8Q40
 
 | | Crystal structure of cA4 activated Can2 in complex with a cleaved DNA substrate | | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*CP*A)-3'), DUF1887 family protein, ... | | 著者 | Jungfer, K, Sigg, A, Jinek, M. | | 登録日 | 2023-08-04 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
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8Q41
 | | Crystal structure of Can2 (E341A) bound to cA4 and TTTAAA ssDNA | | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*TP*AP*AP*A)-3'), DUF1887 family protein, ... | | 著者 | Jungfer, K, Sigg, A, Jinek, M. | | 登録日 | 2023-08-04 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
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8Q42
 | | Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-A DNA | | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*AP*AP*AP*A)-3'), DUF1887 family protein, ... | | 著者 | Jungfer, K, Sigg, A, Jinek, M. | | 登録日 | 2023-08-04 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
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8Q43
 | | Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-C DNA | | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*CP*CP*CP*CP*C)-3'), DUF1887 family protein, ... | | 著者 | Jungfer, K, Sigg, A, Jinek, M. | | 登録日 | 2023-08-04 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
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8Q44
 | | Crystal structure of cA4-bound Can2 (E364R) in complex with oligo-T DNA | | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*TP*T)-3'), DUF1887 family protein, ... | | 著者 | Jungfer, K, Sigg, A, Jinek, M. | | 登録日 | 2023-08-04 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
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8Q3Z
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8Q3Y
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6FTJ
 | | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed 80S Ribosome | | 分子名称: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Braunger, K, Becker, T, Beckmann, R. | | 登録日 | 2018-02-22 | | 公開日 | 2018-03-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Science, 360, 2018
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7UIM
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7UIN
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6FTI
 | | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome | | 分子名称: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Braunger, K, Becker, T, Beckmann, R. | | 登録日 | 2018-02-22 | | 公開日 | 2018-03-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Science, 360, 2018
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2JZY
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7B29
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7B2A
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7B2D
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7B26
 | | CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3 | | 分子名称: | CirpA1, Properdin, alpha-D-mannopyranose, ... | | 著者 | Lea, S.M, Johnson, S, Braunger, K. | | 登録日 | 2020-11-26 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
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7B28
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6E73
 | | Structure of Human Transthyretin Val30Met Mutant in Complex with Diflunisal | | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, ACETATE ION, Transthyretin | | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | | 主引用文献 | Structural Variants of Transthyretin
to be published
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6E72
 | | Structure of Human Transthyretin Val30Met Mutant in Complex with Tafamidis | | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural Variants of Transthyretin
To Be Published
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6E78
 | | Structure of Human Transthyretin Asp38Ala Mutant in Complex with Diflunisal | | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | | 主引用文献 | Structural Variants of Transthyretin
To Be Published
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6E70
 | | Structure of Wild Type Human Transthyretin in Complex with Diflunisal | | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, CALCIUM ION, Transthyretin | | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | | 主引用文献 | Structural Variants of Transthyretin
To Be Published
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6E75
 | | Structure of Human Transthyretin Asp38Ala Mutant | | 分子名称: | ACETATE ION, Transthyretin | | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural Variants of Transthyretin
To Be Published
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6E6Z
 | | Structure of Wild Type Human Transthyretin in Complex with Tafamidis | | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Variants of Transthyretin
To Be Published
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5NPZ
 | | Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting EFEDLTFLA | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | | 登録日 | 2017-04-19 | | 公開日 | 2018-05-02 | | 最終更新日 | 2019-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig.
Plos Pathog., 14, 2018
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5NQ2
 | | 'Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting IAYERMCNI | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ... | | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | | 登録日 | 2017-04-19 | | 公開日 | 2018-04-25 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig.
Plos Pathog., 14, 2018
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