4Z0C
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![BU of 4z0c by Molmil](/molmil-images/mine/4z0c) | Crystal structure of TLR13-ssRNA13 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-R(P*AP*CP*GP*GP*AP*AP*AP*GP*AP*CP*CP*CP*C)-3'), ... | 著者 | Song, W, Han, Z, Chai, J. | 登録日 | 2015-03-26 | 公開日 | 2015-10-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13 Nat.Struct.Mol.Biol., 22, 2015
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8A8E
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![BU of 8a8e by Molmil](/molmil-images/mine/8a8e) | PPSA C terminal octahedral structure | 分子名称: | Phosphoenolpyruvate synthase | 著者 | Song, W. | 登録日 | 2022-06-22 | 公開日 | 2023-07-05 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Survival strategies in the heat Lysine acetylation stabilizes the quaternary structure of a Mega-Dalton hyperthermophilic PEP-synthase To Be Published
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5HYX
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![BU of 5hyx by Molmil](/molmil-images/mine/5hyx) | Plant peptide hormone receptor RGFR1 in complex with RGF1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PTR-SER-ASN-PRO-GLY-HIS-HIS-PRO-HYP-ARG-HIS-ASN, ... | 著者 | Song, W, Han, Z, Chai, J. | 登録日 | 2016-02-02 | 公開日 | 2017-01-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | 主引用文献 | Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth Cell Res., 26, 2016
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5HZ3
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5HZ0
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5HZ1
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8CIE
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![BU of 8cie by Molmil](/molmil-images/mine/8cie) | Crystal structure of the human CDKL5 kinase domain with compound YL-354 | 分子名称: | 4-[[3,5-bis(fluoranyl)phenyl]carbonylamino]-~{N}-piperidin-4-yl-1~{H}-pyrazole-3-carboxamide, Cyclin-dependent kinase-like 5, SULFATE ION | 著者 | Richardson, W, Chen, X, Newman, J.A, Bakshi, S, Lakshminarayana, B, Brooke, L, Bullock, A.N. | 登録日 | 2023-02-09 | 公開日 | 2023-06-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. Acs Chem Neurosci, 14, 2023
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7XOZ
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![BU of 7xoz by Molmil](/molmil-images/mine/7xoz) | Crystal structure of RPPT-TIR | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | 著者 | Song, W, Jia, A, Huang, S, Chai, J. | 登録日 | 2022-05-02 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity. Science, 377, 2022
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6ACG
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6ACJ
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6ACK
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6ACD
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6ACC
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8HR6
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![BU of 8hr6 by Molmil](/molmil-images/mine/8hr6) | |
8HPE
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![BU of 8hpe by Molmil](/molmil-images/mine/8hpe) | Crystal structure of Leucine dehydrogenase | 分子名称: | GLYCEROL, Leucine dehydrogenase, SULFATE ION | 著者 | Li, X, Song, W. | 登録日 | 2022-12-12 | 公開日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | A Tri-Enzyme Cascade for Efficient Production of L-2-Aminobutyrate from L-Threonine. Chembiochem, 24, 2023
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7O2T
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![BU of 7o2t by Molmil](/molmil-images/mine/7o2t) | PqsR (MvfR) in complex with antagonist 61 | 分子名称: | 2-[4-[(2S)-3-(6-chloro-4-oxoquinazolin-3-yl)-2-hydroxypropoxy]phenyl]acetonitrile, LysR family transcriptional regulator | 著者 | Emsley, J, Richardson, W. | 登録日 | 2021-03-31 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | PqsR (MvfR) in complex with antagonist 61 To Be Published
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7O2U
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![BU of 7o2u by Molmil](/molmil-images/mine/7o2u) | PqsR (MvfR) in complex with antagonist 40 | 分子名称: | 2-[4-[(2S)-3-(6-chloranyl-4-oxidanylidene-quinazolin-3-yl)-2-oxidanyl-propoxy]phenoxy]ethanenitrile, LysR family transcriptional regulator | 著者 | Emsley, J, Richardson, W. | 登録日 | 2021-03-31 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | PqsR (MvfR) in complex with antagonist 40 To Be Published
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8HP4
