1S0U
 
 | | eIF2gamma apo | | 分子名称: | Translation initiation factor 2 gamma subunit, ZINC ION | | 著者 | Roll-Mecak, A, Alone, P, Cao, C, Dever, T.E, Burley, S.K. | | 登録日 | 2004-01-04 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray Structure of Translation Initiation Factor eIF2gamma: IMPLICATIONS FOR tRNA AND eIF2alpha BINDING.
J.Biol.Chem., 279, 2004
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3B9P
 | | Spastin | | 分子名称: | CG5977-PA, isoform A, CHLORIDE ION | | 著者 | Roll-Mecak, A, Vale, R.D. | | 登録日 | 2007-11-06 | | 公開日 | 2008-01-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin.
Nature, 451, 2008
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1G7S
 | | X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B COMPLEXED WITH GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, TRANSLATION INITIATION FACTOR IF2/EIF5B | | 著者 | Roll-Mecak, A, Cao, C, Dever, T.E, Burley, S.K. | | 登録日 | 2000-11-14 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding.
Cell(Cambridge,Mass.), 103, 2000
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1G7R
 | | X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B | | 分子名称: | TRANSLATION INITIATION FACTOR IF2/EIF5B | | 著者 | Roll-Mecak, A, Cao, C, Dever, T.E, Burley, S.K. | | 登録日 | 2000-11-14 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding.
Cell(Cambridge,Mass.), 103, 2000
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1G7T
 | | X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B COMPLEXED WITH GDPNP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, TRANSLATION INITIATION FACTOR IF2/EIF5B | | 著者 | Roll-Mecak, A, Cao, C, Dever, T.E, Burley, S.K. | | 登録日 | 2000-11-14 | | 公開日 | 2000-12-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding.
Cell(Cambridge,Mass.), 103, 2000
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4H6U
 | | Tubulin acetyltransferase mutant | | 分子名称: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, PHOSPHATE ION, ... | | 著者 | Roll-Mecak, A, Kizub, V, Szyk, A. | | 登録日 | 2012-09-19 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4482 Å) | | 主引用文献 | Crystal structures of tubulin acetyltransferase reveal a conserved catalytic core and the plasticity of the essential N terminus.
J.Biol.Chem., 287, 2012
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3TIN
 | | Tubulin tyrosine ligase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ttl protein | | 著者 | Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G. | | 登録日 | 2011-08-20 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
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3TII
 | | Tubulin tyrosine ligase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ttl protein | | 著者 | Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G. | | 登録日 | 2011-08-20 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
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3TIG
 | | Tubulin tyrosine ligase | | 分子名称: | MAGNESIUM ION, Ttl protein | | 著者 | Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G. | | 登録日 | 2011-08-20 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
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9BP6
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5JCO
 | | Structure and dynamics of single-isoform recombinant neuronal human tubulin | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Vemu, A, Atherton, J, Spector, J.O, Szyk, A, Moores, C.A, Roll-Mecak, A. | | 登録日 | 2016-04-15 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin.
J.Biol.Chem., 291, 2016
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5N5N
 | | Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Vemu, A, Atherton, J, Spector, J.O, Moores, C.A, Roll-Mecak, A. | | 登録日 | 2017-02-14 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Tubulin isoform composition tunes microtubule dynamics.
Mol. Biol. Cell, 28, 2017
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8T42
 | | Model of TTLL6 MTBH1-2 bound to microtubule | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Mahalingan, K.K, Grotjahn, D, Li, Y, Lander, G.C, Zehr, E.A, Roll-Mecak, A. | | 登録日 | 2023-06-08 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for alpha-tubulin-specific and modification state-dependent glutamylation.
Nat.Chem.Biol., 20, 2024
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8U3Z
 | | Model of TTLL6 bound to microtubule from composite map | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Mahalingan, K.K, Grotjahn, D, Li, Y, Lander, G.C, Zehr, E.A, Roll-Mecak, A. | | 登録日 | 2023-09-08 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for alpha-tubulin-specific and modification state-dependent glutamylation.
Nat.Chem.Biol., 20, 2024
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1ZYD
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type Complexed with ATP. | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase GCN2 | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-09 | | 公開日 | 2005-06-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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4YLS
 | | Tubulin Glutamylase | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tubulin polyglutamylase TTLL7 | | 著者 | Garnham, C.P, Vemu, A, Wilson-Kubalek, E.M, Yu, I, Szyk, A, Lander, G.C, Milligan, R.A, Roll-Mecak, A. | | 登録日 | 2015-03-05 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
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4YLR
 | | Tubulin Glutamylase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Tubulin polyglutamylase TTLL7 | | 著者 | Garnham, C.P, Vemu, A, Wilson-Kubalek, E.M, Yu, I, Szyk, A, Lander, G.C, Milligan, R.A, Roll-Mecak, A. | | 登録日 | 2015-03-05 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
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1ZY4
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant in Apo Form. | | 分子名称: | GLYCEROL, Serine/threonine-protein kinase GCN2 | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-09 | | 公開日 | 2005-06-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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1ZXE
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: D835N Inactivating Mutant in Apo Form | | 分子名称: | GLYCEROL, Serine/threonine-protein kinase | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-07 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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1ZYC
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type in Apo Form. | | 分子名称: | Serine/threonine-protein kinase GCN2 | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-09 | | 公開日 | 2005-06-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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1ZY5
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant Complexed with AMPPNP. | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase GCN2 | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-09 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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4PK2
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4H6Z
 | | Tubulin acetyltransferase | | 分子名称: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, PHOSPHATE ION | | 著者 | Kizub, L, Szyk, A, Piszczek, G, Roll-Mecak, A. | | 登録日 | 2012-09-19 | | 公開日 | 2012-11-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Crystal structures of tubulin acetyltransferase reveal a conserved catalytic core and the plasticity of the essential N terminus.
J.Biol.Chem., 287, 2012
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4PK3
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8V3O
 | | CCP5 in complex with Glu-P-peptide 1 transition state analog | | 分子名称: | Cytosolic carboxypeptidase-like protein 5, D-MALATE, POTASSIUM ION, ... | | 著者 | Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | | 登録日 | 2023-11-28 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Nature, 631, 2024
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