5Z75
Artificial L-threonine 3-dehydrogenase designed by ancestral sequence reconstruction.
Summary for 5Z75
Entry DOI | 10.2210/pdb5z75/pdb |
Descriptor | Artificial L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | ancestral sequence reconstruction, l-threonine 3-dehydrogenase, oxidoreductase |
Biological source | synthetic construct |
Total number of polymer chains | 4 |
Total formula weight | 151937.91 |
Authors | Nakano, S.,Motoyama, T.,Miyashita, Y.,Ishizuka, Y.,Matsuo, N.,Tokiwa, H.,Shinoda, S.,Asano, Y.,Ito, S. (deposition date: 2018-01-27, release date: 2018-08-22, Last modification date: 2023-11-22) |
Primary citation | Nakano, S.,Motoyama, T.,Miyashita, Y.,Ishizuka, Y.,Matsuo, N.,Tokiwa, H.,Shinoda, S.,Asano, Y.,Ito, S. Benchmark Analysis of Native and Artificial NAD+-Dependent Enzymes Generated by a Sequence-Based Design Method with or without Phylogenetic Data. Biochemistry, 57:3722-3732, 2018 Cited by PubMed: 29787243DOI: 10.1021/acs.biochem.8b00339 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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