1K4U
 
 | | Solution structure of the C-terminal SH3 domain of p67phox complexed with the C-terminal tail region of p47phox | | 分子名称: | PHAGOCYTE NADPH OXIDASE SUBUNIT P47PHOX, PHAGOCYTE NADPH OXIDASE SUBUNIT P67PHOX | | 著者 | Kami, K, Takeya, R, Sumimoto, H, Kohda, D. | | 登録日 | 2001-10-08 | | 公開日 | 2002-04-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p.
EMBO J., 21, 2002
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1Q1O
 | | Solution Structure of the PB1 Domain of Cdc24p (Long Form) | | 分子名称: | Cell division control protein 24 | | 著者 | Yoshinaga, S, Kohjima, M, Ogura, K, Yokochi, M, Takeya, R, Ito, T, Sumimoto, H, Inagaki, F. | | 登録日 | 2003-07-22 | | 公開日 | 2003-10-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The PB1 domain and the PC motif-containing region are structurally similar protein binding modules
EMBO J., 22, 2003
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1WMH
 | | Crystal structure of a PB1 domain complex of Protein kinase c iota and Par6 alpha | | 分子名称: | Partitioning defective-6 homolog alpha, Protein kinase C, iota type | | 著者 | Hirano, Y, Yoshinaga, S, Suzuki, N.N, Horiuchi, M, Kohjima, M, Takeya, R, Sumimoto, H, Inagaki, F. | | 登録日 | 2004-07-09 | | 公開日 | 2004-12-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a Cell Polarity Regulator, a Complex between Atypical PKC and Par6 PB1 Domains
J.Biol.Chem., 280, 2005
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2DYB
 | | The crystal structure of human p40(phox) | | 分子名称: | Neutrophil cytosol factor 4 | | 著者 | Honbou, K. | | 登録日 | 2006-09-08 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding.
Embo J., 26, 2007
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1WLP
 | | Solution Structure Of The P22Phox-P47Phox Complex | | 分子名称: | Cytochrome b-245 light chain, Neutrophil cytosol factor 1 | | 著者 | Ogura, K, Torikai, S, Saikawa, K, Yuzawa, S, Sumimoto, H, Inagaki, F. | | 登録日 | 2004-06-29 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide
J.Biol.Chem., 281, 2006
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7YV1
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ... | | 著者 | Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A. | | 登録日 | 2022-08-18 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.454 Å) | | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
J.Am.Chem.Soc., 145, 2023
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7YUZ
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784 | | 分子名称: | AP8784, GUANOSINE-5'-DIPHOSPHATE, IODIDE ION, ... | | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | | 登録日 | 2022-08-18 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.878 Å) | | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
J.Am.Chem.Soc., 145, 2023
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8JJS
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | | 登録日 | 2023-05-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | | 主引用文献 | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor.
J.Am.Chem.Soc., 145, 2023
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