Search by PDB author - 日本蛋白質構造データバンク

English 日本語简体中文繁體中文 한국어

✖

ﾒﾆｭｰ

RCSB PDB PDBe BMRB Adv. Search Search help

Search by PDB author

Visualize

BU of 5amn by Molmil

The Discovery of 2-Substituted Phenol Quinazolines as Potent and Selective RET Kinase Inhibitors
分子名称:	4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
著者	Newton, R, Bowler, K, Burns, E.M, Chapman, P, Fairweather, E, Fritzl, S, Goldberg, K, Hamilton, N.M, Holt, S.V, Hopkins, G.V, Jones, S.D, Jordan, A.M, Lyons, A, McDonald, N.Q, Maguire, L.A, Mould, D.P, Purkiss, A.G, Small, H.F, Stowell, A, Thomson, G.J, Waddell, I.D, Waszkowycz, B, Watson, A.J, Ogilvie, D.J.
登録日	2015-03-11
公開日	2016-02-17
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2.57 Å)
主引用文献	The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity. Eur J Med Chem, 112, 2016

Visualize

BU of 2jj0 by Molmil

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M248 REPLACED WITH TRP (CHAIN M, AM248W)
分子名称:	BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ...
著者	Fyfe, P.K, Potter, J.A, Cheng, J, Williams, C.M, Watson, A.J, Jones, M.R.
登録日	2007-07-03
公開日	2007-09-04
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Structural Responses to Cavity-Creating Mutations in an Integral Membrane Protein. Biochemistry, 46, 2007

Visualize

BU of 2jiy by Molmil

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M149 REPLACED WITH TRP (CHAIN M, AM149W)
分子名称:	BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ...
著者	Fyfe, P.K, Potter, J.A, Cheng, J, Williams, C.M, Watson, A.J, Jones, M.R.
登録日	2007-07-03
公開日	2007-09-04
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural Responses to Cavity-Creating Mutations in an Integral Membrane Protein. Biochemistry, 46, 2007

Visualize

BU of 5kze by Molmil

N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus
分子名称:	GLYCEROL, N-acetylneuraminate lyase, SULFATE ION
著者	North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J.
登録日	2016-07-25
公開日	2017-01-11
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.74 Å)
主引用文献	Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Lett., 590, 2016

Visualize

BU of 5kzd by Molmil

N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus with bound sialic acid alditol
分子名称:	(2~{S},4~{S},5~{R},6~{R},7~{S},8~{R})-5-acetamido-2,4,6,7,8,9-hexakis(oxidanyl)nonanoic acid, N-acetylneuraminate lyase
著者	North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J.
登録日	2016-07-25
公開日	2017-01-11
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.334 Å)
主引用文献	Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Lett., 590, 2016

Visualize

BU of 5m0d by Molmil

Structure-based evolution of a hybrid steroid series of Autotaxin inhibitors
分子名称:	CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, GLYCEROL, ...
著者	Keune, W.-J, Heidebrecht, T, Perrakis, A.
登録日	2016-10-04
公開日	2017-08-16
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators. J. Med. Chem., 60, 2017

Visualize

BU of 5m0e by Molmil

Structure-based evolution of a hybrid steroid series of Autotaxin inhibitors
分子名称:	7alpha-hydroxycholesterol, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ...
著者	Keune, W.-J, Heidebrecht, T, Perrakis, A.
登録日	2016-10-04
公開日	2017-08-16
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators. J. Med. Chem., 60, 2017

Visualize

BU of 5m0m by Molmil

Structure-based evolution of a hybrid steroid series of Autotaxin inhibitors
分子名称:	(2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ...
著者	Keune, W.-J, Heidebrecht, T, Perrakis, A.
登録日	2016-10-05
公開日	2017-08-16
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators. J. Med. Chem., 60, 2017

Visualize

BU of 5m0s by Molmil

Structure-based evolution of a hybrid steroid series of Autotaxin inhibitors
分子名称:	CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, GLYCEROL, ...
著者	Keune, W.-J, Heidebrecht, T, Perrakis, A.
登録日	2016-10-05
公開日	2017-08-16
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators. J. Med. Chem., 60, 2017

Visualize

BU of 4ny9 by Molmil

Crystal Structure Of the Human PXR-LBD In Complex With N-{(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl}-3-hydroxy-3-methylbutanamide
分子名称:	GLYCEROL, N-{(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl}-3-hydroxy-3-methylbutanamide, Nuclear receptor subfamily 1 group I member 2
著者	Khan, J.A, Camac, D.M.
登録日	2013-12-10
公開日	2014-08-27
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Discovery of the CCR1 antagonist, BMS-817399, for the treatment of rheumatoid arthritis. J.Med.Chem., 57, 2014

