7RZY
| CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC) | 著者 | Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H. | 登録日 | 2021-08-28 | 公開日 | 2022-06-08 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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6PIG
| V. cholerae TniQ-Cascade complex, closed conformation | 分子名称: | RNA (60-MER), TniQ monomer 1, TniQ monomer 2, ... | 著者 | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | 登録日 | 2019-06-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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6PIJ
| Target DNA-bound V. cholerae TniQ-Cascade complex, closed conformation | 分子名称: | Non-targeting strand ssDNA, Targeting strand ssDNA, TniQ monomer 2, ... | 著者 | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | 登録日 | 2019-06-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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6PIF
| V. cholerae TniQ-Cascade complex, open conformation | 分子名称: | Cas7, type I-F CRISPR-associated protein, TniQ monomer 1, ... | 著者 | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | 登録日 | 2019-06-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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4AL6
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4AL5
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4AL7
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4CMP
| Crystal structure of S. pyogenes Cas9 | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | 登録日 | 2014-01-16 | 公開日 | 2014-02-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation. Science, 343, 2014
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4CMQ
| Crystal structure of Mn-bound S.pyogenes Cas9 | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | 登録日 | 2014-01-17 | 公開日 | 2014-02-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation Science, 343, 2014
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7UFI
| VchTnsC AAA+ ATPase with DNA, single heptamer | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*TP*CP*CP*AP*GP*TP*AP*CP*AP*GP*CP*GP*CP*GP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*GP*CP*CP*GP*CP*GP*CP*TP*GP*TP*AP*CP*TP*GP*GP*AP*G)-3'), ... | 著者 | Fernandez, I.S, Sternberg, S.H. | 登録日 | 2022-03-22 | 公開日 | 2022-06-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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7UFM
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4OGC
| Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | 分子名称: | ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ... | 著者 | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | 登録日 | 2014-01-15 | 公開日 | 2014-02-12 | 最終更新日 | 2014-03-26 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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4OGE
| Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | 分子名称: | HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ... | 著者 | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | 登録日 | 2014-01-15 | 公開日 | 2014-02-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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