1GSN
 
 | | HUMAN GLUTATHIONE REDUCTASE MODIFIED BY DINITROSOGLUTATHIONE | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GLUTATHIONE REDUCTASE, ... | | 著者 | Becker, K, Savvides, S.N, Keese, M, Schirmer, R.H, Karplus, P.A. | | 登録日 | 1998-02-21 | | 公開日 | 1998-05-27 | | 最終更新日 | 2011-12-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers.
Nat.Struct.Biol., 5, 1998
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1ALG
 | | SOLUTION STRUCTURE OF AN HGR INHIBITOR, NMR, 10 STRUCTURES | | 分子名称: | P11 | | 著者 | Schott, M.K, Nordhoff, A, Becker, K, Kalbitzer, H.R, Schirmer, R.H. | | 登録日 | 1997-06-03 | | 公開日 | 1997-10-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Denaturation and reactivation of dimeric human glutathione reductase--an assay for folding inhibitors.
Eur.J.Biochem., 245, 1997
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3SQP
 | | Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity | | 分子名称: | 5-methylphenazin-1(5H)-one, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Fritz-Wolf, K, Schirmer, R.H, Koenig, I, Goebel, U. | | 登録日 | 2011-07-06 | | 公開日 | 2011-09-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue.
Redox Rep., 16, 2011
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1ONF
 | | Crystal structure of Plasmodium falciparum Glutathione reductase | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase | | 著者 | Sarma, G.N, Savvides, S.N, Becker, K, Schirmer, M, Schirmer, R.H, Karplus, P.A. | | 登録日 | 2003-02-27 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Glutathione reductase of the malarial parasite Plasmodium falciparum: Crystal structure and inhibitor development
J.Mol.Biol., 328, 2003
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1XWA
 | | Drospohila thioredoxin, oxidized, P41212 | | 分子名称: | CADMIUM ION, CHLORIDE ION, thioredoxin | | 著者 | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | | 登録日 | 2004-10-29 | | 公開日 | 2004-11-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster
J.Mol.Biol., 345, 2005
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1XW9
 | | Drosophila thioredoxin, oxidized, P21 | | 分子名称: | thioredoxin | | 著者 | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | | 登録日 | 2004-10-29 | | 公開日 | 2004-11-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster
J.Mol.Biol., 345, 2005
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1XWB
 | | Drospohila thioredoxin, oxidized, P42212 | | 分子名称: | CADMIUM ION, thioredoxin | | 著者 | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | | 登録日 | 2004-10-29 | | 公開日 | 2004-11-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster
J.Mol.Biol., 345, 2005
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1XWC
 | | Drosophila thioredoxin, reduced, P6522 | | 分子名称: | thioredoxin | | 著者 | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | | 登録日 | 2004-10-29 | | 公開日 | 2004-11-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster
J.Mol.Biol., 345, 2005
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1K4Q
 | | Human Glutathione Reductase Inactivated by Peroxynitrite | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Glutathione Reductase | | 著者 | Savvides, S.N, Scheiwein, M, Boehme, C.C, Arteel, G.E, Karplus, P.A, Becker, K, Schirmer, R.H. | | 登録日 | 2001-10-08 | | 公開日 | 2002-01-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the antioxidant enzyme glutathione reductase inactivated by peroxynitrite.
J.Biol.Chem., 277, 2002
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1OKT
 | | X-ray Structure of Glutathione S-Transferase from the Malarial Parasite Plasmodium falciparum | | 分子名称: | FORMIC ACID, GLUTATHIONE S-TRANSFERASE | | 著者 | Fritz-Wolf, K, Becker, A, Rahlfs, s, Harwaldt, P, Schirmer, R.H, Kabsch, W, Becker, K. | | 登録日 | 2003-07-29 | | 公開日 | 2003-11-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-Ray Structure of Glutathione S-Transferase from the Malarial Parasite Plasmodium Falciparum
Proc.Natl.Acad.Sci.USA, 100, 2003
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1DNC
 | | HUMAN GLUTATHIONE REDUCTASE MODIFIED BY DIGLUTATHIONE-DINITROSO-IRON | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GLUTATHIONE REDUCTASE, ... | | 著者 | Becker, K, Savvides, S.N, Keese, M, Schirmer, R.H, Karplus, P.A. | | 登録日 | 1998-02-20 | | 公開日 | 1998-05-27 | | 最終更新日 | 2011-12-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers.
Nat.Struct.Biol., 5, 1998
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1GRA
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1GRF
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3GRS
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1GRT
 | | HUMAN GLUTATHIONE REDUCTASE A34E/R37W MUTANT | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE | | 著者 | Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F. | | 登録日 | 1996-12-17 | | 公開日 | 1997-06-16 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
Biochemistry, 36, 1997
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5GRT
 | | HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, GLUTATHIONYLSPERMIDINE COMPLEX | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, GLUTATHIONYLSPERMIDINE DISULFIDE | | 著者 | Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F. | | 登録日 | 1997-02-12 | | 公開日 | 1997-08-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
Biochemistry, 36, 1997
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3GRT
 | | HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, OXIDIZED TRYPANOTHIONE COMPLEX | | 分子名称: | 2-AMINO-4-[4-(4-AMINO-4-CARBOXY-BUTYRYLAMINO)-5,8,19,22-TETRAOXO-1,2-DITHIA-6,9,13,18,21-PENTAAZA-CYCLOTETRACOS-23-YLCARBAMOYL]-BUTYRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE | | 著者 | Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F. | | 登録日 | 1997-02-12 | | 公開日 | 1997-08-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
Biochemistry, 36, 1997
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3ADK
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2GRT
 | | HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, OXIDIZED GLUTATHIONE COMPLEX | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, OXIDIZED GLUTATHIONE DISULFIDE | | 著者 | Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F. | | 登録日 | 1997-02-12 | | 公開日 | 1997-08-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
Biochemistry, 36, 1997
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1GRB
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1GRE
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1GRG
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4GRT
 | | HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, MIXED DISULFIDE BETWEEN TRYPANOTHIONE AND THE ENZYME | | 分子名称: | BIS(GAMMA-GLUTAMYL-CYSTEINYL-GLYCINYL)SPERMIDINE, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE | | 著者 | Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F. | | 登録日 | 1997-02-12 | | 公開日 | 1997-08-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
Biochemistry, 36, 1997
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1GRH
 | | INHIBITION OF HUMAN GLUTATHIONE REDUCTASE BY THE NITROSOUREA DRUGS 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA AND 1-(2-CHLOROETHYL)-3-(2-HYDROXYETHYL)-1-NITROSOUREA | | 分子名称: | ETHANOL, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, ... | | 著者 | Karplus, P.A, Schulz, G.E. | | 登録日 | 1992-12-15 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea. A crystallographic analysis.
Eur.J.Biochem., 171, 1988
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2GH5
 | | Crystal Structure of human Glutathione Reductase complexed with a Fluoro-Analogue of the Menadione Derivative M5 | | 分子名称: | 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Fritz-Wolf, K, Winzer, A, Bauer, H, Schirmer, H, Davioud-Charvet, E. | | 登録日 | 2006-03-25 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme
J.Am.Chem.Soc., 128, 2006
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