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1S0U
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BU of 1s0u by Molmil
eIF2gamma apo
分子名称: Translation initiation factor 2 gamma subunit, ZINC ION
著者Roll-Mecak, A, Alone, P, Cao, C, Dever, T.E, Burley, S.K.
登録日2004-01-04
公開日2004-01-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray Structure of Translation Initiation Factor eIF2gamma: IMPLICATIONS FOR tRNA AND eIF2alpha BINDING.
J.Biol.Chem., 279, 2004
3B9P
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BU of 3b9p by Molmil
Spastin
分子名称: CG5977-PA, isoform A, CHLORIDE ION
著者Roll-Mecak, A, Vale, R.D.
登録日2007-11-06
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin.
Nature, 451, 2008
1G7R
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BU of 1g7r by Molmil
X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B
分子名称: TRANSLATION INITIATION FACTOR IF2/EIF5B
著者Roll-Mecak, A, Cao, C, Dever, T.E, Burley, S.K.
登録日2000-11-14
公開日2000-12-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding.
Cell(Cambridge,Mass.), 103, 2000
1G7S
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BU of 1g7s by Molmil
X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B COMPLEXED WITH GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, TRANSLATION INITIATION FACTOR IF2/EIF5B
著者Roll-Mecak, A, Cao, C, Dever, T.E, Burley, S.K.
登録日2000-11-14
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding.
Cell(Cambridge,Mass.), 103, 2000
1G7T
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BU of 1g7t by Molmil
X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B COMPLEXED WITH GDPNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, TRANSLATION INITIATION FACTOR IF2/EIF5B
著者Roll-Mecak, A, Cao, C, Dever, T.E, Burley, S.K.
登録日2000-11-14
公開日2000-12-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding.
Cell(Cambridge,Mass.), 103, 2000
3TIN
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BU of 3tin by Molmil
Tubulin tyrosine ligase
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ttl protein
著者Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G.
登録日2011-08-20
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
3TII
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BU of 3tii by Molmil
Tubulin tyrosine ligase
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ttl protein
著者Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G.
登録日2011-08-20
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
3TIG
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BU of 3tig by Molmil
Tubulin tyrosine ligase
分子名称: MAGNESIUM ION, Ttl protein
著者Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G.
登録日2011-08-20
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
4H6U
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BU of 4h6u by Molmil
Tubulin acetyltransferase mutant
分子名称: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, PHOSPHATE ION, ...
著者Roll-Mecak, A, Kizub, V, Szyk, A.
登録日2012-09-19
公開日2012-11-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4482 Å)
主引用文献Crystal structures of tubulin acetyltransferase reveal a conserved catalytic core and the plasticity of the essential N terminus.
J.Biol.Chem., 287, 2012
4YLS
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BU of 4yls by Molmil
Tubulin Glutamylase
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tubulin polyglutamylase TTLL7
著者Garnham, C.P, Vemu, A, Wilson-Kubalek, E.M, Yu, I, Szyk, A, Lander, G.C, Milligan, R.A, Roll-Mecak, A.
登録日2015-03-05
公開日2015-06-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
6UGF
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BU of 6ugf by Molmil
Katanin hexamer in the ring conformation with resolved protomer one in complex with substrate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Meiotic spindle formation protein mei-1, ...
著者Zehr, E.A, Roll-Mecak, A.
登録日2019-09-26
公開日2019-10-09
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Katanin Grips the beta-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules.
Dev.Cell, 52, 2020
8T42
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BU of 8t42 by Molmil
Model of TTLL6 MTBH1-2 bound to microtubule
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Mahalingan, K.K, Grotjahn, D, Li, Y, Lander, G.C, Zehr, E.A, Roll-Mecak, A.
登録日2023-06-08
公開日2024-05-08
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for alpha-tubulin-specific and modification state-dependent glutamylation.
Nat.Chem.Biol., 20, 2024
9BP6
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BU of 9bp6 by Molmil
Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Zehr, E.A, Roll-Mecak, A.
登録日2024-05-07
公開日2024-06-12
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of human alpha 1B/ beta I+ beta IVb microtubules shed light on isoform specific assembly
Biorxiv, 2023
5JCO
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BU of 5jco by Molmil
Structure and dynamics of single-isoform recombinant neuronal human tubulin
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Vemu, A, Atherton, J, Spector, J.O, Szyk, A, Moores, C.A, Roll-Mecak, A.
