6WN7
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![BU of 6wn7 by Molmil](/molmil-images/mine/6wn7) | Homo sapiens S100A5 | 分子名称: | CALCIUM ION, Protein S100-A5 | 著者 | Perkins, A, Harms, M.J, Wong, C.E, Wheeler, L.C. | 登録日 | 2020-04-22 | 公開日 | 2020-09-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Learning peptide recognition rules for a low-specificity protein. Protein Sci., 29, 2020
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9C1R
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![BU of 9c1r by Molmil](/molmil-images/mine/9c1r) | Crystal structure of mutant cMET D1228N kinase domain in complex with inhibitor compound 13 | 分子名称: | GLYCEROL, Hepatocyte growth factor receptor, N-(2,5-difluoro-4-{[(1s,3S)-3-(1-methyl-1H-pyrazol-3-yl)cyclobutyl][(8R)-pyrazolo[1,5-a]pyrazin-4-yl]amino}phenyl)-2-(5-fluoropyridin-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide | 著者 | Simpson, H, Wu, W.-I, Mou, T.-C. | 登録日 | 2024-05-29 | 公開日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy. J.Med.Chem., 2024
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8U7X
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![BU of 8u7x by Molmil](/molmil-images/mine/8u7x) | |
8U7W
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9BLG
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![BU of 9blg by Molmil](/molmil-images/mine/9blg) | Crystal structure of non-receptor protein tyrosine phosphatase SHP2 in complex with PF-07284892 | 分子名称: | (1S)-1'-{6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-1,2,4-triazin-3-yl}-1,3-dihydrospiro[indene-2,4'-piperidin]-1-amine, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Bester, S.M, Wu, W.-I, Mou, T.-C. | 登録日 | 2024-04-30 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy. Cancer Discov, 13, 2023
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