5YQQ
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5YQI
| Crystal structure of the first StARkin domain of Lam2 | 分子名称: | Membrane-anchored lipid-binding protein YSP2 | 著者 | Tong, J, Im, Y.J. | 登録日 | 2017-11-06 | 公開日 | 2018-01-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5YQP
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5YS0
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5YQR
| Crystal structure of the PH-like domain of Lam6 | 分子名称: | Endolysin/Membrane-anchored lipid-binding protein LAM6 fusion protein, NONAETHYLENE GLYCOL | 著者 | Tong, J, Im, Y.J. | 登録日 | 2017-11-07 | 公開日 | 2018-01-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6IYB
| Structure of human ORP1 ANK - Rab7 complex | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Oxysterol-binding protein-related protein 1, ... | 著者 | Tong, J, Im, Y.J. | 登録日 | 2018-12-14 | 公開日 | 2019-03-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | 主引用文献 | Structural basis of human ORP1-Rab7 interaction for the late-endosome and lysosome targeting. PLoS ONE, 14, 2019
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7DEI
| Structure of human ORP3 ORD domain in complex with PI(4)P | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein-related protein 3 | 著者 | Tong, J, Tan, L, Im, Y.J. | 登録日 | 2020-11-04 | 公開日 | 2021-03-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins. Plos One, 16, 2021
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7DEJ
| Structure of human ORP3 ORD in apo-form | 分子名称: | Oxysterol-binding protein-related protein 3 | 著者 | Tong, J, Tan, L, Im, Y.J. | 登録日 | 2020-11-04 | 公開日 | 2021-03-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins. Plos One, 16, 2021
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4IAP
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4INQ
| Crystal structure of Osh3 ORD in complex with PI(4)P from Saccharomyces cerevisiae | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein homolog 3 | 著者 | Tong, J, Im, Y.J. | 登録日 | 2013-01-05 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins Structure, 21, 2013
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4IC4
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6L1D
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6L1M
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4R0Y
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7F65
| Bacetrial Cocaine Esterase with mutations T172R/G173Q/V116K/S117A/A51L, bound to benzoic acid | 分子名称: | BENZOIC ACID, Cocaine esterase, SULFATE ION | 著者 | Ouyang, P.F, Zhang, Y, Tong, J. | 登録日 | 2021-06-24 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase. Angew.Chem.Int.Ed.Engl., 60, 2021
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7V5N
| Crystal structure of Fab fragment of bevacizumab bound to DNA aptamer | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*GP*TP*TP*GP*GP*TP*GP*GP*TP*AP*GP*TP*TP*AP*CP*GP*TP*TP*CP*GP*C)-3'), IMIDAZOLE, ... | 著者 | Hishiki, A, Tong, J, Todoroki, K, Hashimoto, H. | 登録日 | 2021-08-17 | 公開日 | 2022-02-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection. Biosens.Bioelectron., 203, 2022
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5YQJ
| Crystal structure of the first StARkin domain of Lam4 | 分子名称: | Membrane-anchored lipid-binding protein LAM4 | 著者 | Im, Y.J, Tong, J.S. | 登録日 | 2017-11-06 | 公開日 | 2018-01-31 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8DSX
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8HRD
| Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant in complex with IMCAS74 Fab and W14 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS74 Fab heavy chain, IMCAS74 Fab light chain, ... | 著者 | Zhao, R.C, Wu, L.L, Han, P. | 登録日 | 2022-12-15 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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6DJ9
| Structure of the USP15 DUSP domain in complex with a high-affinity Ubiquitin Variant (UbV) | 分子名称: | Ubiquitin Variant UbV 15.D, Ubiquitin carboxyl-terminal hydrolase 15 | 著者 | Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. | 登録日 | 2018-05-24 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
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7ZLY
| Crystal structure of human GPCR Niacin receptor (HCA2) expressed from Spodoptera frugiperda | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, OLEIC ACID | 著者 | Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, FiBerto, J.F, Wu, L.J, Tong, J.H, Han, G.W, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J. | 登録日 | 2022-04-17 | 公開日 | 2023-04-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural insights into the human niacin receptor HCA2-G i signalling complex. Nat Commun, 14, 2023
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7ZL9
| Crystal structure of human GPCR Niacin receptor (HCA2) | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, ... | 著者 | Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, Han, G.W, FiBerto, J.F, Wu, L.J, Tong, J.H, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J. | 登録日 | 2022-04-14 | 公開日 | 2023-04-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural insights into the human niacin receptor HCA2-G i signalling complex. Nat Commun, 14, 2023
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4N9N
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7T1L
| Crystal structure of a superbinder Fes SH2 domain (sFesS) in complex with a high affinity phosphopeptide | 分子名称: | CHLORIDE ION, SODIUM ION, Synthetic phosphotyrosine-containing Ezrin-derived peptide, ... | 著者 | Martyn, G.D, Singer, A.U, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-12-02 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
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7T1K
| Crystal structure of a superbinder Fes SH2 domain (sFes1) in complex with a high affinity phosphopeptide | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MALONATE ION, ... | 著者 | Martyn, G.D, Singer, A.U, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-12-02 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
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