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1MYJ
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DISTAL POLARITY IN LIGAND BINDING TO MYOGLOBIN: STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A THREONINE68(E11) MUTANT
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Smerdon, S.J, Oldfield, T.J, Wilkinson, A.J, Dauter, Z, Petratos, K, Wilson, K.S.
登録日1992-02-27
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Distal pocket polarity in ligand binding to myoglobin: structural and functional characterization of a threonine68(E11) mutant.
Biochemistry, 30, 1991
1PMB
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THE DETERMINATION OF THE CRYSTAL STRUCTURE OF RECOMBINANT PIG MYOGLOBIN BY MOLECULAR REPLACEMENT AND ITS REFINEMENT
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Smerdon, S.J, Oldfield, T.J, Dodson, E.J, Dodson, G.G, Hubbard, R.E, Wilkinson, A.J.
登録日1989-11-27
公開日1990-01-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Determination of the crystal structure of recombinant pig myoglobin by molecular replacement and its refinement.
Acta Crystallogr.,Sect.B, 46, 1990
3HVT
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STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER
分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66)
著者Steitz, T.A, Smerdon, S.J, Jaeger, J, Wang, J, Kohlstaedt, L.A, Chirino, A.J, Friedman, J.M, Rice, P.A.
登録日1994-07-25
公開日1994-10-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
Proc.Natl.Acad.Sci.Usa, 91, 1994
1MYG
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BU of 1myg by Molmil
HIGH RESOLUTION X-RAY STRUCTURES OF PIG METMYOGLOBIN AND TWO CD3 MUTANTS MB(LYS45-> ARG) AND MB(LYS45-> SER)
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Smerdon, S.J, Oldfield, T.J, Wilkinson, A.J, Dauter, Z, Petratos, K, Wilson, K.S.
登録日1992-02-27
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献High-resolution X-ray structures of pig metmyoglobin and two CD3 mutants: Mb(Lys45----Arg) and Mb(Lys45----Ser).
Biochemistry, 31, 1992
2XFV
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BU of 2xfv by Molmil
Structure of the amino-terminal domain from the cell-cycle regulator Swi6
分子名称: ACETATE ION, CACODYLATE ION, CALCIUM ION, ...
著者Smerdon, S.J, Goldstone, D.C, Taylor, I.A.
登録日2010-05-27
公開日2010-06-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the Amino-Terminal Domain from the Cell-Cycle Regulator Swi6S
Proteins, 78, 2010
1MYH
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BU of 1myh by Molmil
HIGH RESOLUTION X-RAY STRUCTURES OF PIG METMYOGLOBIN AND TWO CD3 MUTANTS MB(LYS45-> ARG) AND MB(LYS45-> SER)
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Smerdon, S.J, Oldfield, T.J, Wilkinson, A.J, Dauter, Z, Petratos, K, Wilson, K.S.
登録日1992-02-27
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution X-ray structures of pig metmyoglobin and two CD3 mutants: Mb(Lys45----Arg) and Mb(Lys45----Ser).
Biochemistry, 31, 1992
4PSF
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BU of 4psf by Molmil
PIH1D1 N-terminal domain
分子名称: PIH1 domain-containing protein 1
著者Smerdon, S.J, Boulton, S.J, Stach, L, Flower, T.G, Horejsi, Z.
登録日2014-03-07
公開日2014-04-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.578 Å)
主引用文献Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex.
Cell Rep, 7, 2014
4PSI
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PIH1D1/phospho-Tel2 complex
分子名称: PIH1 domain-containing protein 1, Telomere length regulation protein TEL2 homolog
著者Smerdon, S.J, Boulton, S.J, Stach, L, Flower, T.G, Horejsi, Z.
登録日2014-03-07
公開日2014-04-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex.
Cell Rep, 7, 2014
1MYI
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BU of 1myi by Molmil
HIGH RESOLUTION X-RAY STRUCTURES OF PIG METMYOGLOBIN AND TWO CD3 MUTANTS MB(LYS45-> ARG) AND MB(LYS45-> SER)
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Smerdon, S.J, Oldfield, T.J, Wilkinson, A.J, Dauter, Z, Petratos, K, Wilson, K.S.
登録日1992-02-27
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High-resolution X-ray structures of pig metmyoglobin and two CD3 mutants: Mb(Lys45----Arg) and Mb(Lys45----Ser).
Biochemistry, 31, 1992
2KFU
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BU of 2kfu by Molmil
PknB-phosphorylated Rv1827
分子名称: Rv1827 pThr 22
著者Smerdon, S.J, Nott, T.J, Kelly, G.
登録日2009-02-27
公開日2009-06-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis.
