7RDE
 
 | | Human Triose Phosphate Isomerase Q181P | | 分子名称: | BROMIDE ION, CALCIUM ION, Triosephosphate isomerase | | 著者 | VanDemark, A.P, Kowalski, J. | | 登録日 | 2021-07-09 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency.
Dis Model Mech, 15, 2022
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2R0Y
 | | Structure of the Rsc4 tandem bromodomain in complex with an acetylated H3 peptide | | 分子名称: | Chromatin structure-remodeling complex protein RSC4, Histone H3 peptide | | 著者 | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | 登録日 | 2007-08-21 | | 公開日 | 2007-10-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R0V
 | | Structure of the Rsc4 tandem bromodomain acetylated at K25 | | 分子名称: | Chromatin structure-remodeling complex protein RSC4, SULFATE ION | | 著者 | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | 登録日 | 2007-08-21 | | 公開日 | 2007-10-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R10
 | | Structure of an acetylated Rsc4 tandem bromodomain Histone Chimera | | 分子名称: | 1,2-ETHANEDIOL, Chromatin structure-remodeling complex protein RSC4, LINKER, ... | | 著者 | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | 登録日 | 2007-08-21 | | 公開日 | 2007-10-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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3BIP
 | | Crystal structure of yeast Spt16 N-terminal Domain | | 分子名称: | FACT complex subunit SPT16 | | 著者 | VanDemark, A.P, Xin, H, McCullough, L, Rawlins, R, Bentley, S, Heroux, A, David, S.J, Hill, C.P, Formosa, T. | | 登録日 | 2007-11-30 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits.
J.Biol.Chem., 283, 2008
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3BIQ
 | | Crystal structure of yeast Spt16 N-terminal Domain | | 分子名称: | FACT complex subunit SPT16, GLYCEROL | | 著者 | VanDemark, A.P, Xin, H, McCullough, L, Rawlins, R, Bentley, S, Heroux, A, David, S.J, Hill, C.P, Formosa, T. | | 登録日 | 2007-11-30 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits.
J.Biol.Chem., 283, 2008
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3BIT
 | | Crystal structure of yeast Spt16 N-terminal Domain | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, FACT complex subunit SPT16, ... | | 著者 | VanDemark, A.P, Xin, H, McCullough, L, Rawlins, R, Bentley, S, Heroux, A, David, S.J, Hill, C.P, Formosa, T. | | 登録日 | 2007-11-30 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits.
J.Biol.Chem., 283, 2008
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1JAT
 | | Mms2/Ubc13 Ubiquitin Conjugating Enzyme Complex | | 分子名称: | Ubiquitin-Conjugating Enzyme E2-17.5 KDA, Ubiquitin-Conjugating Enzyme Variant Mms2 | | 著者 | VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C. | | 登録日 | 2001-05-31 | | 公開日 | 2001-06-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
Cell(Cambridge,Mass.), 105, 2001
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1JBB
 | | Ubiquitin Conjugating Enzyme, Ubc13 | | 分子名称: | ubiquitin conjugating enzyme E2-17.5 KDA | | 著者 | VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C. | | 登録日 | 2001-06-03 | | 公開日 | 2001-06-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
Cell(Cambridge,Mass.), 105, 2001
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2GCJ
 | | Crystal Structure of the Pob3 middle domain | | 分子名称: | Hypothetical 63.0 kDa protein in DAK1-ORC1 intergenic region | | 著者 | VanDemark, A.P. | | 登録日 | 2006-03-14 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition.
Mol.Cell, 22, 2006
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2GCL
 | | Structure of the Pob3 Middle domain | | 分子名称: | CHLORIDE ION, Hypothetical 63.0 kDa protein in DAK1-ORC1 intergenic region | | 著者 | VanDemark, A.P. | | 登録日 | 2006-03-14 | | 公開日 | 2006-05-23 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition.
Mol.Cell, 22, 2006
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2R0S
 | | Crystal Structure of the Rsc4 tandem bromodomain | | 分子名称: | Chromatin structure-remodeling complex protein RSC4 | | 著者 | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | 登録日 | 2007-08-21 | | 公開日 | 2007-10-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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5VFZ
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2R3C
 | | Structure of the gp41 N-peptide in complex with the HIV entry inhibitor PIE1 | | 分子名称: | CHLORIDE ION, HIV entry inhibitor PIE1, YTTRIUM (III) ION, ... | | 著者 | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | 登録日 | 2007-08-29 | | 公開日 | 2007-10-02 | | 最終更新日 | 2018-08-08 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R5B
 | | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | | 分子名称: | HIV entry inhibitor PIE7, SULFATE ION, gp41 N-peptide | | 著者 | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | 登録日 | 2007-09-03 | | 公開日 | 2007-10-02 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R5D
 | | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HIV entry inhibitor PIE7, ... | | 著者 | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | 登録日 | 2007-09-03 | | 公開日 | 2007-10-02 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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5E8B
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5EMX
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8EXZ
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6UIH
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5F5P
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5F4Y
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4ZVJ
 | | Structure of human triose phosphate isomerase K13M | | 分子名称: | POTASSIUM ION, SODIUM ION, Triosephosphate isomerase | | 著者 | Amrich, C.G, Smith, C, Heroux, A, VanDemark, A.P. | | 登録日 | 2015-05-18 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6996 Å) | | 主引用文献 | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim. Biophys. Acta, 1852, 2015
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6NLH
 | | Structure of human triose phosphate isomerase R189A | | 分子名称: | BROMIDE ION, PHOSPHATE ION, SODIUM ION, ... | | 著者 | Richards, K.R, Roland, B.P, Palladino, M.J, VanDemark, A.P. | | 登録日 | 2019-01-08 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
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3V46
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