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Vegfr2 in complex with a novel 4-amino-furo[2,3-d]pyrimidine
分子名称:	N-{4-[4-AMINO-6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-5-YL]PHENYL}-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA, Vascular endothelial growth factor receptor 2
著者	Miyazaki, Y, Matsunaga, S, Tang, J, Maeda, Y, Nakano, M, Philippe, R.J, Shibahara, M, Liu, W, Sato, H, Wang, L, Nolte, R.T.
登録日	2005-02-18
公開日	2005-08-23
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.71 Å)
主引用文献	Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors Bioorg.Med.Chem.Lett., 15, 2005

Crystal structure of Vegfr2 with a benzimidazole-urea inhibitor
分子名称:	METHYL (5-{4-[({[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-1H-BENZIMIDAZOL-2-YL)CARBAMATE, SULFATE ION, Vascular endothelial growth factor receptor 2
著者	Nolte, R.T, Wang, L.
登録日	2007-01-09
公開日	2007-09-18
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Discovery of Novel Benzimidazoles as Potent Inhibitors of TIE-2 and VEGFR-2 Tyrosine Kinase Receptors. J.Med.Chem., 50, 2007