2ZDT
 
 | | Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor | | 分子名称: | 4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1H)-yl)methyl]benzoic acid, GLYCEROL, Mitogen-activated protein kinase 10 | | 著者 | Sogabe, S, Asano, Y, Fukumoto, S, Habuka, N, Fujishima, A. | | 登録日 | 2007-11-27 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2)
Bioorg.Med.Chem., 16, 2008
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1J2A
 | | Structure of E. coli cyclophilin B K163T mutant | | 分子名称: | cyclophilin B | | 著者 | Konno, M, Sano, Y, Okudaira, K, Kawaguchi, Y, Yamagishi-Ohmori, Y, Fushinobu, S, Matsuzawa, H. | | 登録日 | 2002-12-26 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Escherichia coli cyclophilin B binds a highly distorted form of trans-prolyl peptide isomer
Eur.J.Biochem., 271, 2004
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1V9T
 | | Structure of E. coli cyclophilin B K163T mutant bound to succinyl-ALA-PRO-ALA-P-nitroanilide | | 分子名称: | (SIN)APA(NIT), cyclophilin B | | 著者 | Konno, M, Sano, Y, Okudaira, K, Kawaguchi, Y, Yamagishi-Ohmori, Y, Fushinobu, S, Matsuzawa, H. | | 登録日 | 2004-02-03 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Escherichia coli cyclophilin B binds a highly distorted form of trans-prolyl peptide isomer
Eur.J.Biochem., 271, 2004
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1VAI
 | | Structure of e. coli cyclophilin B K163T mutant bound to n-acetyl-ala-ala-pro-ala-7-amino-4-methylcoumarin | | 分子名称: | (ACE)AAPA(MCM), cyclophilin B | | 著者 | Konno, M, Sano, Y, Okudaira, K, Kawaguchi, Y, Yamagishi-Ohmori, Y, Fushinobu, S, Matsuzawa, H. | | 登録日 | 2004-02-17 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Escherichia coli cyclophilin B binds a highly distorted form of trans-prolyl peptide isomer
Eur.J.Biochem., 271, 2004
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3DXW
 | | The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam | | 分子名称: | Alpha-amino-epsilon-caprolactam racemase, PYRIDOXAL-5'-PHOSPHATE, azepan-2-one | | 著者 | Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. | | 登録日 | 2008-07-25 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | The novel structure of a pyridoxal 5'-phosphate-dependent fold-type I racemase, alpha-amino-epsilon-caprolactam racemase from Achromobacter obae
Biochemistry, 48, 2009
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3DXV
 | | The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae | | 分子名称: | Alpha-amino-epsilon-caprolactam racemase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. | | 登録日 | 2008-07-25 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | The novel structure of a pyridoxal 5'-phosphate-dependent fold-type I racemase, alpha-amino-epsilon-caprolactam racemase from Achromobacter obae
Biochemistry, 48, 2009
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3WE0
 | | L-Amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid oxidase/monooxygenase | | 著者 | Im, D.H, Matsui, D, Fukuta, Y, Fushinobu, S, Isobe, K, Asano, Y. | | 登録日 | 2013-06-26 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mutational and crystallographic analysis of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813: Interconversion between oxidase and monooxygenase activities
FEBS Open Bio, 4, 2014
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1D2T
 | | CRYSTAL STRUCTURE OF ACID PHOSPHATASE FROM ESCHERICHIA BLATTAE | | 分子名称: | ACID PHOSPHATASE, SULFATE ION | | 著者 | Ishikawa, K, Mihara, Y, Gondoh, K, Suzuki, E, Asano, Y. | | 登録日 | 1999-09-28 | | 公開日 | 2000-12-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray structures of a novel acid phosphatase from Escherichia blattae and its complex with the transition-state analog molybdate.
EMBO J., 19, 2000
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6JHC
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5Y1F
 | | Monomeric L-threonine 3-dehydrogenase from metagenome database (NAD+ bound form) | | 分子名称: | NAD dependent epimerase/dehydratase family, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Motoyama, T, Nakano, S, Yamamoto, Y, Tokiwa, H, Asano, Y, Ito, S. | | 登録日 | 2017-07-20 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Product Release Mechanism Associated with Structural Changes in Monomeric l-Threonine 3-Dehydrogenase.
