3C1Y
 
 | | Structure of bacterial DNA damage sensor protein with co-purified and co-crystallized ligand | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DNA integrity scanning protein disA | | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | | 登録日 | 2008-01-24 | | 公開日 | 2008-05-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates
Mol.Cell, 30, 2008
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3C21
 | | Structure of a bacterial DNA damage sensor protein with reaction product | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DNA integrity scanning protein disA | | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | | 登録日 | 2008-01-24 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates
Mol.Cell, 30, 2008
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3C23
 | | Structure of a bacterial DNA damage sensor protein with non-reactive Ligand | | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, DNA integrity scanning protein disA | | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | | 登録日 | 2008-01-24 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates
Mol.Cell, 30, 2008
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3C1Z
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4NQI
 | | Structure of the N-terminal I-BAR domain (1-259) of D.Discoideum IBARa | | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, SH3 domain-containing protein | | 著者 | Witte, G, Faix, J, Runge-Wollmann, P. | | 登録日 | 2013-11-25 | | 公開日 | 2014-02-05 | | 最終更新日 | 2014-04-02 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | The inverse BAR domain protein IBARa drives membrane remodeling to control osmoregulation, phagocytosis and cytokinesis.
J.Cell.Sci., 127, 2014
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5O7F
 | | Structure of the inactive T.maritima PDE (TM1595) D80N D154N mutant with GMP and Mn2+ | | 分子名称: | 1,2-ETHANEDIOL, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ... | | 著者 | Witte, G, Drexler, D, Mueller, M. | | 登録日 | 2017-06-08 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima.
Structure, 25, 2017
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5O70
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5O25
 | | Structure of wildtype T.maritima PDE (TM1595) in ligand-free state | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | | 著者 | Witte, G, Drexler, D, Mueller, M. | | 登録日 | 2017-05-19 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima.
Structure, 25, 2017
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5O58
 | | Structure of the inactive T.maritima PDE (TM1595) D80N D154N mutant with substrate 5'-pApG | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | | 著者 | Witte, G, Drexler, D, Mueller, M. | | 登録日 | 2017-06-01 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima.
Structure, 25, 2017
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5O1U
 | | Structure of wildtype T.maritima PDE (TM1595) with AMP and Mn2+ | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... | | 著者 | Witte, G, Drexler, D, Mueller, M. | | 登録日 | 2017-05-19 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima.
Structure, 25, 2017
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5O4Z
 | | Structure of the inactive T.maritima PDE (TM1595) D80N D154N mutant with substrate 5'-pApA | | 分子名称: | ADENOSINE-5'-MONOPHOSPHATE, CHLORIDE ION, DHH/DHHA1-type phosphodiesterase TM1595, ... | | 著者 | Witte, G, Drexler, D, Mueller, M. | | 登録日 | 2017-05-31 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima.
Structure, 25, 2017
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5EOM
 | | Structure of full-length human MAB21L1 with bound CTP | | 分子名称: | CITRIC ACID, CYTIDINE-5'-TRIPHOSPHATE, Protein mab-21-like 1, ... | | 著者 | de Oliveira Mann, C.C, Witte, G, Hopfner, K.-P. | | 登録日 | 2015-11-10 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.
Sci Rep, 6, 2016
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5EOG
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7OZ3
 | | S. agalactiae BusR in complex with its busA-promotor DNA | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GntR family transcriptional regulator, pBusA_for, ... | | 著者 | Bandera, A.M, Witte, G. | | 登録日 | 2021-06-25 | | 公開日 | 2021-08-11 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | | 主引用文献 | BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture.
Nucleic Acids Res., 49, 2021
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4WK1
 | | Crystal structure of Staphylococcus aureus PstA in complex with c-di-AMP | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, PstA | | 著者 | Mueller, M, Hopfner, K.-P, Witte, G. | | 登録日 | 2014-10-01 | | 公開日 | 2014-11-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | c-di-AMP recognition by Staphylococcus aureus PstA.
Febs Lett., 589, 2015
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4WK3
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4YVZ
 | | Structure of Thermotoga maritima DisA in complex with 3'-dATP/Mn2+ | | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, DNA integrity scanning protein DisA, MANGANESE (II) ION | | 著者 | Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G. | | 登録日 | 2015-03-20 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | | 主引用文献 | Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
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4ON9
 | | DECH box helicase domain | | 分子名称: | CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58, SULFATE ION | | 著者 | Deimling, T, Witte, G, Hopfner, K.P. | | 登録日 | 2014-01-28 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Crystal and solution structure of the human RIG-I SF2 domain
Acta Crystallogr.,Sect.F, 70, 2014
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4YXM
 | | Structure of Thermotoga maritima DisA D75N mutant with reaction product c-di-AMP | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA integrity scanning protein DisA | | 著者 | Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G. | | 登録日 | 2015-03-23 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
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4YXJ
 | | Structure of Thermotoga maritima DisA in complex with ApCpp | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA integrity scanning protein DisA | | 著者 | Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G. | | 登録日 | 2015-03-23 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
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3QB0
 | | Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 4, CALCIUM ION | | 著者 | Fenn, S, Breitsprecher, D, Gerhold, C.B, Witte, G, Faix, J, Hopfner, K.P. | | 登録日 | 2011-01-12 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.404 Å) | | 主引用文献 | Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin.
Embo J., 30, 2011
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3TJ1
 | | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | | 分子名称: | RNA polymerase I-specific transcription initiation factor RRN3 | | 著者 | Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. | | 登録日 | 2011-08-23 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
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4I1S
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2IHE
 | | Crystal structure of wild-type single-stranded DNA binding protein from Thermus aquaticus | | 分子名称: | Single-stranded DNA-binding protein | | 著者 | Fedorov, R, Witte, G, Urbanke, C, Manstein, D.J, Curth, U. | | 登録日 | 2006-09-26 | | 公開日 | 2007-01-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | 3D structure of Thermus aquaticus single-stranded DNA-binding protein gives insight into the functioning of SSB proteins.
Nucleic Acids Res., 34, 2006
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7B5W
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