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6GJW
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BU of 6gjw by Molmil
Structure of XIAP-BIR1 domain in complex with an NF023 analog
分子名称: 4-[[3-[[3-[(4,8-disulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoylamino]phenyl]carbonylamino]naphthalene-1,5-disulfonate, E3 ubiquitin-protein ligase XIAP, ZINC ION
著者Sorrentino, L, Cossu, F, Malkoc, B, Zaffaroni, M, Milani, M, Mastrangelo, E.
登録日2018-05-17
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1.
Chemistryopen, 8, 2019
6QCI
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BU of 6qci by Molmil
Structure of XIAP-BIR1 V86E mutant
分子名称: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ...
著者Sorrentino, L, Cossu, F, Milani, M, Mastrangelo, E.
登録日2018-12-28
公開日2019-05-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1.
Chemistryopen, 8, 2019
5MIV
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BU of 5miv by Molmil
G307E variant of murine Apoptosis Inducing Factor in complex with NAD+
分子名称: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Sorrentino, L, Cossu, F, Aliverti, A, Milani, M, Mastrangelo, E.
登録日2016-11-29
公開日2017-07-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor.
Biochem. Biophys. Res. Commun., 490, 2017
5MIU
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BU of 5miu by Molmil
G307E variant of Murine Apoptosis Inducing Factor (oxidized state)
分子名称: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE
著者Sorrentino, L, Cossu, F, Milani, M, Aliverti, A, Mastrangelo, E.
登録日2016-11-29
公開日2017-07-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor.
Biochem. Biophys. Res. Commun., 490, 2017
7NK0
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BU of 7nk0 by Molmil
Structure of the BIR1 domain of cIAP2
分子名称: Baculoviral IAP repeat-containing protein 3, ZINC ION
著者Cossu, F, Milani, M, Mastrangelo, E, Mirdita, D.
登録日2021-02-17
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-kappa B pathway.
Comput Struct Biotechnol J, 19, 2021

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件を2024-07-17に公開中

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