6NT7
 
 | | Cryo-EM structure of full-length chicken STING in the cGAMP-bound dimeric state | | 分子名称: | Stimulator of interferon genes protein, cGAMP | | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | | 登録日 | 2019-01-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 567, 2019
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6NT8
 | | Cryo-EM structure of full-length chicken STING in the cGAMP-bound tetrameric state | | 分子名称: | Stimulator of interferon genes protein, cGAMP | | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | | 登録日 | 2019-01-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 567, 2019
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4EQ8
 | | Crystal structure of PA1844 from Pseudomonas aeruginosa PAO1 | | 分子名称: | GLYCEROL, Putative uncharacterized protein | | 著者 | Shang, G, Li, N, Zhang, J, Lu, D, Yu, Q, Zhao, Y, Liu, X, Xu, S, Gu, L. | | 登録日 | 2012-04-18 | | 公開日 | 2012-09-12 | | 最終更新日 | 2013-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.392 Å) | | 主引用文献 | Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function.
Biochem.J., 448, 2012
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4EQA
 | | Crystal structure of PA1844 in complex with PA1845 from Pseudomonas aeruginosa PAO1 | | 分子名称: | Putative uncharacterized protein | | 著者 | Shang, G, Li, N, Zhang, J, Lu, D, Yu, Q, Zhao, Y, Liu, X, Xu, S, Gu, L. | | 登録日 | 2012-04-18 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function.
Biochem.J., 448, 2012
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5V6H
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5V6E
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5V6T
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5V6B
 | | Crystal structure of GIPC1 | | 分子名称: | PDZ domain-containing protein GIPC1 | | 著者 | Shang, G, Zhang, X. | | 登録日 | 2017-03-16 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife, 6, 2017
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5V6R
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8HB2
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8HBB
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8HAZ
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6NT5
 | | Cryo-EM structure of full-length human STING in the apo state | | 分子名称: | Stimulator of interferon protein | | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | | 登録日 | 2019-01-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 567, 2019
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6NT6
 | | Cryo-EM structure of full-length chicken STING in the apo state | | 分子名称: | Stimulator of interferon genes protein | | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | | 登録日 | 2019-01-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 567, 2019
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6NT9
 | | Cryo-EM structure of the complex between human TBK1 and chicken STING | | 分子名称: | Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein | | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | | 登録日 | 2019-01-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of STING binding with and phosphorylation by TBK1.
Nature, 567, 2019
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4F5W
 | | Crystal structure of ligand free human STING CTD | | 分子名称: | CALCIUM ION, Transmembrane protein 173 | | 著者 | Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. | | 登録日 | 2012-05-13 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Nat.Struct.Mol.Biol., 19, 2012
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4F5Y
 | | Crystal structure of human STING CTD complex with C-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 | | 著者 | Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. | | 登録日 | 2012-05-13 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.396 Å) | | 主引用文献 | Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Nat.Struct.Mol.Biol., 19, 2012
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7SII
 | | Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | | 分子名称: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | | 著者 | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | | 登録日 | 2021-10-14 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Activation of STING by targeting a pocket in the transmembrane domain.
Nature, 604, 2022
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7M0R
 | | Cryo-EM structure of the Sema3A/PlexinA4/Neuropilin 1 complex | | 分子名称: | CALCIUM ION, Neuropilin-1, Plexin-A4, ... | | 著者 | Lu, D, Shang, G, He, X, Bai, X, Zhang, X. | | 登録日 | 2021-03-11 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-06-09 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Architecture of the Sema3A/PlexinA4/Neuropilin tripartite complex.
Nat Commun, 12, 2021
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5HHA
 | | Structure of PvdO from Pseudomonas aeruginosa | | 分子名称: | CALCIUM ION, PvdO | | 著者 | Bai, G, Yuan, Z, Shang, G, Xia, H, Gu, L. | | 登録日 | 2016-01-10 | | 公開日 | 2017-01-18 | | 最終更新日 | 2017-01-25 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Crystal structure of Chromophore maturation protein from Pseudomonas aeruginosa
To Be Published
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6VXK
 | | Cryo-EM Structure of the full-length A39R/PlexinC1 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-C1, Semaphorin-like protein 139 | | 著者 | Kuo, Y.-C, Chen, H, Shang, G, Uchikawa, E, Tian, H, Bai, X, Zhang, X. | | 登録日 | 2020-02-22 | | 公開日 | 2020-04-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation.
Nat Commun, 11, 2020
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6J22
 | | Crystal structure of Bi-functional enzyme | | 分子名称: | Histidine biosynthesis bifunctional protein HisIE | | 著者 | Zhang, H, Shang, G, Wang, Y. | | 登録日 | 2018-12-30 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analysis of Shigella flexneri bi-functional enzyme HisIE in histidine biosynthesis.
Biochem.Biophys.Res.Commun., 516, 2019
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6J2L
 | | Crystal structure of Bi-functional enzyme | | 分子名称: | Histidine biosynthesis bifunctional protein HisIE, MAGNESIUM ION, ZINC ION | | 著者 | Zhang, H, Shang, G, Wang, Y. | | 登録日 | 2019-01-01 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structural analysis of Shigella flexneri bi-functional enzyme HisIE in histidine biosynthesis.
Biochem.Biophys.Res.Commun., 516, 2019
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6N3H
 | | Crystal structure of Kelch domain of the human NS1 binding protein | | 分子名称: | Influenza virus NS1A-binding protein | | 著者 | Zhang, K, Shang, G, Padavannil, A, Fontoura, B.M.A, Chook, Y.M. | | 登録日 | 2018-11-15 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6N34
 | | Crystal structure of the BTB domain of Human NS1-BP | | 分子名称: | Influenza virus NS1A-binding protein | | 著者 | Zhang, K, Shang, G, Padavannil, A, Fontoura, B, Chook, Y.M. | | 登録日 | 2018-11-14 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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