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7RCF
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BU of 7rcf by Molmil
Fourth stage reengineered variant of I-OnuI with stability enhancing substitutions
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Ubilla-Rodriguez, N.C, Werther, R.A, Stoddard, B.L.
登録日2021-07-07
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.233 Å)
主引用文献Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
7RCD
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BU of 7rcd by Molmil
Second stage reengineered variant of I-OnuI targeting human PD1 gene with activity enhancing substitutions
分子名称: CALCIUM ION, DNA (26-MER), I-OnuI_e-hPD1-c
著者Ubilla-Rodriguez, N.C, Werther, R.A, Stoddard, B.L.
登録日2021-07-07
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.448 Å)
主引用文献Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
7RCE
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BU of 7rce by Molmil
Third stage reengineered variant of I-OnuI with specificity enhancing substitutions
分子名称: CALCIUM ION, DNA (26-MER), I-OnuI_e-hPD1-d, ...
著者Ubilla-Rodriguez, N.C, Werther, R.A, Stoddard, B.L.
登録日2021-07-07
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
7RCC
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BU of 7rcc by Molmil
First stage engineered variant of I-OnuI after initial reassembly
分子名称: CALCIUM ION, DNA (26-MER), I-OnuI_e-hPD1-b
著者Ubilla-Rodriguez, N.C, Werther, R.A, Stoddard, B.L.
登録日2021-07-07
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
7RCG
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BU of 7rcg by Molmil
I-OnuI_e-hPD1-f final stage reengineered variant of I-OnuI
分子名称: CALCIUM ION, CHLORIDE ION, DNA (26-MER), ...
著者Smiley, A.T, Werther, R.A, Stoddard, B.L.
登録日2021-07-07
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.368 Å)
主引用文献Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
7T8L
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BU of 7t8l by Molmil
BrxR from Acinetobacter BREX type I phage restriction system
分子名称: 1,2-ETHANEDIOL, BrxR, CHLORIDE ION
著者Doyle, L, Kaiser, B, Stoddard, B.
登録日2021-12-16
公開日2022-05-18
最終更新日2022-06-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system.
Nucleic Acids Res., 50, 2022
7T8K
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BU of 7t8k by Molmil
BrxR from Acinetobacter BREX type I phage restriction system bound to DNA
分子名称: 1,2-ETHANEDIOL, BrxR, CHLORIDE ION, ...
著者Doyle, L, Kaiser, B, Stoddard, B.
登録日2021-12-16
公開日2022-05-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system.
Nucleic Acids Res., 50, 2022

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件を2024-10-09に公開中

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