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7F3U
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BU of 7f3u by Molmil
Cryo-EM structure of human TMEM120A in the CoASH-free state
分子名称: Transmembrane protein 120A
著者Rong, Y, Gao, Y.W, Song, D.F, Zhao, Y, Liu, Z.F.
登録日2021-06-17
公開日2021-06-30
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells.
Elife, 10, 2021
7F3T
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BU of 7f3t by Molmil
Cryo-EM structure of human TMEM120A in the CoASH-bound state
分子名称: COENZYME A, Transmembrane protein 120A
著者Song, D.F, Rong, Y, Liu, Z.F.
登録日2021-06-17
公開日2021-06-30
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells.
Elife, 10, 2021
4WY4
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BU of 4wy4 by Molmil
Crystal structure of autophagic SNARE complex
分子名称: Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8
著者Zhao, M, Brunger, A.T.
登録日2014-11-15
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Nature, 520, 2015
5J57
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BU of 5j57 by Molmil
V5E1-RTA complex
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ...
著者Rudolph, M.J.
登録日2016-04-01
公開日2016-12-07
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.
J. Biol. Chem., 292, 2017
5J56
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BU of 5j56 by Molmil
RTA-V1C7
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ...
著者Rudolph, M.J.
登録日2016-04-01
公開日2016-12-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.
J. Biol. Chem., 292, 2017
6CWK
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BU of 6cwk by Molmil
Anti-RTA VHH antibody
分子名称: 1,2-ETHANEDIOL, Anti-Ricin antibody, CHLORIDE ION, ...
著者Rudolph, M.J, Mantis, N.
登録日2018-03-30
公開日2019-01-16
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.256 Å)
主引用文献Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
6CWG
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BU of 6cwg by Molmil
Ricin catalytic subunit bound go A9 VHH antibody
分子名称: CHLORIDE ION, Ricin, VHH antibody
著者Rudolph, M.J, Mantis, N.
登録日2018-03-30
公開日2019-01-16
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
5U4M
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BU of 5u4m by Molmil
RTA-V1C7-G29R-no_salt
分子名称: CHLORIDE ION, Ricin, V1C7 VHH antibody
著者Rudolph, M.J, Mantis, N.
登録日2016-12-05
公開日2017-12-13
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies.
Proteins, 85, 2017
5U4L
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BU of 5u4l by Molmil
RTA-V1C7_G29R-high-salt
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ...
著者Rudolph, M.J, Mantis, N.
登録日2016-12-05
公開日2017-12-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies.
Proteins, 85, 2017
5E1H
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BU of 5e1h by Molmil
Ricin toxin in complex with neutralizing single chain monoclonal antibodies (VHHs)
分子名称: CHLORIDE ION, F8(JOB10) VHH antibody, Ricin
著者Rudolph, M.J, Vance, D, Shoemaker, C, Mantis, N.
登録日2015-09-29
公開日2016-08-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.032 Å)
主引用文献Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins, 84, 2016
4Z9K
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BU of 4z9k by Molmil
Ricin A chain bound to camelid nanobody (VHH2)(F5)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ...
著者Rudolph, M.J.
登録日2015-04-10
公開日2016-07-20
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins, 84, 2016
5BOZ
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BU of 5boz by Molmil
Ricin A chain bound to camelid nanobody (VHH9)(E1)
分子名称: CHLORIDE ION, Ricin, SULFATE ION, ...
著者Rudolph, M.J, Mantis, N.
登録日2015-05-27
公開日2016-12-07
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.
J. Biol. Chem., 292, 2017
4RE1
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BU of 4re1 by Molmil
Crystal structure of human TEAD1 and disulfide-engineered YAP
分子名称: CHLORIDE ION, Transcriptional enhancer factor TEF-1, Yorkie homolog
著者Xu, Z, Zhou, Z.
登録日2014-09-21
公開日2014-11-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides.
Faseb J., 29, 2015
7DV4
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BU of 7dv4 by Molmil
Crystal structure of anti-CTLA-4 VH domain in complex with human CTLA-4
分子名称: 1,2-ETHANEDIOL, 4003-1(VH), Cytotoxic T-lymphocyte protein 4
著者Li, H, Gan, X, He, Y.
登録日2021-01-12
公開日2022-01-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献An anti-CTLA-4 heavy chain-only antibody with enhanced T reg depletion shows excellent preclinical efficacy and safety profile.
Proc.Natl.Acad.Sci.USA, 119, 2022

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件を2024-06-12に公開中

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