)4-W19BrPhe, ... | | 著者 | Rhys, G.G, Brady, R.L, Woolfson, D.N. | | 登録日 | 2020-08-14 | | 公開日 | 2021-05-19 | | 最終更新日 | 2021-11-17 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states.
Chem Sci, 12, 2021
|
|
6ZT1
 | |
8A09
 | | A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(QgLaId)4 | | 分子名称: | A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(QgLaId)4, GLYCEROL | | 著者 | Martin, F.J.O, Rhys, G.G, Dawson, W.M, Woolfson, D.N. | | 登録日 | 2022-05-27 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
|
|
5LO3
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | 分子名称: | PPaOMe | | 著者 | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | 登録日 | 2016-08-08 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-11-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
|
|
5LO2
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | 分子名称: | PPaTyr | | 著者 | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | 登録日 | 2016-08-08 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-11-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
|
|
5LO4
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | 分子名称: | PPa-CH3 | | 著者 | Baker, E.G, Williams, C, Hudson, K.L, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | 登録日 | 2016-08-08 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-11-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
|
|
