3J4J
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![BU of 3j4j by Molmil](/molmil-images/mine/3j4j) | Model of full-length T. thermophilus Translation Initiation Factor 2 refined against its cryo-EM density from a 30S Initiation Complex map | 分子名称: | Translation initiation factor IF-2 | 著者 | Simonetti, A, Marzi, S, Billas, I.M.L, Tsai, A, Fabbretti, A, Myasnikov, A, Roblin, P, Vaiana, A.C, Hazemann, I, Eiler, D, Steitz, T.A, Puglisi, J.D, Gualerzi, C.O, Klaholz, B.P. | 登録日 | 2013-08-26 | 公開日 | 2013-09-25 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (11.5 Å) | 主引用文献 | Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor. Proc.Natl.Acad.Sci.USA, 110, 2013
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5K1H
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![BU of 5k1h by Molmil](/molmil-images/mine/5k1h) | eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation. | 分子名称: | Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail | 著者 | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | 登録日 | 2016-05-18 | 公開日 | 2016-07-13 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
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5K0Y
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![BU of 5k0y by Molmil](/molmil-images/mine/5k0y) | m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | 著者 | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | 登録日 | 2016-05-17 | 公開日 | 2016-07-13 | 最終更新日 | 2018-04-18 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
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4B3X
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![BU of 4b3x by Molmil](/molmil-images/mine/4b3x) | Bacterial translation initiation factor IF2 (1-363), apo form | 分子名称: | GLYCEROL, TRANSLATION INITIATION FACTOR IF-2 | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | 登録日 | 2012-07-26 | 公開日 | 2013-05-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms Acta Crystallogr.,Sect.D, 69, 2013
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4B48
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![BU of 4b48 by Molmil](/molmil-images/mine/4b48) | Bacterial translation initiation factor IF2 (1-363), complex with GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRANSLATION INITIATION FACTOR IF-2 | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | 登録日 | 2012-07-27 | 公開日 | 2013-05-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms Acta Crystallogr.,Sect.D, 69, 2013
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4B43
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![BU of 4b43 by Molmil](/molmil-images/mine/4b43) | Bacterial translation initiation factor IF2 (1-363), apo form, double mutant K86L H130A | 分子名称: | GLYCEROL, IODIDE ION, MAGNESIUM ION, ... | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | 登録日 | 2012-07-27 | 公開日 | 2013-09-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.937 Å) | 主引用文献 | Molecular Basis of GTP Hydrolysis by Bacterial Translation Initiation Factor If2 To be Published
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4B44
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4B47
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![BU of 4b47 by Molmil](/molmil-images/mine/4b47) | Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH6.5 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSLATION INITIATION FACTOR IF-2 | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | 登録日 | 2012-07-27 | 公開日 | 2013-05-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms Acta Crystallogr.,Sect.D, 69, 2013
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6YAN
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![BU of 6yan by Molmil](/molmil-images/mine/6yan) | Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6YAM
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![BU of 6yam by Molmil](/molmil-images/mine/6yam) | Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6YAL
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![BU of 6yal by Molmil](/molmil-images/mine/6yal) | Mammalian 48S late-stage initiation complex with beta-globin mRNA | 分子名称: | 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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5ND9
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![BU of 5nd9 by Molmil](/molmil-images/mine/5nd9) | Hibernating ribosome from Staphylococcus aureus (Rotated state) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y. | 登録日 | 2017-03-07 | 公開日 | 2017-06-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF. EMBO J., 36, 2017
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5ND8
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![BU of 5nd8 by Molmil](/molmil-images/mine/5nd8) | Hibernating ribosome from Staphylococcus aureus (Unrotated state) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y. | 登録日 | 2017-03-07 | 公開日 | 2017-06-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF. EMBO J., 36, 2017
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6GQ1
