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1YA9
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Crystal Structure of the 22kDa N-Terminal Fragment of Mouse Apolipoprotein E
分子名称: Apolipoprotein E
著者Peters-Libeu, C.A, Rutenber, E, Newhouse, Y, Hatters, D.M, Weisgraber, K.H.
登録日2004-12-17
公開日2005-06-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Engineering conformational destabilization into mouse apolipoprotein E. A model for a unique property of human apolipoprotein E4
J.Biol.Chem., 280, 2005
1IOJ
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HUMAN APOLIPOPROTEIN C-I, NMR, 18 STRUCTURES
分子名称: APOC-I
著者Rozek, A, Sparrow, J.T, Weisgraber, K.H, Cushley, R.J.
登録日1998-05-12
公開日1998-08-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Conformation of human apolipoprotein C-I in a lipid-mimetic environment determined by CD and NMR spectroscopy.
Biochemistry, 38, 1999
4DCQ
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Crystal Structure of the Fab Fragment of 3B5H10, an Antibody-Specific for Extended Polyglutamine Repeats (orthorhombic form)
分子名称: 1,2-ETHANEDIOL, 3B5H10 FAB Heavy Chain, 3B5H10 FAB Light Chain
著者Peters-Libeu, C.A, Tran, T, Finkbeiner, S, Weisgraber, K.
登録日2012-01-18
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.
J.Mol.Biol., 421, 2012
3S96
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Crystal structure of 3B5H10
分子名称: 3B5H10 FAB heavy chain, 3B5H10 FAB light chain
著者Weisgraber, K, Peters-Libeu, C, Rutenber, E, Newhouse, Y, Finkbeiner, S.
登録日2011-05-31
公開日2012-02-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.
J.Mol.Biol., 421, 2012
1LE4
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STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E
分子名称: APOLIPOPROTEIN E4
著者Wilson, C, Agard, D.A.
登録日1991-08-22
公開日1992-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms.
J.Biol.Chem., 269, 1994
1LE2
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STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E
分子名称: APOLIPOPROTEIN E2
著者Wilson, C, Agard, D.A.
登録日1991-08-22
公開日1992-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein.
Structure, 2, 1994
1NFN
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APOLIPOPROTEIN E3 (APOE3)
分子名称: APOLIPOPROTEIN E3
著者Rupp, B, Parkin, S.
登録日1996-07-17
公開日1997-01-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia.
Nat.Struct.Biol., 3, 1996
1OR3
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APOLIPOPROTEIN E3 (APOE3), TRIGONAL TRUNCATION MUTANT 165
分子名称: PROTEIN (APOLIPOPROTEIN E)
著者Rupp, B, Segelke, B.W.
登録日1998-12-01
公開日2000-05-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding.
Protein Sci., 9, 2000
1OR2
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APOLIPOPROTEIN E3 (APOE3) TRUNCATION MUTANT 165
分子名称: APOLIPOPROTEIN E
著者Rupp, B, Segelke, B.W, Forstner, M.
登録日1999-03-25
公開日2000-04-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding.
Protein Sci., 9, 2000
1NFO
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APOLIPOPROTEIN E2 (APOE2, D154A MUTATION)
分子名称: APOLIPOPROTEIN E2
著者Rupp, B, Parkin, S.
登録日1996-07-17
公開日1997-01-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia.
Nat.Struct.Biol., 3, 1996
1LPE
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THREE-DIMENSIONAL STRUCTURE OF THE LDL RECEPTOR-BINDING DOMAIN OF HUMAN APOLIPOPROTEIN E
分子名称: APOLIPOPROTEIN E3
著者Wilson, C, Agard, D.A.
登録日1991-08-22
公開日1992-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E.
Science, 252, 1991
1B68
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APOLIPOPROTEIN E4 (APOE4), 22K FRAGMENT
分子名称: APOLIPOPROTEIN E
著者Rupp, B, Peters-Libeu, C.
登録日1999-01-21
公開日2001-07-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interaction of the N-terminal domain of apolipoprotein E4 with heparin.
Biochemistry, 40, 2001
1BZ4
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APOLIPOPROTEIN E3 (APO-E3), TRUNCATION MUTANT 165
分子名称: PROTEIN (APOLIPOPROTEIN E)
著者Rupp, B, Segelke, B.
登録日1998-11-05
公開日1998-11-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding.
Protein Sci., 9, 2000
12E8
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2E8 FAB FRAGMENT
分子名称: IGG1-KAPPA 2E8 FAB (HEAVY CHAIN), IGG1-KAPPA 2E8 FAB (LIGHT CHAIN)
著者Rupp, B, Trakhanov, S.
登録日1998-03-14
公開日1998-08-05
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a monoclonal 2E8 Fab antibody fragment specific for the low-density lipoprotein-receptor binding region of apolipoprotein E refined at 1.9 A.
Acta Crystallogr.,Sect.D, null, 1999

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