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4Z7M
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BU of 4z7m by Molmil
Novel Inhibitors of Bacterial Methionine Aminopeptidase with Broad-Spectrum Biochemical Activity
分子名称: MANGANESE (II) ION, Methionine aminopeptidase, N~2~-[(3,5-difluorophenyl)acetyl]-N-[(3S,7R)-1-methyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-L-alaninamide
著者Rose, J.A, Lahiri, S.D, McKinney, D.C, Albert, R, Morningstar, M, Shapiro, A.B, Fisher, S.F, Fleming, P.R.
登録日2015-04-07
公開日2016-04-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Novel Inhibitors of Bacterial Methionine Aminopeptidase with Broad-Spectrum Biochemical Activity
To be Published
2BAY
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BU of 2bay by Molmil
Crystal structure of the Prp19 U-box dimer
分子名称: Pre-mRNA splicing factor PRP19
著者Vander Kooi, C.W, Ohi, M.D, Rosenberg, J.A, Oldham, M.L, Newcomer, M.E, Gould, K.L, Chazin, W.J.
登録日2005-10-15
公開日2006-01-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Prp19 U-box Crystal Structure Suggests a Common Dimeric Architecture for a Class of Oligomeric E3 Ubiquitin Ligases.
Biochemistry, 45, 2006
4EMV
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BU of 4emv by Molmil
Crystal structure of a topoisomerase ATP inhibitor
分子名称: 5-{2-(ethylcarbamoyl)-4-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl}pyridine-3-carboxylic acid, DNA topoisomerase IV, B subunit
著者Boriack-Sjodin, P.A, Manchester, J, Hull, K.
登録日2012-04-12
公開日2012-08-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV.
Bioorg.Med.Chem.Lett., 22, 2012
4EM7
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BU of 4em7 by Molmil
Crystal structure of a topoisomerase ATP inhibitor
分子名称: 3-[3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]propanoic acid, DNA topoisomerase IV, B subunit
著者Boriack-Sjodin, P.A, Manchester, J.
登録日2012-04-11
公開日2012-08-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV.
Bioorg.Med.Chem.Lett., 22, 2012
1N87
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BU of 1n87 by Molmil
Solution structure of the U-box of Prp19
分子名称: Pre-mRNA splicing factor PRP19
著者Chazin, W.J, Ohi, M.D, Vander Kooi, C.W.
登録日2002-11-19
公開日2003-04-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural insights into the U-box, a domain associated with multi-ubiquitination
Nat.Struct.Biol., 10, 2003

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件を2024-10-30に公開中

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