6WN7
 
 | | Homo sapiens S100A5 | | 分子名称: | CALCIUM ION, Protein S100-A5 | | 著者 | Perkins, A, Harms, M.J, Wong, C.E, Wheeler, L.C. | | 登録日 | 2020-04-22 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Learning peptide recognition rules for a low-specificity protein.
Protein Sci., 29, 2020
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9C1R
 | | Crystal structure of mutant cMET D1228N kinase domain in complex with inhibitor compound 13 | | 分子名称: | GLYCEROL, Hepatocyte growth factor receptor, N-(2,5-difluoro-4-{[(1s,3S)-3-(1-methyl-1H-pyrazol-3-yl)cyclobutyl][(8R)-pyrazolo[1,5-a]pyrazin-4-yl]amino}phenyl)-2-(5-fluoropyridin-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide | | 著者 | Simpson, H, Wu, W.-I, Mou, T.-C. | | 登録日 | 2024-05-29 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy.
J.Med.Chem., 2024
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8U7X
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8U7W
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9BLG
 | | Crystal structure of non-receptor protein tyrosine phosphatase SHP2 in complex with PF-07284892 | | 分子名称: | (1S)-1'-{6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-1,2,4-triazin-3-yl}-1,3-dihydrospiro[indene-2,4'-piperidin]-1-amine, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Bester, S.M, Wu, W.-I, Mou, T.-C. | | 登録日 | 2024-04-30 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy.
Cancer Discov, 13, 2023
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