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![BU of 6gq1 by Molmil](/molmil-images/mine/6gq1) | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Pellegrino, S, Demeshkina, N, Mancera-Martinez, E, Melnikov, S, Simonetti, A, Myasnikov, A, Yusupov, M, Yusupova, G, Hashem, Y. | 登録日 | 2018-06-07 | 公開日 | 2018-07-11 | 最終更新日 | 2018-08-08 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
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5OPT
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![BU of 5opt by Molmil](/molmil-images/mine/5opt) | Structure of KSRP in context of Trypanosoma cruzi 40S | 分子名称: | 18S rRNA, 40S ribosomal protein S10, putative, ... | 著者 | Brito Querido, J, Mancera-Martinez, E, Vicens, Q, Bochler, A, Chicher, J, Simonetti, A, Hashem, Y. | 登録日 | 2017-08-10 | 公開日 | 2017-11-15 | 最終更新日 | 2017-12-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein. Structure, 25, 2017
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5OSG
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![BU of 5osg by Molmil](/molmil-images/mine/5osg) | Structure of KSRP in context of Leishmania donovani 80S | 分子名称: | 18S rRNA, 40S ribosomal protein S6, RNA binding protein, ... | 著者 | Brito Querido, J, Mancera-Martinez, E, Vicens, Q, Bochler, A, Chicher, J, Simonetti, A, Hashem, Y. | 登録日 | 2017-08-17 | 公開日 | 2017-11-15 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein. Structure, 25, 2017
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7A01
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![BU of 7a01 by Molmil](/molmil-images/mine/7a01) | The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism | 分子名称: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ... | 著者 | Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T. | 登録日 | 2020-08-05 | 公開日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism. Cell Rep, 33, 2020
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6ZVK
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![BU of 6zvk by Molmil](/molmil-images/mine/6zvk) | The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism | 分子名称: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ... | 著者 | Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T. | 登録日 | 2020-07-24 | 公開日 | 2020-12-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism. Cell Rep, 33, 2020
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8PUT
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![BU of 8put by Molmil](/molmil-images/mine/8put) | IF5A in complex with Deoxyhypusine synthase | 分子名称: | DI(HYDROXYETHYL)ETHER, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable deoxyhypusine synthase, ... | 著者 | Ennifar, E, D'agostino, M. | 登録日 | 2023-07-17 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of archaeal IF5A-DHS complex reveals insights into the hypusination mechanism. Structure, 32, 2024
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4KJZ
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5NKO
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![BU of 5nko by Molmil](/molmil-images/mine/5nko) | Solution structure of the C-terminal domain of S. aureus Hibernating Promoting Factor (CTD-SaHPF) | 分子名称: | Ribosome hibernation promotion factor | 著者 | Usachev, K.S, Khusainov, I.S, Ayupov, R.K, Validov, S.Z, Kieffer, B, Yusupov, M.M. | 登録日 | 2017-03-31 | 公開日 | 2017-07-05 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF. EMBO J., 36, 2017
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6GQB
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![BU of 6gqb by Molmil](/molmil-images/mine/6gqb) | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. | 登録日 | 2018-06-07 | 公開日 | 2018-07-11 | 最終更新日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
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6GQV
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![BU of 6gqv by Molmil](/molmil-images/mine/6gqv) | Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. | 登録日 | 2018-06-08 | 公開日 | 2018-07-11 | 最終更新日 | 2018-08-08 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
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7ASK
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![BU of 7ask by Molmil](/molmil-images/mine/7ask) | 43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase bound with ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kDDX60 | 著者 | Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. | 登録日 | 2020-10-27 | 公開日 | 2021-04-14 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
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7ASE
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![BU of 7ase by Molmil](/molmil-images/mine/7ase) | 43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase | 分子名称: | 18S, 40S ribosomal protein S10, putative, ... | 著者 | Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. | 登録日 | 2020-10-27 | 公開日 | 2021-04-14 | 最終更新日 | 2021-04-21 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
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