Biochemistry, 56, 2017
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5Y1G
 | | Monomeric L-threonine 3-dehydrogenase from metagenome database (AKB and NADH bound form) | | 分子名称: | 2-AMINO-3-KETOBUTYRIC ACID, NAD dependent epimerase/dehydratase family, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Motoyama, T, Nakano, S, Yamamoto, Y, Tokiwa, H, Asano, Y, Ito, S. | | 登録日 | 2017-07-20 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Product Release Mechanism Associated with Structural Changes in Monomeric l-Threonine 3-Dehydrogenase.
Biochemistry, 56, 2017
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5Y1E
 | | monomeric L-threonine 3-dehydrogenase from metagenome database (L-Ser and NAD+ bound form) | | 分子名称: | NAD dependent epimerase/dehydratase family, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SERINE | | 著者 | Motoyama, T, Nakano, S, Yamamoto, Y, Tokiwa, H, Asano, Y, Ito, S. | | 登録日 | 2017-07-20 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Product Release Mechanism Associated with Structural Changes in Monomeric l-Threonine 3-Dehydrogenase.
Biochemistry, 56, 2017
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5Y1D
 | | Monomeric L-threonine 3-dehydrogenase from metagenome database (apo form) | | 分子名称: | NAD dependent epimerase/dehydratase family | | 著者 | Motoyama, T, Nakano, S, Yamamoto, Y, Tokiwa, H, Asano, Y, Ito, S. | | 登録日 | 2017-07-20 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Product Release Mechanism Associated with Structural Changes in Monomeric l-Threonine 3-Dehydrogenase.
Biochemistry, 56, 2017
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3WEU
 | | Crystal structure of the L-Lys epsilon-oxidase from Marinomonas mediterranea | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, L-lysine 6-oxidase, ... | | 著者 | Okazaki, S, Nakano, S, Matsui, D, Akaji, S, Inagaki, K, Asano, Y. | | 登録日 | 2013-07-12 | | 公開日 | 2013-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | X-Ray crystallographic evidence for the presence of the cysteine tryptophylquinone cofactor in L-lysine {varepsilon}-oxidase from Marinomonas mediterranea
J.Biochem., 154, 2013
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3WMX
 | | GalE-like L-Threonine dehydrogenase from Cupriavidus necator (holo form) | | 分子名称: | NAD dependent epimerase/dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, THREONINE | | 著者 | Nakano, S, Okazaki, S, Tokiwa, H, Asano, Y. | | 登録日 | 2013-11-29 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Binding of NAD+ and L-Threonine Induces Stepwise Structural and Flexibility Changes in Cupriavidus necator L-Threonine Dehydrogenase
J.Biol.Chem., 289, 2014
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7F30
 | | Crystal structure of OxdB E85A in complex with Z-2- (3-bromophenyl) propanal oxime | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Phenylacetaldoxime dehydratase, Z-2-(3-bromophenyl) propanal oxime | | 著者 | Muraki, N, Matsui, D, Asano, Y, Aono, S. | | 登録日 | 2021-06-15 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structural analysis of aldoxime dehydratase from Bacillus sp. OxB-1: Importance of surface residues in optimization for crystallization.
J.Inorg.Biochem., 230, 2022
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7F2Y
 | | Crystal structure of OxdB E85A mutant (form I) | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Phenylacetaldoxime dehydratase | | 著者 | Muraki, N, Matsui, D, Asano, Y, Aono, S. | | 登録日 | 2021-06-15 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structural analysis of aldoxime dehydratase from Bacillus sp. OxB-1: Importance of surface residues in optimization for crystallization.
J.Inorg.Biochem., 230, 2022
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7F2Z
 | | Crystal structure of OxdB E85A mutant (form II) | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Phenylacetaldoxime dehydratase | | 著者 | Muraki, N, Matsui, D, Asano, Y, Aono, S. | | 登録日 | 2021-06-15 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structural analysis of aldoxime dehydratase from Bacillus sp. OxB-1: Importance of surface residues in optimization for crystallization.
