8CGC
| Structure of CSF1R in complex with a pyrollopyrimidine (compound 23) | 分子名称: | (2S)-2-hydroxybutanedioic acid, GLYCEROL, Macrophage colony-stimulating factor 1 receptor, ... | 著者 | Aarhus, T.I, Bjornstad, F, Wolowczyk, C, Larsen, K.U, Rognstad, L, Leithaug, T, Unger, A, Habenberger, P, Wolff, A, Bjorkoy, G, Pridans, C, Eickhoff, J, Klebl, B, Hoff, B.H, Sundby, E. | 登録日 | 2023-02-03 | 公開日 | 2023-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.925 Å) | 主引用文献 | Synthesis and Development of Highly Selective Pyrrolo[2,3- d ]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form. J.Med.Chem., 66, 2023
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2L2Y
| Thiostrepton, epimer form of residue 9 | 分子名称: | Thiostrepton | 著者 | Jonker, H.R.A, Baumann, S, Wolf, A, Schoof, S, Hiller, F, Schulte, K.W, Kirschner, K.N, Schwalbe, H, Arndt, H.-D. | 登録日 | 2010-08-27 | 公開日 | 2011-02-02 | 最終更新日 | 2013-06-26 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew.Chem.Int.Ed.Engl., 50, 2011
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2L2X
| Thiostrepton, oxidized at CA-CB bond of residue 9 | 分子名称: | Thiostrepton | 著者 | Jonker, H.R.A, Baumann, S, Wolf, A, Schoof, S, Hiller, F, Schulte, K.W, Kirschner, K.N, Schwalbe, H, Arndt, H.-D. | 登録日 | 2010-08-27 | 公開日 | 2011-02-02 | 最終更新日 | 2013-06-26 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew.Chem.Int.Ed.Engl., 50, 2011
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2L2Z
| Thiostrepton, reduced at N-CA bond of residue 14 | 分子名称: | Thiostrepton | 著者 | Jonker, H.R.A, Baumann, S, Wolf, A, Schoof, S, Hiller, F, Schulte, K.W, Kirschner, K.N, Schwalbe, H, Arndt, H.-D. | 登録日 | 2010-08-27 | 公開日 | 2011-02-02 | 最終更新日 | 2013-06-26 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew.Chem.Int.Ed.Engl., 50, 2011
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2L2W
| Thiostrepton | 分子名称: | Thiostrepton | 著者 | Jonker, H.R.A, Baumann, S, Wolf, A, Schoof, S, Hiller, F, Schulte, K.W, Kirschner, K.N, Schwalbe, H, Arndt, H.-D. | 登録日 | 2010-08-27 | 公開日 | 2011-02-02 | 最終更新日 | 2013-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew.Chem.Int.Ed.Engl., 50, 2011
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1C6V
| SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H) | 分子名称: | PROTEIN (SIU89134), PROTEIN (SIV INTEGRASE) | 著者 | Chen, Z, Yan, Y, Munshi, S, Li, Y, Zruygay-Murphy, J, Xu, B, Witmer, M, Felock, P, Wolfe, A, Sardana, V, Emini, E.A, Hazuda, D, Kuo, L.C. | 登録日 | 1999-12-21 | 公開日 | 2000-12-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform. J.Mol.Biol., 296, 2000
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5W2M
| APOBEC3F Catalytic Domain Complex with a Single-Stranded DNA | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION | 著者 | Fang, Y, Xiao, X, Li, S.-X, Wolfe, A, Chen, X.S. | 登録日 | 2017-06-06 | 公開日 | 2017-12-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA. J. Mol. Biol., 430, 2018
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5W45
| Crystal structure of APOBEC3H | 分子名称: | APOBEC3H, ZINC ION | 著者 | Ito, F, Yang, H.J, Xiao, X, Li, S.X, Wolfe, A, Zirkle, B, Arutiunian, V, Chen, X.S. | 登録日 | 2017-06-09 | 公開日 | 2018-03-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.486 Å) | 主引用文献 | Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H. Sci Rep, 8, 2018
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3D6M
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3D6F
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3D6H
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1SI9
| Boiling stable protein isolated from Populus tremula | 分子名称: | GLYCEROL, stable protein 1 | 著者 | Almog, O, Gonzales, A, Shoseyov, O, Dgany, O, Sofer, O, Wolf, S.G. | 登録日 | 2004-02-29 | 公開日 | 2004-09-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | The Structural Basis of the Thermostability of SP1, a Novel Plant (Populus tremula) Boiling Stable Protein. J.Biol.Chem., 279, 2004
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3ED8
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7OBH
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7OBX
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7OBY
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7OBG
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7OBS
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5JCY
| Spir2-GTBM bound to MyoVa-GTD | 分子名称: | Protein spire homolog 2, Unconventional myosin-Va | 著者 | Pylypenko, O, Malherbes, G, Welz, T, Kerkhoff, E, Houdusse, A. | 登録日 | 2016-04-15 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes. Elife, 5, 2016
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5JCZ
| Rab11 bound to MyoVa-GTD | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Pylypenko, O, Attanda, W, Gauquelin, C, Malherbes, G, Houdusse, A. | 登録日 | 2016-04-15 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.056 Å) | 主引用文献 | Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes. Elife, 5, 2016
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1TR0
| Crystal Structure of a boiling stable protein SP1 | 分子名称: | GLYCEROL, stable protein 1 | 著者 | Almog, O, Gonzalez, A, Sofer, O, Dgany, O, Shoseyov, O. | 登録日 | 2004-06-18 | 公開日 | 2004-09-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structural basis of the thermostability of SP1, a novel plant (Populus tremula) boiling stable protein J.Biol.Chem., 279, 2004
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3IW6
| Human p38 MAP Kinase in Complex with a Benzylpiperazin-Pyrrol | 分子名称: | Mitogen-activated protein kinase 14, ethyl 4-[(4-benzylpiperazin-1-yl)carbonyl]-1-ethyl-3,5-dimethyl-1H-pyrrole-2-carboxylate, octyl beta-D-glucopyranoside | 著者 | Gruetter, C, Simard, J.R, Rauh, D. | 登録日 | 2009-09-02 | 公開日 | 2009-11-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38alpha J.Am.Chem.Soc., 131, 2009
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3IW5
| Human p38 MAP Kinase in Complex with an Indole Derivative | 分子名称: | Mitogen-activated protein kinase 14, N-[2-(3-{[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]sulfanyl}-1H-indol-1-yl)ethyl]-3-(trifluoromethyl)benzamide, octyl beta-D-glucopyranoside | 著者 | Gruetter, C, Simard, J.R, Rauh, D. | 登録日 | 2009-09-02 | 公開日 | 2009-11-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38alpha J.Am.Chem.Soc., 131, 2009
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3IW8
| Structure of Inactive Human p38 MAP Kinase in Complex with a Thiazole-Urea | 分子名称: | 1-{4-[(1S)-1-amino-2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-(3-chloro-4-fluorophenyl)urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | 著者 | Gruetter, C, Simard, J.R, Rauh, D. | 登録日 | 2009-09-02 | 公開日 | 2009-11-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38alpha J.Am.Chem.Soc., 131, 2009
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3IW7
| Human p38 MAP Kinase in Complex with an Imidazo-pyridine | 分子名称: | 2-({4-[(4-benzylpiperidin-1-yl)carbonyl]benzyl}sulfanyl)-3H-imidazo[4,5-c]pyridine, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | 著者 | Gruetter, C, Simard, J.R, Rauh, D. | 登録日 | 2009-09-02 | 公開日 | 2009-11-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38alpha J.Am.Chem.Soc., 131, 2009
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