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![BU of 8hp4 by Molmil](/molmil-images/mine/8hp4) | CtPDC complex | 分子名称: | MAGNESIUM ION, Pyruvate decarboxylase, THIAMINE DIPHOSPHATE | 著者 | Xu, H.H, Song, W. | 登録日 | 2022-12-11 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Protein engineering of pyruvate decarboxylase to remove the rate-limiting bottleneck in the cascade pathway of tyrosol synthesis To Be Published
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8HP2
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![BU of 8hp2 by Molmil](/molmil-images/mine/8hp2) | CtPDC | 分子名称: | Pyruvate decarboxylase | 著者 | Xu, H.H, Song, W. | 登録日 | 2022-12-11 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Protein engineering of pyruvate decarboxylase to remove the rate-limiting bottleneck in the cascade pathway of tyrosol synthesis To Be Published
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3N9I
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![BU of 3n9i by Molmil](/molmil-images/mine/3n9i) | Crystal structure of tryptophanyl-tRNA synthetase from Yersinia pestis CO92 | 分子名称: | CALCIUM ION, GLYCEROL, Tryptophanyl-tRNA synthetase | 著者 | Nocek, B, Maltseva, N, Papazisi, L, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-05-30 | 公開日 | 2010-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of tryptophanyl-tRNA synthetase from Yersinia pestis CO92 TO BE PUBLISHED
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3N2A
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![BU of 3n2a by Molmil](/molmil-images/mine/3n2a) | Crystal structure of bifunctional folylpolyglutamate synthase/dihydrofolate synthase from Yersinia pestis CO92 | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Bifunctional folylpolyglutamate synthase/dihydrofolate synthase, ... | 著者 | Nocek, B, Maltseva, N, Papazisi, L, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-05-17 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of bifunctional folylpolyglutamate synthase/dihydrofolate synthase from Yersinia pestis CO92 TO BE PUBLISHED
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4D09
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![BU of 4d09 by Molmil](/molmil-images/mine/4d09) | PDE2a catalytic domain in complex with a brain penetrant inhibitor | 分子名称: | CGMP-DEPENDENT 3', 5'-CYCLIC PHOSPHODIESTERASE, MAGNESIUM ION, ... | 著者 | Buijnsters, P, Andres, J.I, DeAngelis, M, Langlois, X, Rombouts, F, Sanderson, W, Tresadern, G, Trabanco, A, VanHoof, G, VanRoosbroeck, Y. | 登録日 | 2014-04-24 | 公開日 | 2014-08-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-Based Design of a Potent, Selective, and Brain Penetrating Pde2 Inhibitor with Demonstrated Target Engagement. Acs Med.Chem.Lett., 5, 2014
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9FGO
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![BU of 9fgo by Molmil](/molmil-images/mine/9fgo) | Crystal structure of Enterovirus 71 2A protease mutant C110A containing VP1-2A junction in the active site | 分子名称: | CHLORIDE ION, Polyprotein, ZINC ION | 著者 | Ni, X, Koekemoer, L, Williams, E.P, Wang, S, Wright, N.D, Godoy, A.S, Aschenbrenner, J.C, Balcomb, B.H, Lithgo, R.M, Marples, P.G, Fairhead, M, Thompson, W, Kirkegaard, K, Fearon, D, Walsh, M.A, von Delft, F. | 登録日 | 2024-05-24 | 公開日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Crystal structure of Enterovirus 71 2A protease mutant C110A containing VP1-2A junction in the active site To Be Published
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2M6M
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7GB3
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![BU of 7gb3 by Molmil](/molmil-images/mine/7gb3) | Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with DAV-CRI-3edb475e-6 (Mpro-x10172) | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, N-[(1S)-1-(3-chloro-5-fluorophenyl)ethyl]acetamide | 著者 | Fearon, D, Aimon, A, Aschenbrenner, J.C, Balcomb, B.H, Bertram, F.K.R, Brandao-Neto, J, Dias, A, Douangamath, A, Dunnett, L, Godoy, A.S, Gorrie-Stone, T.J, Koekemoer, L, Krojer, T, Lithgo, R.M, Lukacik, P, Marples, P.G, Mikolajek, H, Nelson, E, Owen, C.D, Powell, A.J, Rangel, V.L, Skyner, R, Strain-Damerell, C.M, Thompson, W, Tomlinson, C.W.E, Wild, C, Walsh, M.A, von Delft, F. | 登録日 | 2023-08-11 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.379 Å) | 主引用文献 | Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science, 382, 2023
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