J.Inorg.Biochem., 230, 2022
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1KKO
 | | CRYSTAL STRUCTURE OF CITROBACTER AMALONATICUS METHYLASPARTATE AMMONIA LYASE | | 分子名称: | 3-METHYLASPARTATE AMMONIA-LYASE, SULFATE ION | | 著者 | Levy, C.W, Buckley, P.A, Sedelnikova, S, Kato, Y, Asano, Y, Rice, D.W, Baker, P.J. | | 登録日 | 2001-12-10 | | 公開日 | 2002-01-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase.
Structure, 10, 2002
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1IW8
 | | Crystal Structure of a mutant of acid phosphatase from Escherichia blattae (G74D/I153T) | | 分子名称: | SULFATE ION, acid phosphatase | | 著者 | Ishikawa, K, Mihara, Y, Shimba, N, Ohtsu, N, Kawasaki, H, Suzuki, E, Asano, Y. | | 登録日 | 2002-04-22 | | 公開日 | 2002-09-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Enhancement of nucleoside phosphorylation activity in an acid phosphatase
PROTEIN ENG., 15, 2002
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1KKR
 | | CRYSTAL STRUCTURE OF CITROBACTER AMALONATICUS METHYLASPARTATE AMMONIA LYASE CONTAINING (2S,3S)-3-METHYLASPARTIC ACID | | 分子名称: | (2S,3S)-3-methyl-aspartic acid, 3-METHYLASPARTATE AMMONIA-LYASE, MAGNESIUM ION | | 著者 | Levy, C.W, Buckley, P.A, Sedelnikova, S, Kato, K, Asano, Y, Rice, D.W, Baker, P.J. | | 登録日 | 2001-12-10 | | 公開日 | 2002-01-30 | | 最終更新日 | 2014-11-19 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase.
Structure, 10, 2002
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3WWP
 | | S-selective hydroxynitrile lyase from Baliospermum montanum (apo2) | | 分子名称: | (S)-hydroxynitrile lyase, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Nakano, S, Dadashipour, M, Asano, Y. | | 登録日 | 2014-06-23 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional analysis of hydroxynitrile lyase from Baliospermum montanum with crystal structure, molecular dynamics and enzyme kinetics
Biochim.Biophys.Acta, 1844, 2014
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5Z76
 | | Artificial L-threonine 3-dehydrogenase designed by full consensus design | | 分子名称: | Artificial L-threonine 3-dehydrogenase | | 著者 | Nakano, S, Motoyama, T, Miyashita, Y, Ishizuka, Y, Matsuo, N, Tokiwa, H, Shinoda, S, Asano, Y, Ito, S. | | 登録日 | 2018-01-27 | | 公開日 | 2018-08-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Benchmark Analysis of Native and Artificial NAD+-Dependent Enzymes Generated by a Sequence-Based Design Method with or without Phylogenetic Data.
Biochemistry, 57, 2018
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3X3H
 | | Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) 3KP (K176P, K199P, K224P) triple mutant | | 分子名称: | (S)-hydroxynitrile lyase | | 著者 | Cielo, C.B.C, Yamane, T, Asano, Y, Dadashipour, M, Suzuki, A, Mizushima, T, Komeda, H, Okazaki, S. | | 登録日 | 2015-01-21 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Crystallographic Studies of Manihot esculenta hydroxynitrile lyase Lysine-to-Proline mutants
TO BE PUBLISHED
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5Z75
 | | Artificial L-threonine 3-dehydrogenase designed by ancestral sequence reconstruction. | | 分子名称: | Artificial L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NONAETHYLENE GLYCOL, ... | | 著者 | Nakano, S, Motoyama, T, Miyashita, Y, Ishizuka, Y, Matsuo, N, Tokiwa, H, Shinoda, S, Asano, Y, Ito, S. | | 登録日 | 2018-01-27 | | 公開日 | 2018-08-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Benchmark Analysis of Native and Artificial NAD+-Dependent Enzymes Generated by a Sequence-Based Design Method with or without Phylogenetic Data.
Biochemistry, 57, 2018
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