8Q40
| Crystal structure of cA4 activated Can2 in complex with a cleaved DNA substrate | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*CP*A)-3'), DUF1887 family protein, ... | 著者 | Jungfer, K, Sigg, A, Jinek, M. | 登録日 | 2023-08-04 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
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8Q42
| Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-A DNA | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*AP*AP*AP*A)-3'), DUF1887 family protein, ... | 著者 | Jungfer, K, Sigg, A, Jinek, M. | 登録日 | 2023-08-04 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
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8Q41
| Crystal structure of Can2 (E341A) bound to cA4 and TTTAAA ssDNA | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*TP*AP*AP*A)-3'), DUF1887 family protein, ... | 著者 | Jungfer, K, Sigg, A, Jinek, M. | 登録日 | 2023-08-04 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
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8Q43
| Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-C DNA | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*CP*CP*CP*CP*C)-3'), DUF1887 family protein, ... | 著者 | Jungfer, K, Sigg, A, Jinek, M. | 登録日 | 2023-08-04 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
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8Q44
| Crystal structure of cA4-bound Can2 (E364R) in complex with oligo-T DNA | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*TP*T)-3'), DUF1887 family protein, ... | 著者 | Jungfer, K, Sigg, A, Jinek, M. | 登録日 | 2023-08-04 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
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8Q3Y
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8Q3Z
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7UIN
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7UIM
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2JZY
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7B29
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7B2A
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7B2D
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7B26
| CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3 | 分子名称: | CirpA1, Properdin, alpha-D-mannopyranose, ... | 著者 | Lea, S.M, Johnson, S, Braunger, K. | 登録日 | 2020-11-26 | 公開日 | 2021-12-08 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure and function of a family of tick-derived complement inhibitors targeting properdin. Nat Commun, 13, 2022
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7B28
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6E6Z
| Structure of Wild Type Human Transthyretin in Complex with Tafamidis | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E73
| Structure of Human Transthyretin Val30Met Mutant in Complex with Diflunisal | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, ACETATE ION, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | 主引用文献 | Structural Variants of Transthyretin to be published
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6E72
| Structure of Human Transthyretin Val30Met Mutant in Complex with Tafamidis | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E78
| Structure of Human Transthyretin Asp38Ala Mutant in Complex with Diflunisal | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E70
| Structure of Wild Type Human Transthyretin in Complex with Diflunisal | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, CALCIUM ION, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E75
| Structure of Human Transthyretin Asp38Ala Mutant | 分子名称: | ACETATE ION, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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5NQ2
| 'Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting IAYERMCNI | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-04-25 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
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5NQ1
| Porcine (Sus scrofa) Major Histocompatibility Complex, class I, with human beta2 micro globulin, presenting DFEREGYSL | 分子名称: | 1,2-ETHANEDIOL, ASP-PHE-GLU-ARG-GLU-GLY-TYR-SER-LEU, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
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5NPZ
| Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting EFEDLTFLA | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-05-02 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
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5NQ3
| 'Porcine (Sus scrofa) Major Histocompatibility Complex, class I, with human beta2 micro globulin, presenting EFEDLTFLA | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-PHE-GLU-ASP-LEU-THR-PHE-LEU-ALA, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-04-25 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
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