3LQV
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3LRU
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5HT2
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![BU of 5ht2 by Molmil](/molmil-images/mine/5ht2) | Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with 1-N6-etheno-adenine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA, ... | 著者 | Schellenberg, M.J, Vilas, C.K, Williams, R.S. | 登録日 | 2016-01-26 | 公開日 | 2016-04-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016
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5INP
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5INO
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5INN
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![BU of 5inn by Molmil](/molmil-images/mine/5inn) | Mouse Tdp2 D358N protein, apo state with increased disorder amongst variable DNA-binding grasp conformations | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Schellenberg, M.J, Appel, C.D, Williams, R.S. | 登録日 | 2016-03-07 | 公開日 | 2016-04-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016
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5TVQ
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2F9J
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5TVP
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2F9D
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![BU of 2f9d by Molmil](/molmil-images/mine/2f9d) | 2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of SF3b155 | 分子名称: | Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1 | 著者 | Schellenberg, M.J, Edwards, R.A, Ritchie, D.B, Glover, J.N.M, Macmillan, A.M. | 登録日 | 2005-12-05 | 公開日 | 2006-01-24 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a core spliceosomal protein interface Proc.Natl.Acad.Sci.Usa, 103, 2006
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5INK
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5INM
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5INL
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![BU of 5inl by Molmil](/molmil-images/mine/5inl) | Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with deoxyadenosine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*AP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ... | 著者 | Schellenberg, M.J, Vilas, C.K, Williams, R.S. | 登録日 | 2016-03-07 | 公開日 | 2016-04-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | 主引用文献 | Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016
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5INQ
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4GZ1
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4GYZ
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![BU of 4gyz by Molmil](/molmil-images/mine/4gyz) | Mus Musculus Tdp2 Bound to dAMP and Mg2+ | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Schellenberg, M.J, Williams, R.S. | 登録日 | 2012-09-05 | 公開日 | 2012-10-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.556 Å) | 主引用文献 | Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2. Nat.Struct.Mol.Biol., 19, 2012
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4GZ0
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4GZ2
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![BU of 4gz2 by Molmil](/molmil-images/mine/4gz2) | Mus Musculus Tdp2 excluded ssDNA complex | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), FORMIC ACID, MAGNESIUM ION, ... | 著者 | Schellenberg, M.J, Williams, R.S. | 登録日 | 2012-09-05 | 公開日 | 2012-10-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2. Nat.Struct.Mol.Biol., 19, 2012
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6Q00
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![BU of 6q00 by Molmil](/molmil-images/mine/6q00) | TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1 | 分子名称: | POTASSIUM ION, Tyrosyl-DNA phosphodiesterase 2, Ubiquitin | 著者 | Schellenberg, M.J, Krahn, J.M, Williams, R.S. | 登録日 | 2019-08-01 | 公開日 | 2020-04-29 | 最終更新日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | 主引用文献 | Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2. Nucleic Acids Res., 48, 2020
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6Q01
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![BU of 6q01 by Molmil](/molmil-images/mine/6q01) | TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 2 | 分子名称: | 1,2-ETHANEDIOL, BENZOIC ACID, MAGNESIUM ION, ... | 著者 | Schellenberg, M.J, Krahn, J.M, Williams, R.S. | 登録日 | 2019-08-01 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (0.851 Å) | 主引用文献 | Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2. Nucleic Acids Res., 48, 2020
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4JK8
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![BU of 4jk8 by Molmil](/molmil-images/mine/4jk8) | Open and closed forms of R1865A human PRP8 RNase H-like domain with bound Mg ion | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
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4JKE
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![BU of 4jke by Molmil](/molmil-images/mine/4jke) | Open and closed forms of T1789P human PRP8 RNase H-like domain with bound Mg ion | 分子名称: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
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4JKF
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![BU of 4jkf by Molmil](/molmil-images/mine/4jkf) | Open and closed forms of T1791P+R1865A human PRP8 RNase H-like domain with bound Mg ion | 分子名称: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
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4JKA
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![BU of 4jka by Molmil](/molmil-images/mine/4jka) | Open and closed forms of R1865A human PRP8 RNase H-like domain with bound Co ion | 分子名称: | CHLORIDE ION, COBALT (II) ION, Pre-mRNA-processing-splicing factor 8 | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
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4JKG
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![BU of 4jkg by Molmil](/molmil-images/mine/4jkg) | Open and closed forms of mixed T1789P+R1865A and R1865A human PRP8 RNase H-like domain with bound Mg ion | 分子名称: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
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