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7R3X
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BU of 7r3x by Molmil
The crystal structure of the L439V variant of Pol2CORE in complex with DNA and an incoming nucleotide
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ACETATE ION, CALCIUM ION, ...
著者Barbari, S.R, Beach, A.K, Markgren, J.G, Parkash, V, Johansson, E, Shcherbakova, P.V.
登録日2022-02-08
公開日2022-07-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ε variants at low dNTP levels.
Nucleic Acids Res., 50, 2022
7R3Y
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BU of 7r3y by Molmil
The crystal structure of the V426L variant of Pol2CORE in complex with DNA and an incoming nucleotide
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA Primer, ...
著者Barbari, S.R, Beach, A.K, Markgren, J.G, Parkash, V, Johansson, E, Shcherbakova, P.V.
登録日2022-02-08
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ε variants at low dNTP levels.
Nucleic Acids Res., 50, 2022
6I8A
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BU of 6i8a by Molmil
The crystal structure of the Pol2 catalytic domain of DNA polymerase epsilon carrying a P301R substitution.
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2018-11-19
公開日2019-01-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.652 Å)
主引用文献Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon.
Nat Commun, 10, 2019
6FWK
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BU of 6fwk by Molmil
The crystal structure of Pol2CORE-M644G in complex with DNA and an incoming nucleotide
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*TP*AP*AP*CP*CP*GP*CP*GP*TP*TP*(DOC))-3'), ...
著者Parkash, V, Johansson, E.
登録日2018-03-06
公開日2019-01-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon.
Nat Commun, 10, 2019
6G0A
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BU of 6g0a by Molmil
The crystal structure of the Pol2 catalytic domain of DNA polymerase epsilon carrying a P301R substitution.
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*TP*AP*AP*CP*CP*GP*CP*GP*TP*TP*DC)-3'), ...
著者Parkash, V, Johansson, E.
登録日2018-03-16
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon.
Nat Commun, 10, 2019

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