5L7O
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5X08
| Crystal structure of broadly neutralizing anti-HIV-1 antibody 4E10, mutant Npro, with peptide bound | 分子名称: | ACETATE ION, CHLORIDE ION, Envelope glycoprotein gp160, ... | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L, Tsumoto, K. | 登録日 | 2017-01-20 | 公開日 | 2017-04-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane J. Mol. Biol., 429, 2017
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7EKB
| Crystal structure of 4E10 modified with pyrene acetamide | 分子名称: | ACETATE ION, Fab region of the heavy chain of broadly neutralizing antibody anti-HIV-1 4E10, Fab region of the light chain of the broadly neutralizing anti-HIV-1 antibody 4E10, ... | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L. | 登録日 | 2021-04-05 | 公開日 | 2021-08-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile. Iscience, 24, 2021
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7EKK
| Anti-HIV-1 broadly neutralizing antibody delta-loop 4E10 modified with pyrene acetamide | 分子名称: | AMMONIUM ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L. | 登録日 | 2021-04-05 | 公開日 | 2021-08-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile. Iscience, 24, 2021
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