Visualize

BU of 4hdv by Molmil

Crystal structure of S. pombe ATL1 in complex with damaged DNA containing 2,6-diaminopurine
分子名称:	5'-D(CPTPAPCPTPAPGPCPCPAPTPGPG)-3', 5'-D(GPCPCPAPTPGP(1AP)PCPTPAPGPTPA)-3', Alkyltransferase-like protein 1
著者	Tubbs, J.L, Tainer, J.A.
登録日	2012-10-02
公開日	2012-12-26
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.702 Å)
主引用文献	Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-{pi} interactions. Proc.Natl.Acad.Sci.USA, 109, 2012

Visualize

BU of 4hdu by Molmil

Crystal structure of S. pombe ATL1 in complex with damaged DNA containing 2-aminopurine
分子名称:	5'-D(CPTPAPCPTPAPGPCPCPAPTPGPG)-3', 5'-D(GPCPCPAPTPGP(2PR)PCPTPAPGPTPA)-3', Alkyltransferase-like protein 1
著者	Tubbs, J.L, Tainer, J.A.
登録日	2012-10-02
公開日	2012-12-26
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.848 Å)
主引用文献	Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-{pi} interactions. Proc.Natl.Acad.Sci.USA, 109, 2012

Visualize

BU of 5lqq by Molmil

Structure of Autotaxin (ENPP2) with LM350
分子名称:	3-(6-chloranyl-2-methyl-1-phenyl-indol-3-yl)sulfanylbenzoic acid, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ...
著者	Keune, W.J, Heidebrecht, T, Castelmur, E, Joosten, R.P, Perrakis, A.
登録日	2016-08-17
公開日	2016-12-28
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Structure-Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode. J. Med. Chem., 60, 2017

Visualize

BU of 3gx4 by Molmil

Crystal Structure Analysis of S. Pombe ATL in complex with DNA
分子名称:	Alkyltransferase-like protein 1, COBALT HEXAMMINE(III), DNA (5'-D(CPTPAPCPTPAPGPCPCPAPTPGP*G)-3'), ...
著者	Tubbs, J.L, Arvai, A.S, Tainer, J.A.
登録日	2009-04-01
公開日	2009-06-09
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature, 459, 2009

Visualize

BU of 3gyh by Molmil

Crystal Structure Analysis of S. Pombe ATL in complex with damaged DNA containing POB
分子名称:	1-PYRIDIN-3-YLBUTAN-1-ONE, Alkyltransferase-like protein 1, DNA (5'-D(CPTPAPCPTPAPGPCPCPAPTPGP*G)-3'), ...
著者	Tubbs, J.L, Arvai, A.S, Tainer, J.A, Shin, D.S.
登録日	2009-04-03
公開日	2009-06-16
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature, 459, 2009

Visualize

BU of 4enj by Molmil

Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-hydroxyethylguanine
分子名称:	Alkyltransferase-like protein 1, DNA (5'-D(CPTPAPCPTPAPGPCPCPAPTPGPG)-3'), DNA (5'-D(GPCPCPAPTPGP(EHG)PCPTPAPGPTPA)-3')
著者	Tubbs, J.L, Arvai, A.S, Tainer, J.A.
登録日	2012-04-13
公開日	2012-06-20
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (3.0989 Å)
主引用文献	Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines. Mol.Cell, 47, 2012

Visualize

BU of 4enm by Molmil

Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-benzylguanine
分子名称:	Alkyltransferase-like protein 1, DNA (5'-D(CPTPAPCPTPAPGPCPCPAPTPGPG)-3'), DNA (5'-D(GPCPCPAPTPGP(BZG)PCPTPAPGPTPA)-3')
著者	Tubbs, J.L, Arvai, A.S, Tainer, J.A.
登録日	2012-04-13
公開日	2012-06-20
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.8402 Å)
主引用文献	Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines. Mol.Cell, 47, 2012

Visualize

BU of 4enk by Molmil

Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-propylguanine
分子名称:	Alkyltransferase-like protein 1, DNA (5'-D(CPTPAPCPTPAPGPCPCPAPTPGPG)-3'), DNA (5'-D(GPCPCPAPTPGP(6PO)PCPTPAPGPTPA)-3')
著者	Tubbs, J.L, Arvai, A.S, Tainer, J.A.
登録日	2012-04-13
公開日	2012-06-20
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (3.0445 Å)
主引用文献	Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines. Mol.Cell, 47, 2012

Visualize

BU of 4enn by Molmil

Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-carboxymethylguanine
分子名称:	Alkyltransferase-like protein 1, RNA (5'-R(GPCPCPAPTPGP(C6G)PCPTPAPGPTP*A)-3')
著者	Tubbs, J.L, Arvai, A.S, Tainer, J.A.
登録日	2012-04-13
公開日	2012-06-20
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.8448 Å)
主引用文献	Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines. Mol.Cell, 47, 2012

Visualize

BU of 3gva by Molmil

Crystal Structure Analysis of S. Pombe ATL
分子名称:	Alkyltransferase-like protein 1
著者	Tubbs, J.L, Arvai, A.S, Tainer, J.A.
登録日	2009-03-30
公開日	2009-06-09
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature, 459, 2009

221051

件を2024-06-12に公開中

PDB statistics

PDBj update info

Contact PDBj

numon