Sci.Signal., 2, 2009
4QBL
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BU of 4qbl by Molmil
VRR_NUC domain protein
分子名称: MAGNESIUM ION, VRR-NUC
著者Smerdon, S.J, Pennell, S, Li, J.
登録日2014-05-08
公開日2014-09-10
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain.
Cell Rep, 8, 2014
4QBN
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VRR_NUC domain
分子名称: Nuclease, SULFATE ION
著者Smerdon, S.J, Pennell, S, Li, J.
登録日2014-05-08
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain.
Cell Rep, 8, 2014
4QBO
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VRR_NUC domain
分子名称: MAGNESIUM ION, Nuclease
著者Smerdon, S.J, Pennell, S, Li, J.
登録日2014-05-08
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain.
Cell Rep, 8, 2014
1QJA
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BU of 1qja by Molmil
14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2)
分子名称: 14-3-3 PROTEIN ZETA, PHOSPHOPEPTIDE
著者Rittinger, K, Budman, J, Xu, J, Volinia, S, Cantley, L.C, Smerdon, S.J, Gamblin, S.J, Yaffe, M.B.
登録日1999-06-23
公開日1999-09-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding
Mol.Cell, 4, 1999
2AZM
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BU of 2azm by Molmil
Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX
分子名称: GAMMA-H2AX HISTONE, Mediator of DNA damage checkpoint protein 1
著者Clapperton, J.A, Stucki, M, Mohammad, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J.
登録日2005-09-12
公開日2006-01-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
Cell(Cambridge,Mass.), 123, 2005
3KT9
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BU of 3kt9 by Molmil
Aprataxin FHA Domain
分子名称: Aprataxin
著者Cherry, A.L, Smerdon, S.J.
登録日2009-11-24
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.
Nucleic Acids Res., 38, 2010
5LHU
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BU of 5lhu by Molmil
ATP Phosphoribosyltransferase from Mycobacterium tuberculosis in complex with the allosteric inhibitor L-Histidine
分子名称: ATP phosphoribosyltransferase, GLYCEROL, HISTIDINE, ...
著者de Chiara, C, Pisco, J.P, de Carvalho, L.P, Smerdon, S.J, Walker, P.A, Ogrodowicz, R.
登録日2016-07-12
公開日2017-06-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Uncoupling conformational states from activity in an allosteric enzyme.
Nat Commun, 8, 2017
1YCB
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BU of 1ycb by Molmil
DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R.
登録日1993-08-10
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
1YCA
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BU of 1yca by Molmil
DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R.
登録日1993-08-10
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
1E96
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BU of 1e96 by Molmil
Structure of the Rac/p67phox complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ...
著者Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K.
登録日2000-10-10
公開日2000-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the TPR domain of p67phox in complex with Rac.GTP.
Mol.Cell, 6, 2000
5IQP
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14-3-3 PROTEIN TAU ISOFORM
分子名称: 14-3-3 protein theta, SULFATE ION
著者Xiao, B, Smerdon, S.J, Gamblin, S.J.
登録日2016-03-11
公開日2016-03-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways
Nature, 376, 1995
1AM4
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COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS)
分子名称: CDC42HS, MAGNESIUM ION, P50-RHOGAP, ...
著者Rittinger, K, Walker, P, Gamblin, S.J, Smerdon, S.J.
登録日1997-06-22
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
Nature, 388, 1997
5LHT
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BU of 5lht by Molmil
ATP Phosphoribosyltransferase from Mycobacterium tuberculosis in complex with the allosteric activator 3-(2-Thienyl)-L-alanine
分子名称: ATP phosphoribosyltransferase, BETA(2-THIENYL)ALANINE, GLYCEROL, ...
著者de Chiara, C, Pisco, J.P, de Carvalho, L.P, Smerdon, S.J, Walker, P.A, Ogrodowicz, R.
登録日2016-07-12
公開日2017-07-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.0601 Å)
主引用文献Uncoupling conformational states from activity in an allosteric enzyme.
Nat Commun, 8, 2017
2BF0
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crystal structure of the rpr of pcf11
分子名称: CALCIUM ION, PCF11
著者Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A.
登録日2004-12-02
公開日2005-01-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd.
Nat.Struct.Mol.Biol., 12, 2005
4JIZ
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BU of 4jiz by Molmil
Human Mob1-phosphopeptide complex
分子名称: MOB kinase activator 1A, ZINC ION, phosphopeptide
著者Stach, L, Ogrodowicz, R.W, Rock, J.M, Lim, D, Yaffe, M.B, Amon, A, Smerdon, S.J.
登録日2013-03-07
公開日2013-04-17
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes.
Science, 340, 2013

 

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