登録日2016-04-15
公開日2016-05-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin.
J.Biol.Chem., 291, 2016
4YLR
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BU of 4ylr by Molmil
Tubulin Glutamylase
分子名称: ADENOSINE-5'-DIPHOSPHATE, Tubulin polyglutamylase TTLL7
著者Garnham, C.P, Vemu, A, Wilson-Kubalek, E.M, Yu, I, Szyk, A, Lander, G.C, Milligan, R.A, Roll-Mecak, A.
登録日2015-03-05
公開日2015-06-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
5N5N
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BU of 5n5n by Molmil
Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Vemu, A, Atherton, J, Spector, J.O, Moores, C.A, Roll-Mecak, A.
登録日2017-02-14
公開日2017-11-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Tubulin isoform composition tunes microtubule dynamics.
Mol. Biol. Cell, 28, 2017
4PK2
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BU of 4pk2 by Molmil
tubulin acetyltransferase complex with bisubstrate analog
分子名称: ACETYL-SER-(N-PROPANOYL-LYS)-ASP--THR-NH2 PEPTIDE, Alpha-tubulin N-acetyltransferase 1, COENZYME A
著者Szyk, A, Roll-Mecak, A.
登録日2014-05-13
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.
Cell, 157, 2014
4H6Z
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BU of 4h6z by Molmil
Tubulin acetyltransferase
分子名称: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, PHOSPHATE ION
著者Kizub, L, Szyk, A, Piszczek, G, Roll-Mecak, A.
登録日2012-09-19
公開日2012-11-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Crystal structures of tubulin acetyltransferase reveal a conserved catalytic core and the plasticity of the essential N terminus.
J.Biol.Chem., 287, 2012
4PK3
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BU of 4pk3 by Molmil
tubulin acetyltransferase complex with bisubstrate analog
分子名称: ACETYL-SER-ASP-(N-ACETYL-LYS)-THR-NH2 PEPTIDE, Alpha-tubulin N-acetyltransferase 1, COENZYME A
著者Szyk, A, Roll-Mecak, A.
登録日2014-05-13
公開日2014-08-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.347 Å)
主引用文献Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.
Cell, 157, 2014
6UGD
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BU of 6ugd by Molmil
Katanin hexamer in the spiral conformation in complex with substrate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Meiotic spindle formation protein mei-1, ...
著者Zehr, E.A, Roll-Mecak, A.
登録日2019-09-26
公開日2019-10-09
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Katanin Grips the beta-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules.
Dev.Cell, 52, 2020
6UGE
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BU of 6uge by Molmil
Katanin hexamer in the ring conformation in complex with substrate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Meiotic spindle formation protein mei-1, ...
著者Zehr, E.A, Roll-Mecak, A.
登録日2019-09-26
公開日2019-10-09
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Katanin Grips the beta-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules.
Dev.Cell, 52, 2020
1ZY4
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BU of 1zy4 by Molmil
Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant in Apo Form.
分子名称: GLYCEROL, Serine/threonine-protein kinase GCN2
著者Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K.
登録日2005-06-09
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
1ZYC
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BU of 1zyc by Molmil
Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type in Apo Form.
分子名称: Serine/threonine-protein kinase GCN2
著者Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K.
登録日2005-06-09
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
5WC1
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BU of 5wc1 by Molmil
katanin AAA ATPase domain
分子名称: Meiotic spindle formation protein mei-1, SULFATE ION
著者Szyk, A, Roll-Mecak, A.
登録日2017-06-29
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Katanin spiral and ring structures shed light on power stroke for microtubule severing.
Nat. Struct. Mol. Biol., 24, 2017
5WCB
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BU of 5wcb by Molmil
Katanin hexamer in the ring conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Meiotic spindle formation protein mei-1
著者Zehr, E.A, Szyk, A, Piszczek, G, Szczesna, E, Zuo, X, Roll-Mecak, A.
登録日2017-06-29
公開日2017-08-09
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Katanin spiral and ring structures shed light on power stroke for microtubule severing.
Nat. Struct. Mol. Biol., 24, 2017

 

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